Literature DB >> 23948583

New and TALENted genome engineering toolbox.

Jarryd M Campbell1, Katherine A Hartjes, Timothy J Nelson, Xiaolei Xu, Stephen C Ekker.   

Abstract

Recent advances in the burgeoning field of genome engineering are accelerating the realization of personalized therapeutics for cardiovascular disease. In the postgenomic era, sequence-specific gene-editing tools enable the functional analysis of genetic alterations implicated in disease. In partnership with high-throughput model systems, efficient gene manipulation provides an increasingly powerful toolkit to study phenotypes associated with patient-specific genetic defects. Herein, this review emphasizes the latest developments in genome engineering and how applications within the field are transforming our understanding of personalized medicine with an emphasis on cardiovascular diseases.

Entities:  

Keywords:  TALENs; cardiovascular disease modeling; genome engineering; induced pluripotent stem cells; zebrafish

Mesh：

Substances：

Year:  2013        PMID： 23948583      PMCID： PMC3965580          DOI： 10.1161/CIRCRESAHA.113.301765

Source DB:  PubMed          Journal:  Circ Res        ISSN： 0009-7330            Impact factor:   17.367


  157 in total

Review 1.  Doxorubicin in experimental and clinical heart failure.

Authors:  Stefan Christiansen; Rüdiger Autschbach
Journal:  Eur J Cardiothorac Surg       Date:  2006-08-08       Impact factor: 4.191

2.  High-resolution in situ hybridization to whole-mount zebrafish embryos.

Authors:  Christine Thisse; Bernard Thisse
Journal:  Nat Protoc       Date:  2008       Impact factor: 13.491

3.  Site-specific gene correction of a point mutation in human iPS cells derived from an adult patient with sickle cell disease.

Authors:  Jizhong Zou; Prashant Mali; Xiaosong Huang; Sarah N Dowey; Linzhao Cheng
Journal:  Blood       Date:  2011-08-31       Impact factor: 22.113

4.  Targeted genome editing across species using ZFNs and TALENs.

Authors:  Andrew J Wood; Te-Wen Lo; Bryan Zeitler; Catherine S Pickle; Edward J Ralston; Andrew H Lee; Rainier Amora; Jeffrey C Miller; Elo Leung; Xiangdong Meng; Lei Zhang; Edward J Rebar; Philip D Gregory; Fyodor D Urnov; Barbara J Meyer
Journal:  Science       Date:  2011-06-23       Impact factor: 47.728

5.  Cell line-dependent differentiation of induced pluripotent stem cells into cardiomyocytes in mice.

Authors:  Shinji Kaichi; Koji Hasegawa; Tomohide Takaya; Noritaka Yokoo; Takahiro Mima; Teruhisa Kawamura; Tatsuya Morimoto; Koh Ono; Shiro Baba; Hiraku Doi; Shinya Yamanaka; Tatsutoshi Nakahata; Toshio Heike
Journal:  Cardiovasc Res       Date:  2010-06-14       Impact factor: 10.787

6.  Highly efficient generation of heritable zebrafish gene mutations using homo- and heterodimeric TALENs.

Authors:  Lindsay Cade; Deepak Reyon; Woong Y Hwang; Shengdar Q Tsai; Samir Patel; Cyd Khayter; J Keith Joung; Jeffry D Sander; Randall T Peterson; Jing-Ruey Joanna Yeh
Journal:  Nucleic Acids Res       Date:  2012-06-07       Impact factor: 16.971

7.  Modularly assembled designer TAL effector nucleases for targeted gene knockout and gene replacement in eukaryotes.

Authors:  Ting Li; Sheng Huang; Xuefeng Zhao; David A Wright; Susan Carpenter; Martin H Spalding; Donald P Weeks; Bing Yang
Journal:  Nucleic Acids Res       Date:  2011-03-31       Impact factor: 16.971

8.  The zebrafish heart regenerates after cryoinjury-induced myocardial infarction.

Authors:  Fabian Chablais; Julia Veit; Gregor Rainer; Anna Jaźwińska
Journal:  BMC Dev Biol       Date:  2011-04-07       Impact factor: 1.978

9.  Cardiomyocytes generated from CPVTD307H patients are arrhythmogenic in response to β-adrenergic stimulation.

Authors:  Atara Novak; Lili Barad; Naama Zeevi-Levin; Revital Shick; Ronit Shtrichman; Avraham Lorber; Joseph Itskovitz-Eldor; Ofer Binah
Journal:  J Cell Mol Med       Date:  2012-03       Impact factor: 5.310

10.  Genome editing with RNA-guided Cas9 nuclease in zebrafish embryos.

Authors:  Nannan Chang; Changhong Sun; Lu Gao; Dan Zhu; Xiufei Xu; Xiaojun Zhu; Jing-Wei Xiong; Jianzhong Jeff Xi
Journal:  Cell Res       Date:  2013-03-26       Impact factor: 25.617
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  25 in total

1.  The CRISPR road: from bench to bedside on an RNA-guided path.

Authors:  Benjamin Garcia-Bloj; Colette Moses; Pilar Blancafort
Journal:  Ann Transl Med       Date:  2015-08

Review 2.  A tale of two models: mouse and zebrafish as complementary models for lymphatic studies.

Authors:  Jun-Dae Kim; Suk-Won Jin
Journal:  Mol Cells       Date:  2014-05-23       Impact factor: 5.034

Review 3.  Understanding cardiac sarcomere assembly with zebrafish genetics.

Authors:  Jingchun Yang; Yu-Huan Shih; Xiaolei Xu
Journal:  Anat Rec (Hoboken)       Date:  2014-09       Impact factor: 2.064

Review 4.  Zebrafish as a model to investigate CNS myelination.

Authors:  Marnie A Preston; Wendy B Macklin
Journal:  Glia       Date:  2014-09-27       Impact factor: 7.452

5.  Cardiac transcriptome and dilated cardiomyopathy genes in zebrafish.

Authors:  Yu-Huan Shih; Yuji Zhang; Yonghe Ding; Christian A Ross; Hu Li; Timothy M Olson; Xiaolei Xu
Journal:  Circ Cardiovasc Genet       Date:  2015-01-11

6.  Using engineered endonucleases to create knockout and knockin zebrafish models.

Authors:  Victoria M Bedell; Stephen C Ekker
Journal:  Methods Mol Biol       Date:  2015

7.  Exon- and contraction-dependent functions of titin in sarcomere assembly.

Authors:  Yu-Huan Shih; Alexey V Dvornikov; Ping Zhu; Xiao Ma; Maengjo Kim; Yonghe Ding; Xiaolei Xu
Journal:  Development       Date:  2016-11-11       Impact factor: 6.868

Review 8.  Cellular therapy for liver disease.

Authors:  Robert C Huebert; Jorge Rakela
Journal:  Mayo Clin Proc       Date:  2014-03       Impact factor: 7.616

9.  Selection via pluripotency-related transcriptional screen minimizes the influence of somatic origin on iPSC differentiation propensity.

Authors:  Katherine A Hartjes; Xing Li; Almudena Martinez-Fernandez; Alexa J Roemmich; Brandon T Larsen; Andre Terzic; Timothy J Nelson
Journal:  Stem Cells       Date:  2014-09       Impact factor: 6.277

Review 10.  Utilization of zebrafish for intravital study of eukaryotic pathogen-host interactions.

Authors:  Remi L Gratacap; Robert T Wheeler
Journal:  Dev Comp Immunol       Date:  2014-02-01       Impact factor: 3.636
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