Literature DB >> 23817666

Bioactive natural products derived from the Central African flora against neglected tropical diseases and HIV.

Denis Zofou1, Fidele Ntie-Kang, Wolfgang Sippl, Simon M N Efange.   

Abstract

This review discusses the medicinal potential of bioactive metabolites isolated from medicinal plants in Central Africa for the treatment of neglected tropical diseases and HIV. A correlation is established between the biological activities of the isolated compounds and the uses of the plants in traditional medicine. Insight is provided on how secondary metabolites from medicinal plants in Central Africa could be exploited for drug discovery.

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Year:  2013        PMID： 23817666     DOI： 10.1039/c3np70030e

Source DB:  PubMed          Journal:  Nat Prod Rep        ISSN： 0265-0568            Impact factor:   13.423


  20 in total

1.  Enhancing malaria control using Lagenaria siceraria and its mediated zinc oxide nanoparticles against the vector Anopheles stephensi and its parasite Plasmodium falciparum.

Authors:  V N Kalpana; Khaloud Mohammed Alarjani; V Devi Rajeswari
Journal:  Sci Rep       Date:  2020-12-09       Impact factor: 4.379

Review 2.  The potential of anti-malarial compounds derived from African medicinal plants, part II: a pharmacological evaluation of non-alkaloids and non-terpenoids.

Authors:  Fidele Ntie-Kang; Pascal Amoa Onguéné; Lydia L Lifongo; Jean Claude Ndom; Wolfgang Sippl; Luc Meva'a Mbaze
Journal:  Malar J       Date:  2014-03-06       Impact factor: 2.979

3.  AfroDb: a select highly potent and diverse natural product library from African medicinal plants.

Authors:  Fidele Ntie-Kang; Denis Zofou; Smith B Babiaka; Rolande Meudom; Michael Scharfe; Lydia L Lifongo; James A Mbah; Luc Meva'a Mbaze; Wolfgang Sippl; Simon M N Efange
Journal:  PLoS One       Date:  2013-10-30       Impact factor: 3.240

Review 4.  The potential of anti-malarial compounds derived from African medicinal plants, part I: a pharmacological evaluation of alkaloids and terpenoids.

Authors:  Pascal Amoa Onguéné; Fidele Ntie-Kang; Lydia Likowo Lifongo; Jean Claude Ndom; Wolfgang Sippl; Luc Meva'a Mbaze
Journal:  Malar J       Date:  2013-12-13       Impact factor: 2.979

5.  In silico drug metabolism and pharmacokinetic profiles of natural products from medicinal plants in the Congo basin.

Authors:  Fidele Ntie-Kang; Lydia L Lifongo; James A Mbah; Luc C Owono Owono; Eugene Megnassan; Luc Meva'a Mbaze; Philip N Judson; Wolfgang Sippl; Simon M N Efange
Journal:  In Silico Pharmacol       Date:  2013-08-08

6.  Virtualizing the p-ANAPL library: a step towards drug discovery from African medicinal plants.

Authors:  Fidele Ntie-Kang; Pascal Amoa Onguéné; Ghislain W Fotso; Kerstin Andrae-Marobela; Merhatibeb Bezabih; Jean Claude Ndom; Bonaventure T Ngadjui; Abiodun O Ogundaini; Berhanu M Abegaz; Luc Mbaze Meva'a
Journal:  PLoS One       Date:  2014-03-05       Impact factor: 3.240

Review 7.  A bioactivity versus ethnobotanical survey of medicinal plants from Nigeria, west Africa.

Authors:  Lydia L Lifongo; Conrad V Simoben; Fidele Ntie-Kang; Smith B Babiaka; Philip N Judson
Journal:  Nat Prod Bioprospect       Date:  2014-03-02

8.  New antimalarial hits from Dacryodes edulis (Burseraceae)--part I: isolation, in vitro activity, in silico "drug-likeness" and pharmacokinetic profiles.

Authors:  Denis Zofou; Esther Laure Tematio; Fidele Ntie-Kang; Mathieu Tene; Moses N Ngemenya; Pierre Tane; Vincent P K Titanji
Journal:  PLoS One       Date:  2013-11-08       Impact factor: 3.240

Review 9.  The Chemistry and Biological Activities of Natural Products from Northern African Plant Families: From Taccaceae to Zygophyllaceae.

Authors:  Fidele Ntie-Kang; Leonel E Njume; Yvette I Malange; Stefan Günther; Wolfgang Sippl; Joseph N Yong
Journal:  Nat Prod Bioprospect       Date:  2016-03-01

10.  Antiplasmodial Ealapasamines A-C,'Mixed' Naphthylisoquinoline Dimers from the Central African Liana Ancistrocladus ealaensis.

Authors:  Dieudonné Tshitenge Tshitenge; Doris Feineis; Virima Mudogo; Marcel Kaiser; Reto Brun; Gerhard Bringmann
Journal:  Sci Rep       Date:  2017-07-18       Impact factor: 4.379
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