Literature DB >> 23996985

Proximal humerus and humeral shaft nonunions.

Edwin R Cadet1, Bob Yin, Brian Schulz, Christopher S Ahmad, Melvin P Rosenwasser.   

Abstract

The rate of nonunion is estimated to be 1.1% to 10% following closed treatment of proximal humerus fracture and 5.5% following closed treatment of humeral shaft fracture. Surgical management should be considered for fractures that demonstrate no evidence of progressive healing on consecutive radiographs taken at least 6 to 8 weeks apart during the course of closed treatment. In the case of proximal humerus nonunion, recent series have demonstrated union in >90% of patients treated with reconstruction using locking plates and autogenous bone graft. Shoulder arthroplasty is reserved as a salvage option in cases in which the humeral head is not viable or the proximal fragment will not support osteosynthesis. For humeral shaft nonunions, open reduction and internal fixation with compression plating and bone graft remains the standard of care, with a >90% rate of union and good functional outcomes. Recent studies support the use of locked compression plates, dual plating, and cortical allograft struts in patients with osteopenic bone.

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Mesh:

Year:  2013        PMID: 23996985     DOI: 10.5435/JAAOS-21-09-538

Source DB:  PubMed          Journal:  J Am Acad Orthop Surg        ISSN: 1067-151X            Impact factor:   3.020


  15 in total

1.  Humeral shaft hypertrophic non-union mimicking malignant lesion.

Authors:  Hosam E Matar; Karthikeyan P Iyengar; Eugene M Toh
Journal:  BMJ Case Rep       Date:  2013-12-11

2.  Exogenous hedgehog antagonist delays but does not prevent fracture healing in young mice.

Authors:  Xiaochen Liu; Jennifer A McKenzie; Clayton W Maschhoff; Michael J Gardner; Matthew J Silva
Journal:  Bone       Date:  2017-07-19       Impact factor: 4.398

3.  Repair of proximal humerus fracture nonunions using a standardized treatment algorithm: a case series.

Authors:  Kurtis D Carlock; Sanjit R Konda; Isabella R Bianco; Joseph D Zuckerman; Kenneth A Egol
Journal:  Eur J Orthop Surg Traumatol       Date:  2021-01-08

Review 4.  Management of proximal humerus fractures in adults.

Authors:  Leonidas Vachtsevanos; Lydia Hayden; Aravind S Desai; Asterios Dramis
Journal:  World J Orthop       Date:  2014-11-18

Review 5.  [Posttraumatic nonunions and malunions of the proximal humerus. Possibilities and limitations of corrective osteotomy].

Authors:  R Meller; N Hawi; U Schmiddem; P J Millett; M Petri; C Krettek
Journal:  Unfallchirurg       Date:  2015-07       Impact factor: 1.000

6.  Early outcomes of magnetic intramedullary compression nailing for humeral fractures.

Authors:  Khang H Dang; Katherine Jensen; Anil K Dutta
Journal:  Eur J Orthop Surg Traumatol       Date:  2020-07-07

7.  Ablation of Proliferating Osteoblast Lineage Cells After Fracture Leads to Atrophic Nonunion in a Mouse Model.

Authors:  Katherine R Hixon; Jennifer A McKenzie; David A W Sykes; Susumu Yoneda; Austin Hensley; Evan G Buettmann; Hongjun Zheng; Dimitrios Skouteris; Audrey McAlinden; Anna N Miller; Matthew J Silva
Journal:  J Bone Miner Res       Date:  2021-09-07       Impact factor: 6.741

8.  Trehalose enhances bone fracture healing in a rat sleep deprivation model.

Authors:  Xingquan Xu; Rongliang Wang; Ziying Sun; Rui Wu; Wenjin Yan; Qing Jiang; Dongquan Shi
Journal:  Ann Transl Med       Date:  2019-07

9.  Conservative Treatment for Bilateral Displaced Proximal Humerus Head Fracture.

Authors:  Ruy E Rodriguez-Corlay; Ricardo Velutini-Becker; Luis D Aguilar-Alcalá
Journal:  Cureus       Date:  2016-06-27

10.  Antagonizing midkine accelerates fracture healing in mice by enhanced bone formation in the fracture callus.

Authors:  Melanie Haffner-Luntzer; Aline Heilmann; Anna Elise Rapp; Robin Roessler; Thorsten Schinke; Michael Amling; Anita Ignatius; Astrid Liedert
Journal:  Br J Pharmacol       Date:  2016-05-29       Impact factor: 8.739

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