Literature DB >> 23884238

Frequency of debridements and time to heal: a retrospective cohort study of 312 744 wounds.

James R Wilcox1, Marissa J Carter, Scott Covington.   

Abstract

IMPORTANCE: Chronic wounds usually get trapped in the inflammatory stage of wound healing; however, aggressive debridement transforms chronic wounds to acute wounds and therefore complete healing.
OBJECTIVE: To investigate healing outcomes and debridement frequency in a large wound data set.
DESIGN: Retrospective cohort study.
SETTING: Data collected from 525 wound care centers from June 1, 2008, through June 31, 2012, using a web-based clinical management system. PATIENTS: Referred sample of 154 644 patients with 312 744 wounds of all causes (of an initial data set of 364 534 wounds) participated. A total of 47.1% were male. Median age was 69 years (age range, 19-112 years), with 59.2% having one wound. Eligibility criteria included age older than 18 years, receiving at least 1 debridement, and having been discharged from the system. Advanced therapeutic treatment was ineligible. Because of incomplete, questionable, or ineligible data, 57 190 wounds were not included. Most wounds were diabetic foot ulcers (19.0%), venous leg ulcers (26.1%), and pressure ulcers (16.2%). INTERVENTION: Debridement (removal of necrotic tissue and foreign bodies from the wound) at different frequencies. MAIN OUTCOME AND MEASURE: Wound healing (completely epithelialized with dimensions at 0 × 0 × 0 cm).
RESULTS: A total of 70.8% of wounds healed. The median number of debridements was 2 (range, 1-138). Frequent debridement healed more wounds in a shorter time (P <  .001). In regression analysis, significant variables included male sex, physician category, wound type, increased patient age, and increased wound age, area, and depth. The odds ratio varied considerably for each variable. CONCLUSIONS AND RELEVANCE: The more frequent the debridements, the better the healing outcome. Although limited by retrospective data, this study's strength was the analysis of the largest wound data set to date.

Entities:  

Mesh:

Year:  2013        PMID: 23884238     DOI: 10.1001/jamadermatol.2013.4960

Source DB:  PubMed          Journal:  JAMA Dermatol        ISSN: 2168-6068            Impact factor:   10.282


  27 in total

1.  Innovative pain management solutions in animals may provide improved wound pain reduction during debridement in humans: An opinion informed by veterinary literature.

Authors:  Christopher D Roberts; Peter A Windsor
Journal:  Int Wound J       Date:  2019-04-01       Impact factor: 3.315

2.  Prevalence and healthcare costs associated with the management of diabetic foot ulcer in patients attending Ahmadu Bello University Teaching Hospital, Nigeria.

Authors:  Umar Mukhtar Danmusa; Iorliam Terhile; Idris Abdullahi Nasir; Auwal Alkasim Ahmad; Habiba Yahaya Muhammad
Journal:  Int J Health Sci (Qassim)       Date:  2016-04

3.  What is the optimal treatment time for larval therapy? A study on incubation time and tissue debridement by bagged maggots of the greenbottle fly, Lucilia sericata.

Authors:  Michael R Wilson; Yamni Nigam; John Knight; David I Pritchard
Journal:  Int Wound J       Date:  2018-10-31       Impact factor: 3.315

4.  [Diabetic foot syndrome].

Authors:  K Dresing
Journal:  Oper Orthop Traumatol       Date:  2016-10       Impact factor: 1.154

5.  Study on the Effect of the Five-in-One Comprehensive Limb Salvage Technologies of Treating Severe Diabetic Foot.

Authors:  Yiling Liu; Yan Shi; Junyou Zhu; XiaoDong Chen; RongHua Yang; Bin Shu; Ziheng Zhou; Jian Liu; Ri-Qiang Wu; Julin Xie
Journal:  Adv Wound Care (New Rochelle)       Date:  2019-11-19       Impact factor: 4.730

Review 6.  Literature review on the management of diabetic foot ulcer.

Authors:  Leila Yazdanpanah; Morteza Nasiri; Sara Adarvishi
Journal:  World J Diabetes       Date:  2015-02-15

7.  Diabetic foot infection: A critical complication.

Authors:  Jennifer J Hurlow; Gavin J Humphreys; Frank L Bowling; Andrew J McBain
Journal:  Int Wound J       Date:  2018-05-28       Impact factor: 3.315

8.  Rapid detection of biofilm by wound blotting following sharp debridement of chronic pressure ulcers predicts wound healing: A preliminary study.

Authors:  Gojiro Nakagami; Gregory Schultz; Aya Kitamura; Takeo Minematsu; Kaname Akamata; Hiraku Suga; Masakazu Kurita; Chieko Hayashi; Hiromi Sanada
Journal:  Int Wound J       Date:  2019-11-04       Impact factor: 3.315

Review 9.  Metagenomics to Identify Pathogens in Diabetic Foot Ulcers and the Potential Impact for Clinical Care.

Authors:  Brian M Schmidt; John Erb-Downward; Piyush Ranjan; Robert Dickson
Journal:  Curr Diab Rep       Date:  2021-06-21       Impact factor: 4.810

10.  Analgesic efficacy of equimolar 50% nitrous oxide/oxygen gas premix (Kalinox®) as compared with a 5% eutectic mixture of lidocaine/prilocaine (EMLA®) in chronic leg ulcer debridement.

Authors:  Juerg Traber; Ulrike Held; Maria Signer; Tobias Huebner; Stefan Arndt; Thomas A Neff
Journal:  Int Wound J       Date:  2016-08-08       Impact factor: 3.315

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