Literature DB >> 23956498

Microfluidic jet injection for delivering macromolecules into cells.

A Adamo1, O Roushdy, R Dokov, A Sharei, K F Jensen.   

Abstract

We present a microfluidic based injection system designed to achieve intracellular delivery of macromolecules by directing a picoliter-jet of a solution towards individual cells. After discussing the concept, we present design specification and criteria, elucidate performance and discuss results. The method has the potential to be quantitative and high throughput, overcoming limitations of current intracellular delivery protocols.

Entities:  

Year:  2013        PMID: 23956498      PMCID: PMC3744198          DOI: 10.1088/0960-1317/23/3/035026

Source DB:  PubMed          Journal:  J Micromech Microeng        ISSN: 0960-1317            Impact factor:   1.881


  15 in total

Review 1.  Gene delivery using physical methods: an overview.

Authors:  Te-hui W Chou; Subhabrata Biswas; Shan Lu
Journal:  Methods Mol Biol       Date:  2004

2.  Gene delivery to mammalian cells by microinjection.

Authors:  Robert King
Journal:  Methods Mol Biol       Date:  2004

Review 3.  Hydro-Jet technology in urologic surgery.

Authors:  Bijan Shekarriz
Journal:  Expert Rev Med Devices       Date:  2005-05       Impact factor: 3.166

4.  Sonoporation from jetting cavitation bubbles.

Authors:  Claus-Dieter Ohl; Manish Arora; Roy Ikink; Nico de Jong; Michel Versluis; Michael Delius; Detlef Lohse
Journal:  Biophys J       Date:  2006-09-01       Impact factor: 4.033

Review 5.  Nonviral gene delivery: what we know and what is next.

Authors:  Xiang Gao; Keun-Sik Kim; Dexi Liu
Journal:  AAPS J       Date:  2007-03-23       Impact factor: 4.009

6.  Sonoporation of suspension cells with a single cavitation bubble in a microfluidic confinement.

Authors:  Séverine Le Gac; Ed Zwaan; Albert van den Berg; Claus-Dieter Ohl
Journal:  Lab Chip       Date:  2007-09-14       Impact factor: 6.799

Review 7.  Dermal and transdermal drug delivery systems: current and future prospects.

Authors:  Marc B Brown; Gary P Martin; Stuart A Jones; Franklin K Akomeah
Journal:  Drug Deliv       Date:  2006 May-Jun       Impact factor: 6.419

8.  Microfluidic based single cell microinjection.

Authors:  Andrea Adamo; Klavs F Jensen
Journal:  Lab Chip       Date:  2008-07-01       Impact factor: 6.799

9.  Dynamic control of needle-free jet injection.

Authors:  Jeanne C Stachowiak; Thomas H Li; Anubhav Arora; Samir Mitragotri; Daniel A Fletcher
Journal:  J Control Release       Date:  2009-01-21       Impact factor: 9.776

Review 10.  Gene transfer by retroviral vectors: an overview.

Authors:  Nikunj Somia
Journal:  Methods Mol Biol       Date:  2004
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  6 in total

1.  Continuous-wave laser generated jets for needle free applications.

Authors:  Carla Berrospe-Rodriguez; Claas Willem Visser; Stefan Schlautmann; Ruben Ramos-Garcia; David Fernandez Rivas
Journal:  Biomicrofluidics       Date:  2016-01-13       Impact factor: 2.800

Review 2.  Physical methods for intracellular delivery: practical aspects from laboratory use to industrial-scale processing.

Authors:  J Mark Meacham; Kiranmai Durvasula; F Levent Degertekin; Andrei G Fedorov
Journal:  J Lab Autom       Date:  2013-06-27

Review 3.  Microfluidic mechanoporation for cellular delivery and analysis.

Authors:  Pulasta Chakrabarty; Pallavi Gupta; Kavitha Illath; Srabani Kar; Moeto Nagai; Fan-Gang Tseng; Tuhin Subhra Santra
Journal:  Mater Today Bio       Date:  2021-12-20

Review 4.  Microfluidic and Nanofluidic Intracellular Delivery.

Authors:  Jeongsoo Hur; Aram J Chung
Journal:  Adv Sci (Weinh)       Date:  2021-06-06       Impact factor: 16.806

Review 5.  Transdermal Drug Delivery: Innovative Pharmaceutical Developments Based on Disruption of the Barrier Properties of the stratum corneum.

Authors:  Ahlam Zaid Alkilani; Maelíosa T C McCrudden; Ryan F Donnelly
Journal:  Pharmaceutics       Date:  2015-10-22       Impact factor: 6.321

6.  Enhanced gene delivery in tumor cells using chemical carriers and mechanical loadings.

Authors:  Amin Hadi; Abbas Rastgoo; Nooshin Haghighipour; Azam Bolhassani; Fatemeh Asgari; Sepehr Soleymani
Journal:  PLoS One       Date:  2018-12-28       Impact factor: 3.240

  6 in total

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