| Literature DB >> 1486392 |
D J Ralph1, M D Brooks, G F Bottazzo, J P Pryor.
Abstract
This is a preliminary study of the treatment of 36 patients with Peyronie's disease who received tamoxifen 20 mg twice daily for 3 months. An improvement occurred in 16 of 20 patients with penile pain, in 11 of 31 patients with an erectile deformity and 12 of 35 patients had a plaque shrinkage of at least 1 cm. Some improvement occurred in 6 of the 8 patients with a histologically confirmed inflammatory infiltrate of the plaque but not in any of the 4 patients without an infiltrate. The inflammatory infiltrate was found in patients in whom the duration of the disease was less than 4 months.Entities:
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Year: 1992 PMID： 1486392 DOI： 10.1111/j.1464-410x.1992.tb15836.x
Source DB: PubMed Journal: Br J Urol ISSN： 0007-1331