| Literature DB >> 23969482 |
Gareth S Owen1, George Szmukler, Genevra Richardson, Anthony S David, Vanessa Raymont, Fabian Freyenhagen, Wayne Martin, Matthew Hotopf.
Abstract
BACKGROUND: Is the nature of decision-making capacity (DMC) for treatment significantly different in medical and psychiatric patients? AIMS: To compare the abilities relevant to DMC for treatment in medical and psychiatric patients who are able to communicate a treatment choice.Entities:
Mesh:
Year: 2013 PMID: 23969482 PMCID: PMC3844898 DOI: 10.1192/bjp.bp.112.123976
Source DB: PubMed Journal: Br J Psychiatry ISSN: 0007-1250 Impact factor: 9.319
Demographic and clinical characteristics, and principal diagnoses (ICD-10 categories)[18] of the two samples
| Medical hospital | Psychiatric hospital | |
|---|---|---|
| Age, years: mean (s.d.) | 62.7 (20.5) | 39.6 (11.5) |
| Male, | 61 (49) | 107 (65) |
| Ethnicity, | ||
| White | 105 (84) | 89 (54) |
| Black | 18 (14) | 65 (40) |
| Other | 2 (2) | 10 (6) |
| Married/partner, | 37 (30) | 24 (15) |
| Living situation, | ||
| Alone | 58 (46) | 73 (45) |
| With family | 57 (46) | 50 (30) |
| Supported accommodation | 9 (7) | 22 (13) |
| Other | 1 (1) | 19 (12) |
| Without DMC, | 37 (30) | 85 (52) |
| Cardiac | 34 (27) | |
| Respiratory | 30 (24) | |
| Infectious | 19 (15) | |
| Neurological | 7 (6) | |
| Gastrointestinal | 6 (5) | |
| Alcohol-related | 7 (6) | |
| Haematological | 3 (2) | |
| Cancer | 2 (2) | |
| Endocrine | 2 (2) | |
| Unknown medical disorder | 15 (12) | |
| Psychotic episode | 40 (24) | |
| Schizophrenia or related | 34 (21) | |
| Unipolar depression | 39 (24) | |
| Bipolar affective disorder | ||
| Manic episode | 17 (10) | |
| Depressive episode | 6 (4) | |
| Personality disorder | 14 (9) | |
| Post-traumatic stress disorder | 3 (2) | |
| Organic brain syndrome | 4 (2) | |
| Other psychiatric disorder | 7 (4) |
DMC, decision-making capacity.
Descriptive statistics of legal abilities by hospital and decision-making capacity
| Medical hospital | Psychiatric hospital | |||||
|---|---|---|---|---|---|---|
| Decision-making capacity, median (IQR) | Decision-making capacity, median (IQR) | |||||
| MacCAT-T ability | Scale range | With ( | Without ( | Scale range | With ( | Without ( |
| Understanding | 0-4 | 4 (3-4) | 2 (1-4) | 0-6 | 6 (5-6) | 4 (2-5) |
| Appreciation | 0-4 | 4 (3-4) | 2 (2-3) | 0-4 | 4 (3-4) | 1 (0-2) |
| Reasoning | 0-8 | 5 (4-6) | 1 (1-2) | 0-8 | 8 (7-8) | 5 (3-6) |
Each MacArthur Competence Assessment Tool - Treatment (MacCAT-T) ability was significantly lower in people without decision-making capacity compared with people with it (Mann-Whitney test; all P-values <0.0001).
Patients with poor v. good scores on understanding
| Medical hospital, | Psychiatric hospital, | |||||
|---|---|---|---|---|---|---|
| Total | With DMC | Without DMC | Total | With DMC | Without DMC | |
| Poor understanding, total | 31 (25) | 6 (19) | 25 (81) | 40 (24) | 3 (7) | 37 (93) |
| Poor score on appreciation | 1 (17) | 17 (68) | 1 (33) | 35 (95) | ||
| Poor score on reasoning | 2 (33) | 25 (100) | 0 (0) | 29 (78) | ||
| Poor score on appreciation and reasoning | 0 (0) | 17 (68) | 0 (0) | 27 (73) | ||
| Good understanding, total | 94 (75) | 82 (87) | 12 (13) | 124 (76) | 76 (61) | 48 (39) |
| Poor score on appreciation | 2 (2) | 2 (17) | 4 (1) | 45 (94) | ||
| Poor score on reasoning | 25 (30) | 12 (100) | 0 (0) | 8 (17) | ||
DMC, decision-making capacity.
A poor score for each ability was defined as less than or equal to the mid-point of each scale and a good score was defined as more than the mid-point of the scale.
Sensitivities and specificities of poor appreciation and poor reasoning as ‘tests’ for decision-making capacity in patients with good scores on understanding
| Medical hospital ( | Psychiatric hospital ( | |||
|---|---|---|---|---|
| Sensitivity | Specificity | Sensitivity | Specificity | |
| Poor score on appreciation | 0.17 | 0.98 | 0.94 | 0.95 |
| Poor score on reasoning | 1.00 | 0.70 | 0.17 | 1.00 |
Good score on understanding was defined as more than the mid-point of the scale (i.e. >3 in the psychiatric hospital and >2 in the medical hospital).
Hospital comparison of receiver operating characteristic (ROC) areas for appreciation and reasoning as tests of decision-making capacity in patients with good understanding
| Medical hospital | Psychiatric hospital | |||||
|---|---|---|---|---|---|---|
| ROC area under curve | ROC area under curve | χ2 (d.f. = 1) | ||||
| Appreciation | 94 | 0.69 | 124 | 0.97 | 11.83 | 0.0006 |
| Reasoning | 94 | 0.95 | 122 | 0.84 | 5.22 | 0.02 |
Fig. 1Patients able to express a choice but without decision-making capacity.
Examples from the MacCAT-T of how appreciation and reasoning abilities are probed, with guidelines on inability
| Ability | Example probe | Guidelines on inability |
| Appreciation | ‘That is what we [your doctors] think is the problem in your case. If you have any reason to doubt that, I’d like you to tell me so. What do you think?’ | Patient clearly does not agree that he or she has the disclosed disorder, with reasoning based on a delusional premise or some other belief that seriously distorts reality and does not have a reasonable basis in the patient’s cultural or religious background. |
| OR | ||
| Patient believes that the symptoms are related to circumstances other than a medical/psychiatric disorder (e.g. psychotic symptoms seen as consequences of work-related stress). | ||
| OR | ||
| Patient clearly disagrees with symptoms or disorder, but with no comprehensible explanation offered. | ||
| ‘You might or might not decide that this is the treatment you want - we’ll talk about that later. But do you think it’s possible that this treatment might be of benefit to you?’ | Patient acknowledges at least some potential for the treatment to produce some benefit, but for reasons that appear to be based on a delusional premise or a serious distortion of reality. | |
| OR | ||
| Patient does not believe that the treatment has the potential to produce any benefit, and offers reasons that appear to be delusional or a serious distortion of reality. | ||
| Reasoning | ‘You think that treatment X might be best. Tell me what it is that makes that seem better than the others.’ | Patient can make no comparative statements. |