Literature DB >> 23730555

The optimization of phenolic compounds extraction from cactus pear (Opuntia ficus-indica) skin in a reflux system using response surface methodology.

Aguirre Joya Jorge1, De La Garza Toledo Heliodoro, Zugasti Cruz Alejandro, Belmares Cerda Ruth, Aguilar Cristóbal Noé.   

Abstract

OBJECTIVE: To extract, quantify, and evaluate the phenolic content in Opuntia ficus-indica skin for their antioxidant capacity with three different methods (ABTS, DPPH, and lipid oxidation) and to optimize the extraction conditions (time, temperature and ethanol concentration) in a reflux system.
METHODS: The extraction process was done using a reflux system. A San Cristobal II experimental design with three variables and three levels was used. The variables evaluated were time of extraction (h), concentration of ethanol (%, v/v) and temperature (°C). The extraction process was optimized using a response surface methodology.
RESULTS: It was observed that at higher temperature more phenolic compounds were extracted, but the antioxidant capacity was decreased. The optimum conditions for phenolic compounds extraction and antioxidant capacity mixing the three methods were as follows: 45% of ethanol, 80 °C and 2 hours of extraction. Values obtained in our results are little higher that other previously reported.
CONCLUSIONS: It can be concluded the by-products of Opuntia ficus-indica represent a good source of natural antioxidants with possible applications in food, cosmetics or drugs industries.

Entities:  

Keywords:  Antioxidants; Opuntia ficus-indica; Prickly pear; Reflux, Phenolics; Response surface methodology

Mesh:

Substances:

Year:  2013        PMID: 23730555      PMCID: PMC3644570          DOI: 10.1016/S2221-1691(13)60093-3

Source DB:  PubMed          Journal:  Asian Pac J Trop Biomed        ISSN: 2221-1691


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