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Literature DB >> 24679530

Rethinking differentiation: stem cells, regeneration, and plasticity.

Alejandro Sánchez Alvarado¹, Shinya Yamanaka².

Abstract

Cell differentiation is an essential process for the development, growth, reproduction, and longevity of all multicellular organisms, and its regulation has been the focus of intense investigation for the past four decades. The study of natural and induced stem cells has ushered an age of re-examination of what it means to be a stem or a differentiated cell. Past and recent discoveries in plants and animals, as well as novel experimental manipulations, are beginning to erode many of these established concepts and are forcing a re-evaluation of the experimental systems and paradigms presently being used to explore these and other biological process.

Entities: Chemical Disease Gene Species

Mesh：

Year: 2014 PMID： 24679530 PMCID： PMC4074550 DOI： 10.1016/j.cell.2014.02.041

Source DB: PubMed Journal: Cell ISSN： 0092-8674 Impact factor: 41.582

84 in total

Review 1. Transcriptional networks and signaling pathways that govern vertebrate intestinal development.

Authors: Joan K Heath
Journal: Curr Top Dev Biol Date: 2010 Impact factor: 4.897

Review 2. Wnt, stem cells and cancer in the intestine.

Authors: Daniel Pinto; Hans Clevers
Journal: Biol Cell Date: 2005-03 Impact factor: 4.458

3. Generation of rat and human induced pluripotent stem cells by combining genetic reprogramming and chemical inhibitors.

Authors: Wenlin Li; Wei Wei; Saiyong Zhu; Jinliang Zhu; Yan Shi; Tongxiang Lin; Ergeng Hao; Alberto Hayek; Hongkui Deng; Sheng Ding
Journal: Cell Stem Cell Date: 2008-12-18 Impact factor: 24.633

Rethinking differentiation: stem cells, regeneration, and plasticity.

Review 1. Transcriptional networks and signaling pathways that govern vertebrate intestinal development.

Review 2. Wnt, stem cells and cancer in the intestine.

3. Generation of rat and human induced pluripotent stem cells by combining genetic reprogramming and chemical inhibitors.

Review 4. Control mechanisms in cell-type conversion in newt lens regeneration.

Review 5. Paneth cells: maestros of the small intestinal crypts.

6. Cellular analysis on localization of lens forming potency in the newt iris epithelium.

7. Telomerase maintained in self-renewing tissues during serial regeneration of the urochordate Botryllus schlosseri.

8. Reprogramming of human somatic cells to pluripotency with defined factors.

9. Identification of stem cells in small intestine and colon by marker gene Lgr5.

10. Striving for normality: whole body regeneration through a series of abnormal generations.

Review 1. The Role of the Microenvironment in Controlling the Fate of Bioprinted Stem Cells.

Review 2. Rejuvenating Strategies for Stem Cell-Based Therapies in Aging.

Review 3. In vivo reprogramming for tissue repair.

4. A phylum-wide survey reveals multiple independent gains of head regeneration in Nemertea.

Review 5. Animal regeneration: ancestral character or evolutionary novelty?

Review 6. TGF-β Family Signaling in Epithelial Differentiation and Epithelial-Mesenchymal Transition.

Review 7. Adult Hippocampal Neurogenesis, Fear Generalization, and Stress.

Review 8. Histone variants and cellular plasticity.

9. Bipotential adult liver progenitors are derived from chronically injured mature hepatocytes.

10. GAMDB: a web resource to connect microRNAs with autophagy in gerontology.