Literature DB >> 23949572

Factors influencing organizational adoption and implementation of clinical genetic services.

Alison B Hamilton1, Sabine Oishi2, Elizabeth M Yano3, Cynthia E Gammage2, Nell J Marshall3, Maren T Scheuner4.   

Abstract

PURPOSE: We sought to identify characteristics of genetic services that facilitate or hinder adoption.
METHODS: We conducted semi-structured key informant interviews in five clinical specialties (primary care, medical oncology, neurology, cardiology, pathology/laboratory medicine) within 13 Veterans Administration facilities.
RESULTS: Genetic services (defined as genetic testing and consultation) were not typically characterized by informants (n = 64) as advantageous for their facilities or their patients; compatible with organizational norms of low cost and high clinical impact; or applicable to patient populations or norms of clinical care. Furthermore, genetic services had not been systematically adopted in most facilities because of their complexity: knowledge of and expertise on genetic testing was limited, and organizational barriers to utilization of genetic services were formidable. The few facilities that had some success with implementation of genetic services had knowledgeable clinicians interested in developing services and organizational-level facilitators such as accessible genetic test-ordering processes.
CONCLUSION: Adoption and implementation of genetic services will require a multilevel effort that includes education of providers and administrators, opportunities for observing the benefits of genetic medicine, strategies for reducing the complexity of genomic medicine, expanded strategies for accessing genetics expertise and streamlining utilization, and resources dedicated to assessing the value of genetic information for the outcomes that matter to health-care organizations.

Entities:  

Mesh:

Year:  2013        PMID: 23949572     DOI: 10.1038/gim.2013.101

Source DB:  PubMed          Journal:  Genet Med        ISSN: 1098-3600            Impact factor:   8.822


  27 in total

1.  A theory-informed systematic review of clinicians' genetic testing practices.

Authors:  Jean L Paul; Hanna Leslie; Alison H Trainer; Clara Gaff
Journal:  Eur J Hum Genet       Date:  2018-06-11       Impact factor: 4.246

2.  Primary care providers' experiences with and perceptions of personalized genomic medicine.

Authors:  June C Carroll; Tutsirai Makuwaza; Donna P Manca; Nicolette Sopcak; Joanne A Permaul; Mary Ann O'Brien; Ruth Heisey; Elizabeth A Eisenhauer; Julie Easley; Monika K Krzyzanowska; Baukje Miedema; Sandhya Pruthi; Carol Sawka; Nancy Schneider; Jonathan Sussman; Robin Urquhart; Catarina Versaevel; Eva Grunfeld
Journal:  Can Fam Physician       Date:  2016-10       Impact factor: 3.275

3.  Developing a framework for implementation of genetic services: learning from examples of testing for monogenic forms of common diseases.

Authors:  Tessel Rigter; Lidewij Henneman; Jacqueline E W Broerse; Maggie Shepherd; Ignacio Blanco; Ulf Kristoffersson; Martina C Cornel
Journal:  J Community Genet       Date:  2014-06-04

4.  Physician Experiences and Understanding of Genomic Sequencing in Oncology.

Authors:  Caroline M Weipert; Kerry A Ryan; Jessica N Everett; Beverly M Yashar; Arul M Chinnaiyan; J Scott Roberts; Raymond De Vries; Brian J Zikmund-Fisher; Victoria M Raymond
Journal:  J Genet Couns       Date:  2017-08-24       Impact factor: 2.537

5.  Clinical pharmacogenetics implementation: approaches, successes, and challenges.

Authors:  Kristin W Weitzel; Amanda R Elsey; Taimour Y Langaee; Benjamin Burkley; David R Nessl; Aniwaa Owusu Obeng; Benjamin J Staley; Hui-Jia Dong; Robert W Allan; J Felix Liu; Rhonda M Cooper-Dehoff; R David Anderson; Michael Conlon; Michael J Clare-Salzler; David R Nelson; Julie A Johnson
Journal:  Am J Med Genet C Semin Med Genet       Date:  2014-03-10       Impact factor: 3.908

Review 6.  Points to Consider: Ethical, Legal, and Psychosocial Implications of Genetic Testing in Children and Adolescents.

Authors:  Jeffrey R Botkin; John W Belmont; Jonathan S Berg; Benjamin E Berkman; Yvonne Bombard; Ingrid A Holm; Howard P Levy; Kelly E Ormond; Howard M Saal; Nancy B Spinner; Benjamin S Wilfond; Joseph D McInerney
Journal:  Am J Hum Genet       Date:  2015-07-02       Impact factor: 11.025

Review 7.  Precision Medicine at the University of Alabama at Birmingham: Laying the Foundational Processes Through Implementation of Genotype-Guided Antiplatelet Therapy.

Authors:  S Harada; Y Zhou; S Duncan; A R Armstead; G M Coshatt; C Dillon; B C Brott; J Willig; J A Alsip; W B Hillegass; N A Limdi
Journal:  Clin Pharmacol Ther       Date:  2017-06-01       Impact factor: 6.875

8.  Qualitative methods in implementation research: An introduction.

Authors:  Alison B Hamilton; Erin P Finley
Journal:  Psychiatry Res       Date:  2019-08-10       Impact factor: 3.222

9.  Integrating Germline Genetics Into Precision Oncology Practice in the Veterans Health Administration: Challenges and Opportunities.

Authors:  Maren T Scheuner; Kenute Myrie; Jane Peredo; Lori Hoffman-Hogg; Margaret Lundquist; Stephanie L Guerra; Douglas Ball
Journal:  Fed Pract       Date:  2020-08

10.  The value of genetic testing: beyond clinical utility.

Authors:  Barbara Lerner; Nell Marshall; Sabine Oishi; Andrew Lanto; Martin Lee; Alison B Hamilton; Elizabeth M Yano; Maren T Scheuner
Journal:  Genet Med       Date:  2016-12-15       Impact factor: 8.822

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