Literature DB >> 23859712

Oligodeoxynucleotides containing multiple thiophene-modified isomorphic fluorescent nucleosides.

Mary S Noé1, Renatus W Sinkeldam, Yitzhak Tor.   

Abstract

5-(Thien-2-yl)-2'-deoxyuridine, an isomorphic fluorescent nucleoside analogue, was incorporated into multiple positions within single stranded oligodeoxynucleotides. With minimal impact on duplex stability and overall structure, oligonucleotides containing three identical isomorphic fluorescent nucleosides in alternating or neighboring positions display enhanced, sequence-dependent on-signals for either duplex formation or dissociation.

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Year:  2013        PMID: 23859712      PMCID: PMC3799853          DOI: 10.1021/jo4008964

Source DB:  PubMed          Journal:  J Org Chem        ISSN: 0022-3263            Impact factor:   4.354


  22 in total

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  9 in total

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Authors:  Sazzad H Suzol; A Hasan Howlader; Zhiwei Wen; Yaou Ren; Eduardo E Laverde; Carol Garcia; Yuan Liu; Stanislaw F Wnuk
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4.  The linkers in fluorene-labeled 2'-deoxyuridines affect fluorescence discriminating phenomena upon duplex formation.

Authors:  So Young Lee; Seung Woo Hong; Hyeonuk Yeo; Gil Tae Hwang
Journal:  RSC Adv       Date:  2020-05-19       Impact factor: 3.361

5.  Probing G-quadruplex topologies and recognition concurrently in real time and 3D using a dual-app nucleoside probe.

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6.  Palladium-catalyzed direct arylation of 5-halouracils and 5-halouracil nucleosides with arenes and heteroarenes promoted by TBAF.

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7.  Probing Human Telomeric DNA and RNA Topology and Ligand Binding in a Cellular Model by Using Responsive Fluorescent Nucleoside Probes.

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8.  A Lucifer-Based Environment-Sensitive Fluorescent PNA Probe for Imaging Poly(A) RNAs.

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Review 9.  NAD Analogs in Aid of Chemical Biology and Medicinal Chemistry.

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  9 in total

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