Ahmet Kaya1, Turgay Isik2, Yasemin Kaya3, Ozgur Enginyurt4, Zeki Yuksel Gunaydin5, Murat Dogan Iscanli6, Mustafa Kurt2, Ibrahim Halil Tanboga7. 1. Department of Cardiology, Ordu University Medical School, Ordu, Turkey doktorahmetkaya@yahoo.com. 2. Department of Cardiology, Erzurum Education and Research Hospital, Erzurum, Turkey. 3. Department of Internal Medicine, Ordu University Medical School, Ordu, Turkey. 4. Department of Family Medicine, Ordu University Medical School, Ordu, Turkey. 5. Department of Cardiology, Ordu University Medical School, Ordu, Turkey. 6. Department of Emergency Medicine, Ministry of Health-Ordu University Education and Research Hospital, Ordu, Turkey. 7. Ataturk University Medical School Department of Cardiology, Erzurum, Turkey.
Abstract
AIM: We aimed to investigate the association between baseline red cell distribution width (RDW) level and the risk of stroke in patients with heart failure (HF). METHODS: A total of 153 consecutive patients with HF (New York Heart Association [NYHA] I-III and left ventricular ejection fraction of <40%) were included in this prospective study. All the patients were followed up for 1 year, and during this period the cerebrovascular disease was questioned. RESULTS: In matched population, using propensity score matching comparing patients with HF having stroke with patients without stroke, we found significantly increased basal RDW and serum uric acid. The receiver-operating characteristic curves of RDW for predicting stroke are performed. An RDW ≥ 15.2% measured on admission had 87% sensitivity and 74% specificity in predicting stroke in patients with HF (area under the curve: 0.923, 95% confidence interval: 0.852-0.994, P < .001). CONCLUSION: In conclusion, this study demonstrated that RDW may be important hematological indices for stroke in patients with HF using propensity score analysis.
AIM: We aimed to investigate the association between baseline red cell distribution width (RDW) level and the risk of stroke in patients with heart failure (HF). METHODS: A total of 153 consecutive patients with HF (New York Heart Association [NYHA] I-III and left ventricular ejection fraction of <40%) were included in this prospective study. All the patients were followed up for 1 year, and during this period the cerebrovascular disease was questioned. RESULTS: In matched population, using propensity score matching comparing patients with HF having stroke with patients without stroke, we found significantly increased basal RDW and serum uric acid. The receiver-operating characteristic curves of RDW for predicting stroke are performed. An RDW ≥ 15.2% measured on admission had 87% sensitivity and 74% specificity in predicting stroke in patients with HF (area under the curve: 0.923, 95% confidence interval: 0.852-0.994, P < .001). CONCLUSION: In conclusion, this study demonstrated that RDW may be important hematological indices for stroke in patients with HF using propensity score analysis.
Authors: Hasan Kara; Selim Degirmenci; Aysegul Bayir; Ahmet Ak; Murat Akinci; Ali Dogru; Fikret Akyurek; Seyit Ali Kayis Journal: Neuropsychiatr Dis Treat Date: 2015-03-18 Impact factor: 2.570