Literature DB >> 23731364

Engineered proteins with Pumilio/fem-3 mRNA binding factor scaffold to manipulate RNA metabolism.

Yang Wang1, Zefeng Wang, Traci M Tanaka Hall.   

Abstract

Pumilio/fem-3 mRNA binding factor proteins are characterized by a sequence-specific RNA-binding domain. This unique single-stranded RNA recognition module, whose sequence specificity can be reprogrammed, has been fused with functional modules to engineer protein factors with various functions. We summarize the advances made with respect to developing RNA regulatory tools, as well as opportunities for the future.
© 2013. This article is a U.S. Government work and is in the public domain in the USA.

Entities:  

Keywords:  PUF protein; RNA; RNA localization; RNA regulation; RNA-binding protein; X-ray crystallography; protein engineering; protein-RNA interaction; splicing; translation

Mesh：

Substances：

Year:  2013        PMID： 23731364      PMCID： PMC3768134          DOI： 10.1111/febs.12367

Source DB:  PubMed          Journal:  FEBS J        ISSN： 1742-464X            Impact factor:   5.542


  81 in total

1.  Structure of Pumilio reveals similarity between RNA and peptide binding motifs.

Authors:  T A Edwards; S E Pyle; R P Wharton; A K Aggarwal
Journal:  Cell       Date:  2001-04-20       Impact factor: 41.582

2.  Patterns and plasticity in RNA-protein interactions enable recruitment of multiple proteins through a single site.

Authors:  Cary T Valley; Douglas F Porter; Chen Qiu; Zachary T Campbell; Traci M Tanaka Hall; Marvin Wickens
Journal:  Proc Natl Acad Sci U S A       Date:  2012-03-30       Impact factor: 11.205

3.  Structures of human Pumilio with noncognate RNAs reveal molecular mechanisms for binding promiscuity.

Authors:  Yogesh K Gupta; Deepak T Nair; Robin P Wharton; Aneel K Aggarwal
Journal:  Structure       Date:  2008-03-06       Impact factor: 5.006

4.  The Caenorhabditis elegans pumilio homolog, puf-9, is required for the 3'UTR-mediated repression of the let-7 microRNA target gene, hbl-1.

Authors:  Mona J Nolde; Nazli Saka; Kristy L Reinert; Frank J Slack
Journal:  Dev Biol       Date:  2007-03-03       Impact factor: 3.582

Review 5.  Protein-based nanocarriers as promising drug and gene delivery systems.

Authors:  Ahmed O Elzoghby; Wael M Samy; Nazik A Elgindy
Journal:  J Control Release       Date:  2012-04-28       Impact factor: 9.776

6.  Proliferating cells express mRNAs with shortened 3' untranslated regions and fewer microRNA target sites.

Authors:  Rickard Sandberg; Joel R Neilson; Arup Sarma; Phillip A Sharp; Christopher B Burge
Journal:  Science       Date:  2008-06-20       Impact factor: 47.728

7.  Recruitment of Nanos to hunchback mRNA by Pumilio.

Authors:  J Sonoda; R P Wharton
Journal:  Genes Dev       Date:  1999-10-15       Impact factor: 11.361

8.  Toward a general approach for RNA-templated hierarchical assembly of split-proteins.

Authors:  Jennifer L Furman; Ahmed H Badran; Oluyomi Ajulo; Jason R Porter; Cliff I Stains; David J Segal; Indraneel Ghosh
Journal:  J Am Chem Soc       Date:  2010-08-25       Impact factor: 15.419

Review 9.  Functions and regulation of RNA editing by ADAR deaminases.

Authors:  Kazuko Nishikura
Journal:  Annu Rev Biochem       Date:  2010       Impact factor: 23.643

10.  The Pumilio RNA-binding domain is also a translational regulator.

Authors:  R P Wharton; J Sonoda; T Lee; M Patterson; Y Murata
Journal:  Mol Cell       Date:  1998-05       Impact factor: 17.970
View more
  25 in total

Review 1.  Probing RNA-protein networks: biochemistry meets genomics.

Authors:  Zachary T Campbell; Marvin Wickens
Journal:  Trends Biochem Sci       Date:  2015-01-27       Impact factor: 13.807

2.  Synthetic RNA recognition motifs that selectively recognize HIV-1 trans-activation response element hairpin RNA.

Authors:  Brett D Blakeley; Brian R McNaughton
Journal:  ACS Chem Biol       Date:  2014-03-25       Impact factor: 5.100

3.  A Nucleolar PUF RNA-binding Protein with Specificity for a Unique RNA Sequence.

Authors:  Chi Zhang; Douglas G Muench
Journal:  J Biol Chem       Date:  2015-10-20       Impact factor: 5.157

4.  PUM1 is a biphasic negative regulator of innate immunity genes by suppressing LGP2.

Authors:  Yonghong Liu; Linlin Qu; Yuanyuan Liu; Bernard Roizman; Grace Guoying Zhou
Journal:  Proc Natl Acad Sci U S A       Date:  2017-07-31       Impact factor: 11.205

5.  Expanding RNA binding specificity and affinity of engineered PUF domains.

Authors:  Yang-Yang Zhao; Miao-Wei Mao; Wen-Jing Zhang; Jue Wang; Hai-Tao Li; Yi Yang; Zefeng Wang; Jia-Wei Wu
Journal:  Nucleic Acids Res       Date:  2018-05-18       Impact factor: 16.971

Review 6.  The potential of engineered eukaryotic RNA-binding proteins as molecular tools and therapeutics.

Authors:  Carl R Shotwell; John D Cleary; J Andrew Berglund
Journal:  Wiley Interdiscip Rev RNA       Date:  2019-11-03       Impact factor: 9.957

Review 7.  Engineering RNA-binding proteins for biology.

Authors:  Yu Chen; Gabriele Varani
Journal:  FEBS J       Date:  2013-07-05       Impact factor: 5.542

8.  A divergent Pumilio repeat protein family for pre-rRNA processing and mRNA localization.

Authors:  Chen Qiu; Kathleen L McCann; Robert N Wine; Susan J Baserga; Traci M Tanaka Hall
Journal:  Proc Natl Acad Sci U S A       Date:  2014-12-15       Impact factor: 11.205

Review 9.  Specificity and nonspecificity in RNA-protein interactions.

Authors:  Eckhard Jankowsky; Michael E Harris
Journal:  Nat Rev Mol Cell Biol       Date:  2015-08-19       Impact factor: 94.444

10.  5'-UTR SNP of FGF13 causes translational defect and intellectual disability.

Authors:  Xingyu Pan; Jingrong Zhao; Zhiying Zhou; Jijun Chen; Zhenxing Yang; Yuxuan Wu; Meizhu Bai; Yang Jiao; Yun Yang; Xuye Hu; Tianling Cheng; Qianyun Lu; Bin Wang; Chang-Lin Li; Ying-Jin Lu; Lei Diao; Yan-Qing Zhong; Jing Pan; Jianmin Zhu; Hua-Sheng Xiao; Zi-Long Qiu; Jinsong Li; Zefeng Wang; Jingyi Hui; Lan Bao; Xu Zhang
Journal:  Elife       Date:  2021-06-29       Impact factor: 8.140
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.