BACKGROUND: Data on implant allergies are incomplete; therefore, we compared the data on allergy history, patch test (PT) and lymphocyte transformation test (LTT) results in a patient series from the Munich implant allergy outpatient department with symptom-free arthroplasty patients. PATIENTS AND METHODS: In this study 200 arthroplasty patients with complaints involving the prosthesis (130 female, 187 knee and 13 hip prostheses) and in parallel 100 symptom-free patients (75 female, 47 knee and 53 hip prostheses) were investigated. A questionnaire-aided history including implant type, cementing, intolerance of dental materials, atopy, cutaneous metal intolerance (CMI) and PT, including a standard series with Ni, Co, Cr, seven bone cement components, including gentamicin and benzoyl peroxide and LTT for Ni, Co and Cr. RESULTS: In the knee arthroplasty patients with complaints 9.1% showed dental material intolerance, 23.5% atopy, 25.7% CMI, 18.2% metal allergies, 7.4% gentamicin allergy and 27.8% positive metal LTT (mostly to Ni). In symptom-free patients 0% showed dental material intolerance, 19.1% atopy, 12.8% CMI, 12.8% metal allergy, 0% gentamicin allergy and 17% positive metal LTT. CONCLUSIONS: Characteristics of the patients with complaints were increased intolerance of dental materials, higher rates of atopy, CMI, metal and gentamicin allergy and LTT reactivity.
BACKGROUND: Data on implant allergies are incomplete; therefore, we compared the data on allergy history, patch test (PT) and lymphocyte transformation test (LTT) results in a patient series from the Munich implant allergyoutpatient department with symptom-free arthroplasty patients. PATIENTS AND METHODS: In this study 200 arthroplasty patients with complaints involving the prosthesis (130 female, 187 knee and 13 hip prostheses) and in parallel 100 symptom-free patients (75 female, 47 knee and 53 hip prostheses) were investigated. A questionnaire-aided history including implant type, cementing, intolerance of dental materials, atopy, cutaneous metal intolerance (CMI) and PT, including a standard series with Ni, Co, Cr, seven bone cement components, including gentamicin and benzoyl peroxide and LTT for Ni, Co and Cr. RESULTS: In the knee arthroplasty patients with complaints 9.1% showed dental material intolerance, 23.5% atopy, 25.7% CMI, 18.2% metalallergies, 7.4% gentamicinallergy and 27.8% positive metal LTT (mostly to Ni). In symptom-free patients 0% showed dental material intolerance, 19.1% atopy, 12.8% CMI, 12.8% metalallergy, 0% gentamicinallergy and 17% positive metal LTT. CONCLUSIONS: Characteristics of the patients with complaints were increased intolerance of dental materials, higher rates of atopy, CMI, metal and gentamicinallergy and LTT reactivity.
Authors: Axel Schnuch; Werner Aberer; Monika Agathos; Detlef Becker; Jochen Brasch; Peter Elsner; Peter J Frosch; Thomas Fuchs; Johannes Geier; Uwe Hillen; Harald Löffler; Vera Mahler; Gerhard Richter; Christiane Szliska Journal: J Dtsch Dermatol Ges Date: 2008-09 Impact factor: 5.584
Authors: F Mazoochian; F Schmidutz; J Kiefl; A Fottner; B Michalke; R Schierl; P Thomas; V Jansson Journal: Acta Chir Belg Date: 2013 Mar-Apr Impact factor: 1.090
Authors: Young-Min Kwon; Peter Thomas; Burkhard Summer; Hemant Pandit; Adrian Taylor; David Beard; David W Murray; Harinderjit S Gill Journal: J Orthop Res Date: 2010-04 Impact factor: 3.494
Authors: Peter Thomas; Christine von der Helm; Christoph Schopf; Farhad Mazoochian; Lars Frommelt; Hans Gollwitzer; Josef Schneider; Michael Flaig; Veit Krenn; Benjamin Thomas; Burkhard Summer Journal: Biomed Res Int Date: 2015-03-19 Impact factor: 3.411
Authors: Klemens Trieb; Andreas Artmann; Michael Krupa; Sasch Senck; Franz Landauer Journal: Medicine (Baltimore) Date: 2022-09-30 Impact factor: 1.817