Literature DB >> 1437560

Characterization of a novel T lymphocyte protein which binds to a site related to steroid/thyroid hormone receptor response elements in the negative regulatory sequence of the human immunodeficiency virus long terminal repeat.

K Orchard1, G Lang, M Collins, D Latchman.   

Abstract

We have previously identified a T lymphocyte protein which binds to a site within the LTR of the human immunodeficiency virus type 1 (HIV-1) and exerts an inhibitory effect on virus gene expression. The palindromic site (site B) recognized by this protein is related to the palindromic binding sites of members of the steroid/thyroid hormone receptor family. Here we characterize the T cell protein binding to this site as a 100 kD protein which is most abundant in T cells and which binds to site B as a 200 kD complex. This protein is distinct from other members of the steroid/thyroid hormone receptor family including the COUP protein which has a closely related DNA binding specificity.

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Year:  1992        PMID: 1437560      PMCID: PMC334352          DOI: 10.1093/nar/20.20.5429

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN: 0305-1048            Impact factor:   16.971


  24 in total

1.  Linker-scanning mutational analysis of the transcriptional activity of the human immunodeficiency virus type 1 long terminal repeat.

Authors:  S L Zeichner; J Y Kim; J C Alwine
Journal:  J Virol       Date:  1991-05       Impact factor: 5.103

2.  Chicken ovalbumin upstream promoter transcription factor binds to a negative regulatory region in the human immunodeficiency virus type 1 long terminal repeat.

Authors:  A J Cooney; S Y Tsai; B W O'Malley; M J Tsai
Journal:  J Virol       Date:  1991-06       Impact factor: 5.103

3.  The COUP-TFs compose a family of functionally related transcription factors.

Authors:  L H Wang; N H Ing; S Y Tsai; B W O'Malley; M J Tsai
Journal:  Gene Expr       Date:  1991

4.  Interactions between a DNA-binding transcription factor (COUP) and a non-DNA binding factor (S300-II).

Authors:  S Y Tsai; I Sagami; H Wang; M J Tsai; B W O'Malley
Journal:  Cell       Date:  1987-08-28       Impact factor: 41.582

5.  Identification of two novel members of erbA superfamily by molecular cloning: the gene products of the two are highly related to each other.

Authors:  N Miyajima; Y Kadowaki; S Fukushige; S Shimizu; K Semba; Y Yamanashi; K Matsubara; K Toyoshima; T Yamamoto
Journal:  Nucleic Acids Res       Date:  1988-12-09       Impact factor: 16.971

6.  Molecular weights of protein multimers from polyacrylamide gel electrophoresis.

Authors:  J K Bryan
Journal:  Anal Biochem       Date:  1977-04       Impact factor: 3.365

7.  A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity.

Authors:  A P Feinberg; B Vogelstein
Journal:  Anal Biochem       Date:  1983-07-01       Impact factor: 3.365

8.  An inducible transcription factor activates expression of human immunodeficiency virus in T cells.

Authors:  G Nabel; D Baltimore
Journal:  Nature       Date:  1987 Apr 16-22       Impact factor: 49.962

9.  Activation of DNA-binding activity in an apparently cytoplasmic precursor of the NF-kappa B transcription factor.

Authors:  P A Baeuerle; D Baltimore
Journal:  Cell       Date:  1988-04-22       Impact factor: 41.582

10.  Primary structure of the human, membrane-associated Ca2+-binding protein p68 a novel member of a protein family.

Authors:  M R Crompton; R J Owens; N F Totty; S E Moss; M D Waterfield; M J Crumpton
Journal:  EMBO J       Date:  1988-01       Impact factor: 11.598

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  6 in total

Review 1.  A compilation of cellular transcription factor interactions with the HIV-1 LTR promoter.

Authors:  L A Pereira; K Bentley; A Peeters; M J Churchill; N J Deacon
Journal:  Nucleic Acids Res       Date:  2000-02-01       Impact factor: 16.971

2.  An EMSA-based method for determining the molecular weight of a protein--DNA complex.

Authors:  K Orchard; G E May
Journal:  Nucleic Acids Res       Date:  1993-07-11       Impact factor: 16.971

3.  Promoter control of translation in Xenopus oocytes.

Authors:  N Gunkel; M Braddock; A M Thorburn; M Muckenthaler; A J Kingsman; S M Kingsman
Journal:  Nucleic Acids Res       Date:  1995-02-11       Impact factor: 16.971

4.  Interactions of the transcription factor AP-1 with the long terminal repeat of different human immunodeficiency virus type 1 strains in Jurkat, glial, and neuronal cells.

Authors:  F Canonne-Hergaux; D Aunis; E Schaeffer
Journal:  J Virol       Date:  1995-11       Impact factor: 5.103

5.  NF-IL6-mediated transcriptional activation of the long terminal repeat of the human immunodeficiency virus type 1.

Authors:  V M Tesmer; A Rajadhyaksha; J Babin; M Bina
Journal:  Proc Natl Acad Sci U S A       Date:  1993-08-01       Impact factor: 11.205

6.  HIV-1 Promoter Single Nucleotide Polymorphisms Are Associated with Clinical Disease Severity.

Authors:  Michael R Nonnemacher; Vanessa Pirrone; Rui Feng; Brian Moldover; Shendra Passic; Benjamas Aiamkitsumrit; Will Dampier; Adam Wojno; Evelyn Kilareski; Brandon Blakey; Tse-Sheun Jade Ku; Sonia Shah; Neil T Sullivan; Jeffrey M Jacobson; Brian Wigdahl
Journal:  PLoS One       Date:  2016-04-21       Impact factor: 3.240

  6 in total

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