| Literature DB >> 23859712 |
Mary S Noé1, Renatus W Sinkeldam, Yitzhak Tor.
Abstract
5-(Thien-2-yl)-2'-deoxyuridine, an isomorphic fluorescent nucleoside analogue, was incorporated into multiple positions within single stranded oligodeoxynucleotides. With minimal impact on duplex stability and overall structure, oligonucleotides containing three identical isomorphic fluorescent nucleosides in alternating or neighboring positions display enhanced, sequence-dependent on-signals for either duplex formation or dissociation.Entities:
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Year: 2013 PMID: 23859712 PMCID: PMC3799853 DOI: 10.1021/jo4008964
Source DB: PubMed Journal: J Org Chem ISSN: 0022-3263 Impact factor: 4.354