Literature DB >> 2398545

Identification of cis-acting repressive sequences within the negative regulatory element of human immunodeficiency virus type 1.

Y C Lu1, N Touzjian, M Stenzel, T Dorfman, J G Sodroski, W A Haseltine.   

Abstract

The negative regulatory element of human immunodeficiency virus type 1 is a 260-nucleotide-long sequence that decreases the rate of RNA transcription initiation specified by the long terminal repeat. This region has the potential to bind several cellular transcription factors. Here it is shown that sequences which recognize the NFAT-1 and USF cellular transcription factors contribute to this negative regulatory effect. The sequences within the negative regulatory element which resemble the AP-1 site and the URS do not negatively regulate human immunodeficiency virus long terminal repeat transcription initiation.

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Year:  1990        PMID： 2398545      PMCID： PMC248024     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  13 in total

1.  The trans-activator gene of the human T cell lymphotropic virus type III is required for replication.

Authors:  A I Dayton; J G Sodroski; C A Rosen; W C Goh; W A Haseltine
Journal:  Cell       Date:  1986-03-28       Impact factor: 41.582

2.  Activation of the HIV-1 LTR by T cell mitogens and the trans-activator protein of HTLV-I.

Authors:  M Siekevitz; S F Josephs; M Dukovich; N Peffer; F Wong-Staal; W C Greene
Journal:  Science       Date:  1987-12-11       Impact factor: 47.728

3.  The location of cis-acting regulatory sequences in the human T cell lymphotropic virus type III (HTLV-III/LAV) long terminal repeat.

Authors:  C A Rosen; J G Sodroski; W A Haseltine
Journal:  Cell       Date:  1985-07       Impact factor: 41.582

4.  Ubiquitous upstream repression sequences control activation of the inducible arginase gene in yeast.

Authors:  R A Sumrada; T G Cooper
Journal:  Proc Natl Acad Sci U S A       Date:  1987-06       Impact factor: 11.205

5.  The same 50-kDa cellular protein binds to the negative regulatory elements of the interleukin 2 receptor alpha-chain gene and the human immunodeficiency virus type 1 long terminal repeat.

Authors:  M R Smith; W C Greene
Journal:  Proc Natl Acad Sci U S A       Date:  1989-11       Impact factor: 11.205

6.  The Fos complex and Fos-related antigens recognize sequence elements that contain AP-1 binding sites.

Authors:  B R Franza; F J Rauscher; S F Josephs; T Curran
Journal:  Science       Date:  1988-03-04       Impact factor: 47.728

7.  Rapid and efficient site-specific mutagenesis without phenotypic selection.

Authors:  T A Kunkel
Journal:  Proc Natl Acad Sci U S A       Date:  1985-01       Impact factor: 11.205

8.  An RNA polymerase II transcription factor binds to an upstream element in the adenovirus major late promoter.

Authors:  R W Carthew; L A Chodosh; P A Sharp
Journal:  Cell       Date:  1985-12       Impact factor: 41.582

9.  An inducible transcription factor activates expression of human immunodeficiency virus in T cells.

Authors:  G Nabel; D Baltimore
Journal:  Nature       Date:  1987 Apr 16-22       Impact factor: 49.962

10.  Interactions of cellular proteins involved in the transcriptional regulation of the human immunodeficiency virus.

Authors:  J A Garcia; F K Wu; R Mitsuyasu; R B Gaynor
Journal:  EMBO J       Date:  1987-12-01       Impact factor: 11.598
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  52 in total

1.  Modulation of HIV transcription by CD8(+) cells is mediated via multiple elements of the long terminal repeat.

Authors:  D M Maslove; L W Ni; N C Hawley-Foss; A D Badley; K F Copeland
Journal:  Clin Exp Immunol       Date:  2001-07       Impact factor: 4.330

2.  The Usf-1 transcription factor is a novel target for the stress-responsive p38 kinase and mediates UV-induced Tyrosinase expression.

Authors:  M D Galibert; S Carreira; C R Goding
Journal:  EMBO J       Date:  2001-09-03       Impact factor: 11.598

3.  Characterization of a novel T lymphocyte protein which binds to a site related to steroid/thyroid hormone receptor response elements in the negative regulatory sequence of the human immunodeficiency virus long terminal repeat.

Authors:  K Orchard; G Lang; M Collins; D Latchman
Journal:  Nucleic Acids Res       Date:  1992-10-25       Impact factor: 16.971

4.  Activation of the human immunodeficiency virus type 1 enhancer is not dependent on NFAT-1.

Authors:  D M Markovitz; M C Hannibal; M J Smith; R Cossman; G J Nabel
Journal:  J Virol       Date:  1992-06       Impact factor: 5.103

5.  Interactions of HTF4 with E-box motifs in the long terminal repeat of human immunodeficiency virus type 1.

Authors:  Y Zhang; K Doyle; M Bina
Journal:  J Virol       Date:  1992-09       Impact factor: 5.103

6.  Nuclear factors that bind two regions important to transcriptional activity of the simian immunodeficiency virus long terminal repeat.

Authors:  S Winandy; B Renjifo; Y Li; N Hopkins
Journal:  J Virol       Date:  1992-09       Impact factor: 5.103

7.  Probing protein-DNA interactions at the long terminal repeat of human immunodeficiency virus type 1 by in vivo footprinting.

Authors:  F Demarchi; P D'Agaro; A Falaschi; M Giacca
Journal:  J Virol       Date:  1992-04       Impact factor: 5.103

8.  Linker-scanning mutational analysis of the transcriptional activity of the human immunodeficiency virus type 1 long terminal repeat.

Authors:  S L Zeichner; J Y Kim; J C Alwine
Journal:  J Virol       Date:  1991-05       Impact factor: 5.103

9.  A nonproducer, interfering human immunodeficiency virus (HIV) type 1 provirus can be transduced through a murine leukemia virus-based retroviral vector: recovery of an anti-HIV mouse/human pseudotype retrovirus.

Authors:  M Federico; F Nappi; G Ferrari; C Chelucci; F Mavilio; P Verani
Journal:  J Virol       Date:  1995-11       Impact factor: 5.103

10.  NF-kappaB-repressing factor inhibits elongation of human immunodeficiency virus type 1 transcription by DRB sensitivity-inducing factor.

Authors:  Ursula Dreikhausen; Kirsten Hiebenthal-Millow; Myriam Bartels; Klaus Resch; Mahtab Nourbakhsh
Journal:  Mol Cell Biol       Date:  2005-09       Impact factor: 4.272
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