Literature DB >> 26858816

Continuous-wave laser generated jets for needle free applications.

Carla Berrospe-Rodriguez1, Claas Willem Visser2, Stefan Schlautmann3, Ruben Ramos-Garcia1, David Fernandez Rivas3.   

Abstract

We designed and built a microfluidic device for the generation of liquid jets produced by thermocavitation. A continuous wave (CW) laser was focused inside a micro-chamber filled with a light-absorbing solution to create a rapidly expanding vapor bubble. The chamber is connected to a micro-channel which focuses and ejects the liquid jet through the exit. The bubble growth and the jet velocity were measured as a function of the devices geometry (channel diameter D and chamber width A). The fastest jets were those for relatively large chamber size with respect to the channel diameter. Elongated and focused jets up to 29 m/s for a channel diameter of [Formula: see text] and chamber size of [Formula: see text] were obtained. The proposed CW laser-based device is potentially a compact option for a practical and commercially feasible needle-free injector.

Year:  2016        PMID: 26858816      PMCID: PMC4714984          DOI: 10.1063/1.4940038

Source DB:  PubMed          Journal:  Biomicrofluidics        ISSN: 1932-1058            Impact factor:   2.800


  26 in total

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  3 in total

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