Literature DB >> 23908185

Quantitative OCT-based longitudinal evaluation of intracorneal ring segment implantation in keratoconus.

Pablo Pérez-Merino1, Sergio Ortiz, Nicolas Alejandre, Ignacio Jiménez-Alfaro, Susana Marcos.   

Abstract

PURPOSE: To characterize the geometrical properties of keratoconic corneas upon intracorneal ring segments (ICRS) implantation, using custom-developed optical coherence tomography (OCT).
METHODS: Ten keratoconic corneas were measured pre- and post-ICRS surgery (7, 30, and 90 days). Corneal topographic and pachymetric maps were obtained from three-dimensional (3D) images acquired with OCT, provided with custom algorithms for image analysis, distortion correction, and quantification. The 3D positioning of the ICRS was also estimated longitudinally, relative to the pupil center and iris plane.
RESULTS: Preoperatively, the average corneal radii of curvature were 7.02 ± 0.54 mm (anterior) and 5.40 ± 0.77 mm (posterior), and the minimum corneal thickness was 384 ± 60 μm. At 90 days, the average corneal radii of curvature were 7.26 ± 0.53 mm (anterior) and 5.44 ± 0.71 mm (posterior), and the minimum corneal thickness was 396 ± 46 μm. ICRS implantation produced a significant decrease of corneal power (by 1.71 ± 1.83 diopters [D] at 90 days). Corneal irregularities (defined by high order Zernike terms of the corneal elevation maps) and the corneal thickness distribution decreased in some patients and increased in others. The 3D ICRS depth matched the planned ICRS depth well (within 23.93 ± 23.49 μm). On average, ICRS showed an overall tilt of -6.8 ± 2.6° (temporal) and -2.1 ± 0.8° (superior) at 7 days.
CONCLUSIONS: Spectral OCT (sOCT) provided with distortion correction and analysis tools, is an excellent instrument for evaluating the changes produced by ICRS in keratoconic corneas, and for analyzing the 3D ICRS position during the follow up. ICRS produced flattening on the anterior corneal surface, although the benefit for corneal surface regularization varied across patients.

Entities:  

Keywords:  corneal topography; intracorneal ring segments (ICRS); keratoconus; optical coherence tomography (OCT)

Mesh:

Year:  2013        PMID: 23908185     DOI: 10.1167/iovs.13-12401

Source DB:  PubMed          Journal:  Invest Ophthalmol Vis Sci        ISSN: 0146-0404            Impact factor:   4.799


  6 in total

1.  OCT-based crystalline lens topography in accommodating eyes.

Authors:  Pablo Pérez-Merino; Miriam Velasco-Ocana; Eduardo Martinez-Enriquez; Susana Marcos
Journal:  Biomed Opt Express       Date:  2015-11-24       Impact factor: 3.732

2.  Tissue reaction after intrastromal corneal ring implantation in an experimental animal model.

Authors:  Lucía Ibares-Frías; Patricia Gallego; Roberto Cantalapiedra-Rodríguez; María Cruz Valsero; Santiago Mar; Jesús Merayo-Lloves; María Carmen Martínez-García
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2015-03-07       Impact factor: 3.117

3.  Keraring Intrastromal Segment Depth Measured by Spectral-Domain Optical Coherence Tomography in Eyes with Keratoconus.

Authors:  Ugo de Sanctis; Carlo Lavia; Marco Nassisi; Savino D'Amelio
Journal:  J Ophthalmol       Date:  2017-02-02       Impact factor: 1.909

Review 4.  Optical coherence tomography for ocular surface and corneal diseases: a review.

Authors:  Nandini Venkateswaran; Anat Galor; Jianhua Wang; Carol L Karp
Journal:  Eye Vis (Lond)       Date:  2018-06-12

5.  Influence of pterygium size on corneal higher-order aberration evaluated using anterior-segment optical coherence tomography.

Authors:  Keiichiro Minami; Tadatoshi Tokunaga; Keiichiro Okamoto; Kazunori Miyata; Tetsuro Oshika
Journal:  BMC Ophthalmol       Date:  2018-07-09       Impact factor: 2.209

6.  Optical Evaluation of Intracorneal Ring Segment Surgery in Keratoconus.

Authors:  Nicolas Alejandre; Pablo Pérez-Merino; Gonzalo Velarde; Ignacio Jiménez-Alfaro; Susana Marcos
Journal:  Transl Vis Sci Technol       Date:  2022-03-02       Impact factor: 3.048

  6 in total

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