Literature DB >> 23859218

Synthesis of 6-Se-guanosine RNAs for structural study.

Jozef Salon1, Jianhua Gan, Rob Abdur, Hehua Liu, Zhen Huang.   

Abstract

6-Se-guanosine phosphoramidite and RNAs have been synthesized by selenium substitution of the 6-oxygen atom, and it is revealed that the Se-derivatization is relatively stable and that bulge and wobble structures can better accommodate a large Se atom than a duplex. This Se-modification is useful in the structural study of RNAs and their protein complexes.

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Year:  2013        PMID： 23859218      PMCID： PMC3763942          DOI： 10.1021/ol401698n

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  17 in total

1.  Crystal structure of a model branchpoint-U2 snRNA duplex containing bulged adenosines.

Authors:  J A Berglund; M Rosbash; S C Schultz
Journal:  RNA       Date:  2001-05       Impact factor: 4.942

2.  The crystal structure of human Argonaute2.

Authors:  Nicole T Schirle; Ian J MacRae
Journal:  Science       Date:  2012-04-26       Impact factor: 47.728

Review 3.  Nucleic acid X-ray crystallography via direct selenium derivatization.

Authors:  Lina Lin; Jia Sheng; Zhen Huang
Journal:  Chem Soc Rev       Date:  2011-06-13       Impact factor: 54.564

4.  Structures from anomalous diffraction of native biological macromolecules.

Authors:  Qun Liu; Tassadite Dahmane; Zhen Zhang; Zahra Assur; Julia Brasch; Lawrence Shapiro; Filippo Mancia; Wayne A Hendrickson
Journal:  Science       Date:  2012-05-25       Impact factor: 47.728

5.  Synthesis of selenium-derivatized nucleosides and oligonucleotides for X-ray crystallography.

Authors:  N Carrasco; D Ginsburg; Q Du; Z Huang
Journal:  Nucleosides Nucleotides Nucleic Acids       Date:  2001-09       Impact factor: 1.381

6.  Hydrogen bond formation between the naturally modified nucleobase and phosphate backbone.

Authors:  Jia Sheng; Wen Zhang; Abdalla E A Hassan; Jianhua Gan; Alexei S Soares; Song Geng; Yi Ren; Zhen Huang
Journal:  Nucleic Acids Res       Date:  2012-05-28       Impact factor: 16.971

7.  Novel RNA base pair with higher specificity using single selenium atom.

Authors:  Huiyan Sun; Jia Sheng; Abdalla E A Hassan; Sibo Jiang; Jianhua Gan; Zhen Huang
Journal:  Nucleic Acids Res       Date:  2012-02-09       Impact factor: 16.971

8.  Selenium derivatization of nucleic acids for crystallography.

Authors:  Jiansheng Jiang; Jia Sheng; Nicolas Carrasco; Zhen Huang
Journal:  Nucleic Acids Res       Date:  2006-12-14       Impact factor: 16.971

9.  Structure of yeast Argonaute with guide RNA.

Authors:  Kotaro Nakanishi; David E Weinberg; David P Bartel; Dinshaw J Patel
Journal:  Nature       Date:  2012-06-20       Impact factor: 49.962

10.  Derivatization of DNAs with selenium at 6-position of guanine for function and crystal structure studies.

Authors:  Jozef Salon; Jiansheng Jiang; Jia Sheng; Oksana O Gerlits; Zhen Huang
Journal:  Nucleic Acids Res       Date:  2008-11-05       Impact factor: 16.971
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  3 in total

1.  Synthesis and optical behaviors of 6-seleno-deoxyguanosine.

Authors:  Kaur Manindar; Huang Zhen
Journal:  Sci China Chem       Date:  2014-02-01       Impact factor: 9.445

2.  Excited-State Properties and Relaxation Pathways of Selenium-Substituted Guanine Nucleobase in Aqueous Solution and DNA Duplex.

Authors:  Ye-Guang Fang; Danillo Valverde; Sebastian Mai; Sylvio Canuto; Antonio Carlos Borin; Ganglong Cui; Leticia González
Journal:  J Phys Chem B       Date:  2021-02-11       Impact factor: 2.991

3.  Ultrafast Intersystem Crossing Dynamics of 6-Selenoguanine in Water.

Authors:  Danillo Valverde; Sebastian Mai; Sylvio Canuto; Antonio Carlos Borin; Leticia González
Journal:  JACS Au       Date:  2022-06-28
  3 in total

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