Literature DB >> 23917263

Effect of cross sectional geometry on PDMS micro peristaltic pump performance: comparison of SU-8 replica molding vs. micro injection molding.

Neil J Graf1, Michael T Bowser.   

Abstract

Two different fabrication methods were employed to fabricate micropumps with different cross-sectional channel geometries. The first was to fabricate rectangular cross-sectional microchannel geometries using the well known fabrication method of replica molding (REM). The second, and far less utilized fabrication technique, was to create microchannel molds using an in-house fabricated handheld micro injection molding apparatus. The injection mold apparatus was designed for use with elastomeric room temperature vulcanization (RTV) polymers, as opposed to most other injection molding machines, which are designed for use with thermoplastic polymers. The injection mold's bottom plate was used as a microchannel molding template. The molding template was created by threading a small-diameter wire (150 μm or less) through the injection mold's bottom plate, with subsequent adhesion and smoothing of a thin piece of aluminum foil over the wire-raised injection mold template. When molded against, the template produced a rounded/Gaussian-shaped PDMS microchannel. The design of the injection mold will be presented, along with a direct comparison for micropump performance metrics such as flow rate, valving characteristics, and maximum backpressures attainable for each of the respective micropump channel geometries.

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Year:  2013        PMID: 23917263      PMCID: PMC3795414          DOI: 10.1039/c3an00671a

Source DB:  PubMed          Journal:  Analyst        ISSN: 0003-2654            Impact factor:   4.616


  41 in total

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2.  Prototyping of microfluidic devices in poly(dimethylsiloxane) using solid-object printing.

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Review 4.  Polymer microfabrication methods for microfluidic analytical applications.

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5.  Effect of exposure dose on the replication fidelity and profile of very high aspect ratio microchannels in SU-8.

Authors:  Jun Zhang; Mary B Chan-Park; Samuel R Conner
Journal:  Lab Chip       Date:  2004-11-01       Impact factor: 6.799

6.  Characterization of SU-8 for electrokinetic microfluidic applications.

Authors:  Tiina Sikanen; Santeri Tuomikoski; Raimo A Ketola; Risto Kostiainen; Sami Franssila; Tapio Kotiaho
Journal:  Lab Chip       Date:  2005-07-01       Impact factor: 6.799

7.  Hydrodynamic dispersion in shallow microchannels: the effect of cross-sectional shape.

Authors:  Armand Ajdari; Nathalie Bontoux; Howard A Stone
Journal:  Anal Chem       Date:  2006-01-15       Impact factor: 6.986

8.  Rapid fabrication of poly(dimethylsiloxane)-based microchip capillary electrophoresis devices using CO2 laser ablation.

Authors:  Barbara A Fogarty; Kathleen E Heppert; Theodore J Cory; Kalonie R Hulbutta; R Scott Martin; Susan M Lunte
Journal:  Analyst       Date:  2005-04-25       Impact factor: 4.616

9.  CO(2)-laser micromachining and back-end processing for rapid production of PMMA-based microfluidic systems.

Authors:  Henning Klank; Jorg P Kutter; Oliver Geschke
Journal:  Lab Chip       Date:  2002-09-17       Impact factor: 6.799

Review 10.  Poly(dimethylsiloxane) as a material for fabricating microfluidic devices.

Authors:  J Cooper McDonald; George M Whitesides
Journal:  Acc Chem Res       Date:  2002-07       Impact factor: 22.384

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  2 in total

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2.  Microfluidic System Based High Throughput Drug Screening System for Curcumin/TRAIL Combinational Chemotherapy in Human Prostate Cancer PC3 Cells.

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  2 in total

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