| Literature DB >> 23911316 |
Ben D MacArthur1, Ihor R Lemischka.
Abstract
Recent reports using single-cell profiling have indicated a remarkably dynamic view of pluripotent stem cell identity. Here, we argue that the pluripotent state is not well defined at the single-cell level but rather is a statistical property of stem cell populations, amenable to analysis using the tools of statistical mechanics and information theory.Mesh:
Year: 2013 PMID: 23911316 DOI: 10.1016/j.cell.2013.07.024
Source DB: PubMed Journal: Cell ISSN: 0092-8674 Impact factor: 41.582