Literature DB >> 23792484

Pancreatic cancer: Slow progression in the early stages.

Tsukasa Nakamura1, Koji Masuda, Shumpei Harada, Kiyokazu Akioka, Hirotaka Sako.   

Abstract

INTRODUCTION: The rates of pancreatic cancer development in the early stages of growth remain unclear; but it is generally believed that they demonstrate a rapid degree of progression. There is evidence to suggest that pancreatic cancers measuring less than 1cm demonstrate better survival rates, hence it is clear that detecting pancreatic cancers less than 1cm in size is of paramount importance. However, to date, there has been no scientifically adequate research to show the growth rate of small pancreatic cancers less than 1cm in the early stages. PRESENTATION OF CASE: We present the case of a 65-year-old woman whose small pancreatic cancer possibly demonstrated a slow progressive rate as it grew to an invasive carcinoma measuring 1cm diameter from over the 29 months. DISCUSSION: It is reasonable to assume that the progression of some pancreatic cancers until 1cm size, can take up to 29 months. During this silent period, it is crucial to detect such a small pancreatic cancer by means of the initial US and subsequent EUS and ERCP. It is clear, therefore, that clinicians have to be aware of the growth rate of small pancreatic cancers and in particular high risk patients should be encouraged to monitor size of the main pancreatic duct by means of US on regular basis.
CONCLUSION: This could give better outcomes for pancreatic cancer patients. Hopefully, by detecting these lethal, pancreatic cancers in their early stages, it will give us an extension of time to perform effective therapies.
Copyright © 2013 Surgical Associates Ltd. Published by Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Invasive ductal carcinoma; Main pancreatic duct dilatation; Pancreas; Slow progression; Small pancreatic cancer

Year:  2013        PMID: 23792484      PMCID: PMC3710898          DOI: 10.1016/j.ijscr.2013.04.040

Source DB:  PubMed          Journal:  Int J Surg Case Rep        ISSN: 2210-2612


  13 in total

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