Literature DB >> 23907189

A blooming resolvase at chromosomal fragile sites.

Achille Pellicioli, Marco Muzi-Falconi.   

Abstract

Common fragile sites (CFSs) are chromosomal regions that are prone to form breaks or gaps during mitosis, in particular following replication stress. The mechanisms modulating CFS expression and promoting safe chromatid transmission to daughter cells are not clear. Now CFS expression is shown to reflect the activity of the MUS81-EME1 resolvase complex which cooperates with the dissolving action of the BLM helicase to prevent uncontrolled chromosome breakage and to promote genome integrity.

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Year:  2013        PMID： 23907189     DOI： 10.1038/ncb2812

Source DB:  PubMed          Journal:  Nat Cell Biol        ISSN： 1465-7392            Impact factor:   28.824


  17 in total

1.  ATR regulates fragile site stability.

Authors:  Anne M Casper; Paul Nghiem; Martin F Arlt; Thomas W Glover
Journal:  Cell       Date:  2002-12-13       Impact factor: 41.582

Review 2.  The molecular basis of common and rare fragile sites.

Authors:  Michal Schwartz; Eitan Zlotorynski; Batsheva Kerem
Journal:  Cancer Lett       Date:  2005-10-19       Impact factor: 8.679

3.  To trim or not to trim: progression and control of DSB end resection.

Authors:  Magda Granata; Davide Panigada; Elena Galati; Federico Lazzaro; Achille Pellicioli; Paolo Plevani; Marco Muzi-Falconi
Journal:  Cell Cycle       Date:  2013-05-29       Impact factor: 4.534

4.  53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress.

Authors:  Claudia Lukas; Velibor Savic; Simon Bekker-Jensen; Carsten Doil; Beate Neumann; Ronni Sølvhøj Pedersen; Merete Grøfte; Kok Lung Chan; Ian David Hickson; Jiri Bartek; Jiri Lukas
Journal:  Nat Cell Biol       Date:  2011-02-13       Impact factor: 28.824

5.  Coordination of structure-specific nucleases by human SLX4/BTBD12 is required for DNA repair.

Authors:  Ivan M Muñoz; Karolina Hain; Anne-Cécile Déclais; Mary Gardiner; Geraldine W Toh; Luis Sanchez-Pulido; Johannes M Heuckmann; Rachel Toth; Thomas Macartney; Berina Eppink; Roland Kanaar; Chris P Ponting; David M J Lilley; John Rouse
Journal:  Mol Cell       Date:  2009-07-10       Impact factor: 17.970

6.  BLM is required for faithful chromosome segregation and its localization defines a class of ultrafine anaphase bridges.

Authors:  Kok-Lung Chan; Phillip S North; Ian D Hickson
Journal:  EMBO J       Date:  2007-06-28       Impact factor: 11.598

7.  ERCC1 and MUS81-EME1 promote sister chromatid separation by processing late replication intermediates at common fragile sites during mitosis.

Authors:  Valeria Naim; Therese Wilhelm; Michelle Debatisse; Filippo Rosselli
Journal:  Nat Cell Biol       Date:  2013-06-30       Impact factor: 28.824

Review 8.  Chromosome fragile sites.

Authors:  Sandra G Durkin; Thomas W Glover
Journal:  Annu Rev Genet       Date:  2007       Impact factor: 16.830

9.  Replication stress induces 53BP1-containing OPT domains in G1 cells.

Authors:  Jeanine A Harrigan; Rimma Belotserkovskaya; Julia Coates; Daniela S Dimitrova; Sophie E Polo; Charles R Bradshaw; Peter Fraser; Stephen P Jackson
Journal:  J Cell Biol       Date:  2011-03-28       Impact factor: 10.539

10.  Werner syndrome helicase activity is essential in maintaining fragile site stability.

Authors:  Livia Maria Pirzio; Pietro Pichierri; Margherita Bignami; Annapaola Franchitto
Journal:  J Cell Biol       Date:  2008-01-21       Impact factor: 10.539
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  6 in total

Review 1.  Human RecQ helicases in DNA repair, recombination, and replication.

Authors:  Deborah L Croteau; Venkateswarlu Popuri; Patricia L Opresko; Vilhelm A Bohr
Journal:  Annu Rev Biochem       Date:  2014-03-03       Impact factor: 23.643

2.  FANCD2 Facilitates Replication through Common Fragile Sites.

Authors:  Advaitha Madireddy; Settapong T Kosiyatrakul; Rebecca A Boisvert; Emilia Herrera-Moyano; María L García-Rubio; Jeannine Gerhardt; Elizabeth A Vuono; Nichole Owen; Zi Yan; Susan Olson; Andrés Aguilera; Niall G Howlett; Carl L Schildkraut
Journal:  Mol Cell       Date:  2016-10-20       Impact factor: 17.970

3.  DNA secondary structure at chromosomal fragile sites in human disease.

Authors:  Ryan G Thys; Christine E Lehman; Levi C T Pierce; Yuh-Hwa Wang
Journal:  Curr Genomics       Date:  2015-02       Impact factor: 2.236

Review 4.  Are common fragile sites merely structural domains or highly organized "functional" units susceptible to oncogenic stress?

Authors:  Alexandros G Georgakilas; Petros Tsantoulis; Athanassios Kotsinas; Ioannis Michalopoulos; Paul Townsend; Vassilis G Gorgoulis
Journal:  Cell Mol Life Sci       Date:  2014-09-20       Impact factor: 9.261

5.  Saccharomyces cerevisiae Mus81-Mms4 prevents accelerated senescence in telomerase-deficient cells.

Authors:  Erin K Schwartz; Shih-Hsun Hung; Damon Meyer; Aurèle Piazza; Kevin Yan; Becky Xu Hua Fu; Wolf-Dietrich Heyer
Journal:  PLoS Genet       Date:  2020-05-29       Impact factor: 5.917

6.  Topoisomerase II contributes to DNA secondary structure-mediated double-stranded breaks.

Authors:  Karol Szlachta; Arkadi Manukyan; Heather M Raimer; Sandeep Singh; Anita Salamon; Wenying Guo; Kirill S Lobachev; Yuh-Hwa Wang
Journal:  Nucleic Acids Res       Date:  2020-07-09       Impact factor: 19.160
  6 in total

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