Literature DB >> 23979742

New structure of phage-related islands carrying fusB and a virulence gene in fusidic acid-resistant Staphylococcus epidermidis.

Hsiao-Jan Chen1, Ya-Chun Chang, Jui-Chang Tsai, Wei-Chun Hung, Yu-Tzu Lin, Shang-Jie You, Sung-Pin Tseng, Lee-Jene Teng.   

Abstract

Nucleotide sequencing of the fusB-flanking regions in two fusidic acid-resistant Staphylococcus epidermidis isolates with the type IV aj1-leader peptide (LP)-fusB structure (lacking aj1) revealed that their fusB gene was located on novel phage-related islands inserted downstream of smpB and are here referred to as SeRIfusB-3692 and SePIfusB-857. The novel SePIfusB-857 structure was followed by SeCI857, forming a composite pathogenicity island which contained a putative virulence gene, vapE. The linkage of fusB and vapE may contribute to bacterial adaption.

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Year:  2013        PMID: 23979742      PMCID: PMC3811319          DOI: 10.1128/AAC.01433-13

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN: 0066-4804            Impact factor:   5.191


  17 in total

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2.  Distribution of Staphylococcal Cassette Chromosome (SCC) mec Element Types in Fusidic Acid-Resistant Staphylococcus epidermidis and Identification of a Novel SCC7684 Element.

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Review 9.  Phage satellites and their emerging applications in biotechnology.

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10.  Skin Commensal Staphylococci May Act as Reservoir for Fusidic Acid Resistance Genes.

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