Literature DB >> 23838500

Clinical efficacy and cost effectiveness of intraoperative cell salvage in pelvic trauma surgery.

S Odak1, A Raza, N Shah, A Clayson.   

Abstract

INTRODUCTION: Pelvic acetabular injuries are associated with significant blood loss. This is compounded by multiple surgical interventions including definitive fracture fixation, which put patients at further risk of postoperative transfusion. We use intraoperative cell salvage routinely as a blood conservation strategy to address this issue. This is a prospective evaluation of the clinical efficacy and cost effectiveness of using intraoperative cell salvage in patients with pelvic acetabular injuries.
METHODS: Data were collected prospectively for all the patients who underwent pelvic acetabular fracture fixation at our institution. A total of 30 patients (25 men, 5 women) with a mean age of 41 years (range: 31-79 years) were assessed over a period of 10 months.
RESULTS: The mean preoperative and postoperative haemoglobin levels were 11.8g/dl and 9.9g/dl respectively. The mean intraoperative blood loss was 1,232.5ml (range: 150-2,693ml). The mean amount of blood salvaged and retransfused through a cell saver was 388ml. Of the 30 patients, 14 (47%) required transfusion after surgery and 26 units of blood were transfused. In terms of cost effectiveness, a total of £2,572 in 30 patients or £86 per patient were saved.
CONCLUSIONS: We found intraoperative cell salvage to be clinically efficacious and cost effective in patients with pelvic acetabular injuries.

Entities:  

Mesh:

Year:  2013        PMID: 23838500      PMCID: PMC4165140          DOI: 10.1308/003588413X13629960045715

Source DB:  PubMed          Journal:  Ann R Coll Surg Engl        ISSN: 0035-8843            Impact factor:   1.891


  21 in total

1.  The immunomodulatory effects of blood transfusion.

Authors:  H G Klein
Journal:  Tumori       Date:  2001 Mar-Apr       Impact factor: 2.098

Review 2.  Risks of blood transfusion.

Authors:  Lawrence T Goodnough
Journal:  Crit Care Med       Date:  2003-12       Impact factor: 7.598

3.  Transfusion-associated hepatitis not due to viral hepatitis type A or B.

Authors:  S M Feinstone; A Z Kapikian; R H Purcell; H J Alter; P V Holland
Journal:  N Engl J Med       Date:  1975-04-10       Impact factor: 91.245

Review 4.  Pelvic ring fractures: should they be fixed?

Authors:  M Tile
Journal:  J Bone Joint Surg Br       Date:  1988-01

5.  Acute intravascular hemolysis secondaryto out-of-group platelet transfusion.

Authors:  L G Larsson; V J Welsh; D J Ladd
Journal:  Transfusion       Date:  2000-08       Impact factor: 3.157

6.  Intraoperative autotransfusion.

Authors:  K Bjerre-Jepsen; P Kristensen; A Horn; K Rydahl
Journal:  Acta Chir Scand       Date:  1982

7.  Allogeneic blood transfusion increases the risk of postoperative bacterial infection: a meta-analysis.

Authors:  Gary E Hill; William H Frawley; Karl E Griffith; John E Forestner; Joseph P Minei
Journal:  J Trauma       Date:  2003-05

8.  Estimating the risks of transfusion-associated acquired immune deficiency syndrome and human immunodeficiency virus infection.

Authors:  T A Peterman; K J Lui; D N Lawrence; J R Allen
Journal:  Transfusion       Date:  1987 Sep-Oct       Impact factor: 3.157

9.  Efficacy of intraoperative blood collection and reinfusion in revision total hip arthroplasty.

Authors:  Jeffrey Zarin; David Grosvenor; David Schurman; Stuart Goodman
Journal:  J Bone Joint Surg Am       Date:  2003-11       Impact factor: 5.284

10.  Pelvic fractures: epidemiology and predictors of associated abdominal injuries and outcomes.

Authors:  Demetrios Demetriades; Marios Karaiskakis; Konstantinos Toutouzas; Kathleen Alo; George Velmahos; Linda Chan
Journal:  J Am Coll Surg       Date:  2002-07       Impact factor: 6.113

View more
  9 in total

1.  [Cost analysis of patient blood management].

Authors:  A G Kleinerüschkamp; K Zacharowski; C Ettwein; M M Müller; C Geisen; C F Weber; P Meybohm
Journal:  Anaesthesist       Date:  2016-05-09       Impact factor: 1.041

2.  The use of intraoperative cell salvage in urologic oncology.

Authors:  Matthew C Ferroni; Andres F Correa; Timothy D Lyon; Benjamin J Davies; Michael C Ost
Journal:  Rev Urol       Date:  2017

3.  Intra-operative cell salvage in pelvic and acetabular fracture surgery: a retrospective comparative study.

Authors:  Abdulla Jawed; Awaiz Ahmed; Mark Rees Williams
Journal:  Int Orthop       Date:  2018-08-15       Impact factor: 3.075

Review 4.  Is there a role for antifibrinolytics in pelvic and acetabular fracture surgery?

Authors:  R P Piggott; M Leonard
Journal:  Ir J Med Sci       Date:  2015-11-11       Impact factor: 1.568

5.  The efficiency and safety of intravenous tranexamic acid administration in open reduction and internal fixation of pelvic and acetabular fractures.

Authors:  Seyit Ali Gümüştaş; Zekeriya Ersin Çelen; Tolga Onay; Mehmet Süleyman Abul; Hüseyin Bilgehan Çevik
Journal:  Eur J Trauma Emerg Surg       Date:  2021-02-27       Impact factor: 3.693

6.  Preoperative anemia and deep vein thrombosis in patients with perioperative bone trauma: a cohort study.

Authors:  Hui Zhang; Linqin Wu; Bo Cheng
Journal:  BMC Musculoskelet Disord       Date:  2022-10-10       Impact factor: 2.562

7.  [Research progress on tranexamic acid in traumatic orthopedic surgery].

Authors:  Shaoyun Zhang; Cong Xiao; Fuxing Pei
Journal:  Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi       Date:  2019-11-15

8.  Intraoperative cell salvage use reduces the rate of perioperative allogenic blood transfusion in patients undergoing periacetabular osteotomy.

Authors:  Michael van der Merwe; Nicholas J Lightfoot; Jacob T Munro; Matthew J Boyle
Journal:  J Hip Preserv Surg       Date:  2019-10-12

9.  Efficacy of Intraoperative Blood Salvage in Cerebral Aneurysm Surgery.

Authors:  Bedjan Behmanesh; Florian Gessler; Elisabeth Adam; Ulrich Strouhal; Sae-Yeon Won; Daniel Dubinski; Volker Seifert; Juergen Konczalla; Christian Senft
Journal:  J Clin Med       Date:  2021-12-07       Impact factor: 4.241

  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.