Literature DB >> 25356034

Novel strategies for managing pancreatic cancer.

Welley S Loc1, Jill P Smith1, Gail Matters1, Mark Kester1, James H Adair1.   

Abstract

With the incidence reports of pancreatic cancer increasing every year, research over the last several decades has been focused on the means to achieve early diagnosis in patients that are at a high risk of developing the malignancy. This review covers current strategies for managing pancreatic cancer and further discusses efforts in understanding the role of early onset symptoms leading to tumor progression. Recent investigations in this discussion include type 3c diabetes, selected biomarkers and pathways related to pancreatic intraepithelial neoplasia lesions, drug resistance, and advances in nanomedicine which may provide significant solutions for improving early detection and treatments in future medicine.

Entities:  

Keywords:  Biomarkers; Diagnosis; Nanomedicine; Pancreatic cancer; Signaling pathways; Treatment

Mesh:

Substances:

Year:  2014        PMID: 25356034      PMCID: PMC4209537          DOI: 10.3748/wjg.v20.i40.14717

Source DB:  PubMed          Journal:  World J Gastroenterol        ISSN: 1007-9327            Impact factor:   5.742


  84 in total

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Review 3.  Cholecystokinin and pancreatic cancer: the chicken or the egg?

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Journal:  ACS Nano       Date:  2011-07-08       Impact factor: 15.881

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Journal:  J Gastrointest Oncol       Date:  2011-09

Review 6.  Calcium phosphate-based composite nanoparticles in bioimaging and therapeutic delivery applications.

Authors:  Amra Tabaković; Mark Kester; James H Adair
Journal:  Wiley Interdiscip Rev Nanomed Nanobiotechnol       Date:  2011-09-30

7.  Serum HCG beta and CA 72-4 are stronger prognostic factors than CEA, CA 19-9 and CA 242 in pancreatic cancer.

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8.  Conditional ablation of Notch signaling in pancreatic development.

Authors:  Hassan Nakhai; Jens T Siveke; Bettina Klein; Lidia Mendoza-Torres; Pawel K Mazur; Hana Algül; Freddy Radtke; Lothar Strobl; Ursula Zimber-Strobl; Roland M Schmid
Journal:  Development       Date:  2008-07-17       Impact factor: 6.868

Review 9.  Clinical pharmacology of 5-fluorouracil.

Authors:  R B Diasio; B E Harris
Journal:  Clin Pharmacokinet       Date:  1989-04       Impact factor: 6.447

10.  Precursor lesions of early onset pancreatic cancer.

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Journal:  Virchows Arch       Date:  2011-03-03       Impact factor: 4.064

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1.  Anticancer Effect of Ginger Extract against Pancreatic Cancer Cells Mainly through Reactive Oxygen Species-Mediated Autotic Cell Death.

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Journal:  PLoS One       Date:  2015-05-11       Impact factor: 3.240

2.  Increased platelet-to-lymphocytes ratio is associated with poor long-term prognosis in patients with pancreatic cancer after surgery.

Authors:  Jinming Yu; Zhaoyan Ding; Yuanming Yang; Shanli Liu
Journal:  Medicine (Baltimore)       Date:  2018-06       Impact factor: 1.889

3.  Obesity Is Associated with Early Onset of Gastrointestinal Cancers in California.

Authors:  Yen-Yi Juo; Melinda A Maggard Gibbons; Erik Dutson; Anne Y Lin; Jane Yanagawa; O Joe Hines; Guido Eibl; Yijun Chen
Journal:  J Obes       Date:  2018-09-19

Review 4.  Pancreatic cancer associated with obesity and diabetes: an alternative approach for its targeting.

Authors:  Ramesh Pothuraju; Satyanarayana Rachagani; Wade M Junker; Sanjib Chaudhary; Viswanathan Saraswathi; Sukhwinder Kaur; Surinder K Batra
Journal:  J Exp Clin Cancer Res       Date:  2018-12-19

5.  Cancer cell-derived interleukin-33 decoy receptor sST2 enhances orthotopic tumor growth in a murine pancreatic cancer model.

Authors:  Keizo Takenaga; Miho Akimoto; Nobuko Koshikawa; Hiroki Nagase
Journal:  PLoS One       Date:  2020-04-27       Impact factor: 3.240

6.  Antidiabetic adiponectin receptor agonist AdipoRon suppresses tumour growth of pancreatic cancer by inducing RIPK1/ERK-dependent necroptosis.

Authors:  Miho Akimoto; Riruke Maruyama; Yasunari Kawabata; Yoshitsugu Tajima; Keizo Takenaga
Journal:  Cell Death Dis       Date:  2018-07-23       Impact factor: 8.469

  6 in total

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