Literature DB >> 1533884

Activation of the human immunodeficiency virus type 1 enhancer is not dependent on NFAT-1.

D M Markovitz1, M C Hannibal, M J Smith, R Cossman, G J Nabel.   

Abstract

The function of a putative NFAT-1 site in the human immunodeficiency virus type 1 enhancer has been analyzed. Activation by the T-cell antigen receptor is minimal in Jurkat cells and is mediated by the kappa B sites. The putative NFAT-1 region is not required for the response to anti-CD3 or to mitogens in T-cell, B-cell, or monocyte/macrophage leukemia lines, nor is it a cis-acting negative regulatory element.

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Year:  1992        PMID: 1533884      PMCID: PMC241190     

Source DB:  PubMed          Journal:  J Virol        ISSN: 0022-538X            Impact factor:   5.103


  30 in total

1.  Sequence-specific binding of human Ets-1 to the T cell receptor alpha gene enhancer.

Authors:  I C Ho; N K Bhat; L R Gottschalk; T Lindsten; C B Thompson; T S Papas; J M Leiden
Journal:  Science       Date:  1990-11-09       Impact factor: 47.728

2.  cis-acting sequences required for inducible interleukin-2 enhancer function bind a novel Ets-related protein, Elf-1.

Authors:  C B Thompson; C Y Wang; I C Ho; P R Bohjanen; B Petryniak; C H June; S Miesfeldt; L Zhang; G J Nabel; B Karpinski
Journal:  Mol Cell Biol       Date:  1992-03       Impact factor: 4.272

3.  Linker-scanning mutational analysis of the transcriptional activity of the human immunodeficiency virus type 1 long terminal repeat.

Authors:  S L Zeichner; J Y Kim; J C Alwine
Journal:  J Virol       Date:  1991-05       Impact factor: 5.103

Review 4.  Regulation of HIV-1 gene expression.

Authors:  W C Greene
Journal:  Annu Rev Immunol       Date:  1990       Impact factor: 28.527

5.  The macrophage and B cell-specific transcription factor PU.1 is related to the ets oncogene.

Authors:  M J Klemsz; S R McKercher; A Celada; C Van Beveren; R A Maki
Journal:  Cell       Date:  1990-04-06       Impact factor: 41.582

6.  Inducible nuclear factor binding to the kappa B elements of the human immunodeficiency virus enhancer in T cells can be blocked by cyclosporin A in a signal-dependent manner.

Authors:  A Schmidt; L Hennighausen; U Siebenlist
Journal:  J Virol       Date:  1990-08       Impact factor: 5.103

7.  Differences in transcriptional enhancers of HIV-1 and HIV-2. Response to T cell activation signals.

Authors:  S E Tong-Starksen; T M Welsh; B M Peterlin
Journal:  J Immunol       Date:  1990-12-15       Impact factor: 5.422

8.  Differential regulation of human immunodeficiency viruses (HIVs): a specific regulatory element in HIV-2 responds to stimulation of the T-cell antigen receptor.

Authors:  D M Markovitz; M Hannibal; V L Perez; C Gauntt; T M Folks; G J Nabel
Journal:  Proc Natl Acad Sci U S A       Date:  1990-12       Impact factor: 11.205

9.  Stimulation of a human T-cell clone with anti-CD3 or tumor necrosis factor induces NF-kappa B translocation but not human immunodeficiency virus 1 enhancer-dependent transcription.

Authors:  U Hazan; D Thomas; J Alcami; F Bachelerie; N Israel; H Yssel; J L Virelizier; F Arenzana-Seisdedos
Journal:  Proc Natl Acad Sci U S A       Date:  1990-10       Impact factor: 11.205

10.  Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

Authors:  C M Gorman; L F Moffat; B H Howard
Journal:  Mol Cell Biol       Date:  1982-09       Impact factor: 4.272

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  18 in total

1.  Modulation of HIV transcription by CD8(+) cells is mediated via multiple elements of the long terminal repeat.

Authors:  D M Maslove; L W Ni; N C Hawley-Foss; A D Badley; K F Copeland
Journal:  Clin Exp Immunol       Date:  2001-07       Impact factor: 4.330

Review 2.  Regulation of HIV-1 transcription.

Authors:  K A Roebuck; M Saifuddin
Journal:  Gene Expr       Date:  1999

3.  The sequence and structure of the 3' arm of the first stem-loop of the human immunodeficiency virus type 2 trans-activation responsive region mediate Tat-2 transactivation.

Authors:  C Browning; J M Hilfinger; S Rainier; V Lin; S Hedderwick; M Smith; D M Markovitz
Journal:  J Virol       Date:  1997-10       Impact factor: 5.103

4.  Physical interactions between Ets and NF-kappaB/NFAT proteins play an important role in their cooperative activation of the human immunodeficiency virus enhancer in T cells.

Authors:  A G Bassuk; R T Anandappa; J M Leiden
Journal:  J Virol       Date:  1997-05       Impact factor: 5.103

5.  Inhibition of phosphodiesterase type IV suppresses human immunodeficiency virus type 1 replication and cytokine production in primary T cells: involvement of NF-kappaB and NFAT.

Authors:  J Navarro; C Punzón; J L Jiménez; E Fernández-Cruz; A Pizarro; M Fresno; M A Muñoz-Fernández
Journal:  J Virol       Date:  1998-06       Impact factor: 5.103

6.  DEK, an autoantigen involved in a chromosomal translocation in acute myelogenous leukemia, binds to the HIV-2 enhancer.

Authors:  G K Fu; G Grosveld; D M Markovitz
Journal:  Proc Natl Acad Sci U S A       Date:  1997-03-04       Impact factor: 11.205

7.  Differential activation of human immunodeficiency virus type 1 and 2 transcription by specific T-cell activation signals.

Authors:  M C Hannibal; D M Markovitz; N Clark; G J Nabel
Journal:  J Virol       Date:  1993-08       Impact factor: 5.103

8.  Human T cell transcription factor GATA-3 stimulates HIV-1 expression.

Authors:  Z Yang; J D Engel
Journal:  Nucleic Acids Res       Date:  1993-06-25       Impact factor: 16.971

9.  Activation of the human T-cell leukemia virus type I enhancer is mediated by binding sites for Elf-1 and the pets factor.

Authors:  N M Clark; M J Smith; J M Hilfinger; D M Markovitz
Journal:  J Virol       Date:  1993-09       Impact factor: 5.103

Review 10.  Regulation of HIV-1 transcription in cells of the monocyte-macrophage lineage.

Authors:  Evelyn M Kilareski; Sonia Shah; Michael R Nonnemacher; Brian Wigdahl
Journal:  Retrovirology       Date:  2009-12-23       Impact factor: 4.602

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