Literature DB >> 23912310

The effects of advanced paternal age on fertility.

Jason R Kovac, Josephine Addai, Ryan P Smith, Robert M Coward, Dolores J Lamb, Larry I Lipshultz.   

Abstract

Modern societal pressures and expectations over the past several decades have resulted in the tendency for couples to delay conception. While women experience a notable decrease in oocyte production in their late thirties, the effect of age on spermatogenesis is less well described. While there are no known limits to the age at which men can father children, the effects of advanced paternal age are incompletely understood. This review summarizes the current state of knowledge regarding advanced paternal age and its implications on semen quality, reproductive success and offspring health. This review will serve as a guide to physicians in counseling men about the decision to delay paternity and the risks involved with conception later in life.

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Year:  2013        PMID: 23912310      PMCID: PMC3854059          DOI: 10.1038/aja.2013.92

Source DB:  PubMed          Journal:  Asian J Androl        ISSN: 1008-682X            Impact factor:   3.285


  89 in total

1.  Paternal age and assisted reproductive technology outcome in ovum recipients.

Authors:  Martha Luna; Elissa Finkler; Jason Barritt; Natan Bar-Chama; Benjamin Sandler; Alan B Copperman; Lawrence Grunfeld
Journal:  Fertil Steril       Date:  2009-06-21       Impact factor: 7.329

2.  Semen quality and sex hormone pattern of 29 middle aged men.

Authors:  Z T Homonnai; N Fainman; M P David; G F Paz
Journal:  Andrologia       Date:  1982 Mar-Apr       Impact factor: 2.775

Review 3.  Delayed childbearing: effects on fertility and the outcome of pregnancy.

Authors:  Juan Balasch; Eduard Gratacós
Journal:  Curr Opin Obstet Gynecol       Date:  2012-06       Impact factor: 1.927

4.  Increasing paternal age is associated with delayed conception in a large population of fertile couples: evidence for declining fecundity in older men. The ALSPAC Study Team (Avon Longitudinal Study of Pregnancy and Childhood).

Authors:  W C Ford; K North; H Taylor; A Farrow; M G Hull; J Golding
Journal:  Hum Reprod       Date:  2000-08       Impact factor: 6.918

Review 5.  Down syndrome: prenatal risk assessment and diagnosis.

Authors:  D S Newberger
Journal:  Am Fam Physician       Date:  2000-08-15       Impact factor: 3.292

6.  Parental age and risk of childhood cancers: a population-based cohort study from Sweden.

Authors:  Benjamin H Yip; Yudi Pawitan; Kamila Czene
Journal:  Int J Epidemiol       Date:  2006-09-28       Impact factor: 7.196

7.  Mutations in fibroblast growth-factor receptor 3 in sporadic cases of achondroplasia occur exclusively on the paternally derived chromosome.

Authors:  D J Wilkin; J K Szabo; R Cameron; S Henderson; G A Bellus; M L Mack; I Kaitila; J Loughlin; A Munnich; B Sykes; J Bonaventure; C A Francomano
Journal:  Am J Hum Genet       Date:  1998-09       Impact factor: 11.025

8.  Paternal age affects fertility and progeny outcome in the Brown Norway rat.

Authors:  V Serre; B Robaire
Journal:  Fertil Steril       Date:  1998-10       Impact factor: 7.329

9.  Effects of age on DNA double-strand breaks and apoptosis in human sperm.

Authors:  Narendra P Singh; Charles H Muller; Richard E Berger
Journal:  Fertil Steril       Date:  2003-12       Impact factor: 7.329

10.  Paternal age and adverse birth outcomes: teenager or 40+, who is at risk?

Authors:  Xi-Kuan Chen; Shi Wu Wen; Daniel Krewski; Nathalie Fleming; Qiuying Yang; Mark C Walker
Journal:  Hum Reprod       Date:  2008-02-06       Impact factor: 6.918

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  31 in total

1.  Is semen analysis necessary prior to the commencement of testosterone supplementation therapy in men of reproductive age?

Authors:  Michael Pan; Ranjith Ramasamy; Jason R Kovac
Journal:  Can Urol Assoc J       Date:  2014-11       Impact factor: 1.862

Review 2.  Oxidative stress and male infertility.

Authors:  Shilpa Bisht; Muneeb Faiq; Madhuri Tolahunase; Rima Dada
Journal:  Nat Rev Urol       Date:  2017-05-16       Impact factor: 14.432

3.  Advanced Parental Age Impaired Fear Conditioning and Hippocampal LTD in Adult Female Rat Offspring.

Authors:  Lilu Luo; Tingting Sun; Xin Guan; Yiling Ni; Liqiang Yang; Quan Zhao; Xiangyang Kong; Yanmei Chen; Jichuan Zhang
Journal:  Neurochem Res       Date:  2017-05-23       Impact factor: 3.996

4.  Trajectories and phenotypes with estrogen exposures across the lifespan: What does Goldilocks have to do with it?

Authors:  Stephanie V Koebele; Heather A Bimonte-Nelson
Journal:  Horm Behav       Date:  2015-06-27       Impact factor: 3.587

5.  Short-acting testosterone appears to have lesser effect on male reproductive potential compared to long-acting testosterone in mice.

Authors:  Kevin Y Chu; Shathiyah Kulandavelu; Thomas A Masterson; Emad Ibrahim; Himanshu Arora; Ranjith Ramasamy
Journal:  F S Sci       Date:  2020-04-14

Review 6.  Animal models of male reproductive ageing to study testosterone production and spermatogenesis.

Authors:  David F Carrageta; Bárbara Guerra-Carvalho; Maria Angélica Spadella; Marc Yeste; Pedro F Oliveira; Marco G Alves
Journal:  Rev Endocr Metab Disord       Date:  2022-05-23       Impact factor: 6.514

7.  Male Rat Germ Cells Display Age-Dependent and Cell-Specific Susceptibility in Response to Oxidative Stress Challenges.

Authors:  Johanna Selvaratnam; Catriona Paul; Bernard Robaire
Journal:  Biol Reprod       Date:  2015-07-29       Impact factor: 4.285

Review 8.  [Social freezing - the male perspective].

Authors:  J Gromoll; F Tüttelmann; S Kliesch
Journal:  Urologe A       Date:  2016-01       Impact factor: 0.639

9.  Influence of age on sperm characteristics evaluated by light and electron microscopies.

Authors:  Giulia Collodel; Fabio Ferretti; Maurizio Masini; Giacomo Gualtieri; Elena Moretti
Journal:  Sci Rep       Date:  2021-03-02       Impact factor: 4.379

10.  Infertile men older than 40 years are at higher risk of sperm DNA damage.

Authors:  Saad Alshahrani; Ashok Agarwal; Mourad Assidi; Adel M Abuzenadah; Damayanthi Durairajanayagam; Ahmet Ayaz; Rakesh Sharma; Edmund Sabanegh
Journal:  Reprod Biol Endocrinol       Date:  2014-11-20       Impact factor: 5.211

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