Literature DB >> 23792565

N-Terminal α-amino group modification of peptides by an oxime formation-exchange reaction sequence.

Karen Ka-Yan Kung1, Kong-Fan Wong, King-Chi Leung, Man-Kin Wong.   

Abstract

A site-specific and efficient method for N-terminal modification of peptides using oxone for selective oxidation of N-terminal α-amino groups of peptides to oximes followed by transoximation with O-substituted hydroxylamines has been developed.

Entities:  

Mesh：

Substances：

Year:  2013        PMID： 23792565     DOI： 10.1039/c3cc42261e

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  9 in total

Review 1.  Oximes and Hydrazones in Bioconjugation: Mechanism and Catalysis.

Authors:  Dominik K Kölmel; Eric T Kool
Journal:  Chem Rev       Date:  2017-06-22       Impact factor: 60.622

2.  Electrophilic Oxidation and [1,2]-Rearrangement of the Biindole Core of Birinapant.

Authors:  Yijun Deng; Thomas Haimowitz; Matthew G LaPorte; Susan R Rippin; Matthew D Alexander; Pavan Tirunahari Kumar; Mukta S Hendi; Yu-Hua Lee; Stephen M Condon
Journal:  ACS Med Chem Lett       Date:  2016-01-09       Impact factor: 4.345

3.  Functionalized quinolizinium-based fluorescent reagents for modification of cysteine-containing peptides and proteins.

Authors:  Karen Ka-Yan Kung; Cai-Fung Xu; Wa-Yi O; Qiong Yu; Sai-Fung Chung; Suet-Ying Tam; Yun-Chung Leung; Man-Kin Wong
Journal:  RSC Adv       Date:  2022-02-22       Impact factor: 3.361

Review 4.  Site-specific functionalization of proteins and their applications to therapeutic antibodies.

Authors:  Remko van Vught; Roland J Pieters; Eefjan Breukink
Journal:  Comput Struct Biotechnol J       Date:  2014-02-14       Impact factor: 7.271

5.  Selective N-terminal functionalization of native peptides and proteins.

Authors:  Diao Chen; Maria M Disotuar; Xiaochun Xiong; Yuanxiang Wang; Danny Hung-Chieh Chou
Journal:  Chem Sci       Date:  2017-01-09       Impact factor: 9.825

6.  Selective N-terminal acylation of peptides and proteins with a Gly-His tag sequence.

Authors:  Manuel C Martos-Maldonado; Christian T Hjuler; Kasper K Sørensen; Mikkel B Thygesen; Jakob E Rasmussen; Klaus Villadsen; Søren R Midtgaard; Stefan Kol; Sanne Schoffelen; Knud J Jensen
Journal:  Nat Commun       Date:  2018-08-17       Impact factor: 14.919

7.  Gold(I/III)-Phosphine Complexes as Potent Antiproliferative Agents.

Authors:  Jong Hyun Kim; Evan Reeder; Sean Parkin; Samuel G Awuah
Journal:  Sci Rep       Date:  2019-08-26       Impact factor: 4.379

Review 8.  From Synthesis to Characterization of Site-Selective PEGylated Proteins.

Authors:  Lisandra Herrera Belén; Carlota de Oliveira Rangel-Yagui; Jorge F Beltrán Lissabet; Brian Effer; Manuel Lee-Estevez; Adalberto Pessoa; Rodrigo L Castillo; Jorge G Farías
Journal:  Front Pharmacol       Date:  2019-12-18       Impact factor: 5.810

9.  Ketoxime peptide ligations: oxidative couplings of alkoxyamines to N-aryl peptides.

Authors:  Quibria A E Guthrie; Hailey A Young; Caroline Proulx
Journal:  Chem Sci       Date:  2019-08-29       Impact factor: 9.825
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.