| Literature DB >> 25356034 |
Welley S Loc1, Jill P Smith1, Gail Matters1, Mark Kester1, James H Adair1.
Abstract
With the incidence reports of pancreatic cancer increasing every year, research over the last several decades has been focused on the means to achieve early diagnosis in patients that are at a high risk of developing the malignancy. This review covers current strategies for managing pancreatic cancer and further discusses efforts in understanding the role of early onset symptoms leading to tumor progression. Recent investigations in this discussion include type 3c diabetes, selected biomarkers and pathways related to pancreatic intraepithelial neoplasia lesions, drug resistance, and advances in nanomedicine which may provide significant solutions for improving early detection and treatments in future medicine.Entities:
Keywords: Biomarkers; Diagnosis; Nanomedicine; Pancreatic cancer; Signaling pathways; Treatment
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Year: 2014 PMID: 25356034 PMCID: PMC4209537 DOI: 10.3748/wjg.v20.i40.14717
Source DB: PubMed Journal: World J Gastroenterol ISSN: 1007-9327 Impact factor: 5.742