Martyn J Parker1. 1. Orthopaedic Research Fellow, Peterborough and Stamford Hospital NHS Foundation Trust, Department of Orthopaedics, Peterborough City Hospital, CBU P.O. Box 211, Core C, Bretton Gate, Peterborough PE3 9GZ, UK. Electronic address: Martyn.Parker@pbh-tr.nhs.uk.
Abstract
BACKGROUND: Debate exists as to what should be the transfusion threshold for patients with anaemia after hip fracture surgery. METHODS: A total of 200 patients aged 60 years and above with a haemoglobin level of between 8.0 and 9.5gdl(-1) after hip fracture surgery were randomised to receive a transfusion to raise the haemoglobin to at least 10.0gdl(-1) or not to have a transfusion unless definite symptoms of anaemia became apparent. Patients were followed up for 1 year. RESULTS: There was no statistically significant difference in the outcomes of mortality, hospital stay, regain of mobility or complications between the two groups. CONCLUSIONS: This study confirms other recent research studies which found that reducing the transfusion threshold to 8.0gdl(-1) appears to be a safe practice for this group of patients.
RCT Entities:
BACKGROUND: Debate exists as to what should be the transfusion threshold for patients with anaemia after hip fracture surgery. METHODS: A total of 200 patients aged 60 years and above with a haemoglobin level of between 8.0 and 9.5gdl(-1) after hip fracture surgery were randomised to receive a transfusion to raise the haemoglobin to at least 10.0gdl(-1) or not to have a transfusion unless definite symptoms of anaemia became apparent. Patients were followed up for 1 year. RESULTS: There was no statistically significant difference in the outcomes of mortality, hospital stay, regain of mobility or complications between the two groups. CONCLUSIONS: This study confirms other recent research studies which found that reducing the transfusion threshold to 8.0gdl(-1) appears to be a safe practice for this group of patients.
Authors: I Cortés-Puch; B M Wiley; J Sun; H G Klein; J Welsh; R L Danner; P Q Eichacker; C Natanson Journal: Transfus Med Date: 2018-04-19 Impact factor: 2.019
Authors: Jeffrey L Carson; Simon J Stanworth; Jane A Dennis; Marialena Trivella; Nareg Roubinian; Dean A Fergusson; Darrell Triulzi; Carolyn Dorée; Paul C Hébert Journal: Cochrane Database Syst Rev Date: 2021-12-21
Authors: Jeffrey L Carson; Simon J Stanworth; Nareg Roubinian; Dean A Fergusson; Darrell Triulzi; Carolyn Doree; Paul C Hebert Journal: Cochrane Database Syst Rev Date: 2016-10-12