Literature DB >> 23970350

A novel approach to quantifying ciliary physiology: microfluidic mixing driven by a ciliated biological surface.

Stephan Jonas1, Elaine Zhou, Engin Deniz, Brendan Huang, Kenny Chandrasekera, Dipankan Bhattacharya, Yu Wu, Rong Fan, Thomas M Deserno, Mustafa K Khokha, Michael A Choma.   

Abstract

From the lungs to the central nervous system, cilia-driven fluid flow plays a fundamental role in many facets of life. Yet, there are few quantitative methods for analysing the function of ciliated surfaces. Here, we report a novel microfluidic approach for quantifying the performance of a ciliated surface using mixing performance as an integrated readout.

Entities:  

Mesh：

Year:  2013        PMID： 23970350      PMCID： PMC3856250          DOI： 10.1039/c3lc50571e

Source DB:  PubMed          Journal:  Lab Chip        ISSN： 1473-0189            Impact factor:   6.799


  16 in total

Review 1.  Mucus clearance as a primary innate defense mechanism for mammalian airways.

Authors:  Michael R Knowles; Richard C Boucher
Journal:  J Clin Invest       Date:  2002-03       Impact factor: 14.808

2.  Dynamics of enhanced tracer diffusion in suspensions of swimming eukaryotic microorganisms.

Authors:  Kyriacos C Leptos; Jeffrey S Guasto; J P Gollub; Adriana I Pesci; Raymond E Goldstein
Journal:  Phys Rev Lett       Date:  2009-11-05       Impact factor: 9.161

3.  Heterotaxia, congenital heart disease, and primary ciliary dyskinesia.

Authors:  Martina Brueckner
Journal:  Circulation       Date:  2007-06-05       Impact factor: 29.690

4.  A positive feedback mechanism governs the polarity and motion of motile cilia.

Authors:  Brian Mitchell; Richard Jacobs; Julie Li; Shu Chien; Chris Kintner
Journal:  Nature       Date:  2007-04-22       Impact factor: 49.962

5.  Low-cost rapid prototyping of flexible microfluidic devices using a desktop digital craft cutter.

Authors:  Po Ki Yuen; Vasiliy N Goral
Journal:  Lab Chip       Date:  2009-11-24       Impact factor: 6.799

Review 6.  Understanding ciliated epithelia: the power of Xenopus.

Authors:  M E Werner; B J Mitchell
Journal:  Genesis       Date:  2011-12-27       Impact factor: 2.487

7.  Impact of genetic diagnosis on clinical management of patients with congenital heart disease: cilia point the way.

Authors:  Martina Brueckner
Journal:  Circulation       Date:  2012-04-12       Impact factor: 29.690

Review 8.  Making sense of cilia in disease: the human ciliopathies.

Authors:  Kate Baker; Philip L Beales
Journal:  Am J Med Genet C Semin Med Genet       Date:  2009-11-15       Impact factor: 3.908

9.  Monitoring airway mucus flow and ciliary activity with optical coherence tomography.

Authors:  Amy L Oldenburg; Raghav K Chhetri; David B Hill; Brian Button
Journal:  Biomed Opt Express       Date:  2012-08-01       Impact factor: 3.732

10.  Microfluidic characterization of cilia-driven fluid flow using optical coherence tomography-based particle tracking velocimetry.

Authors:  Stephan Jonas; Dipankan Bhattacharya; Mustafa K Khokha; Michael A Choma
Journal:  Biomed Opt Express       Date:  2011-06-22       Impact factor: 3.732
View more
  2 in total

1.  Three-dimensional, three-vector-component velocimetry of cilia-driven fluid flow using correlation-based approaches in optical coherence tomography.

Authors:  Brendan K Huang; Ute A Gamm; Vineet Bhandari; Mustafa K Khokha; Michael A Choma
Journal:  Biomed Opt Express       Date:  2015-08-24       Impact factor: 3.732

Review 2.  Microscale imaging of cilia-driven fluid flow.

Authors:  Brendan K Huang; Michael A Choma
Journal:  Cell Mol Life Sci       Date:  2014-11-23       Impact factor: 9.261
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.