Literature DB >> 23716038

Before and after hip fracture, vitamin D deficiency may not be treated sufficiently.

S Maier1, E Sidelnikov, B Dawson-Hughes, A Egli, R Theiler, A Platz, H B Staehelin, H-P Simmen, C Meier, W Dick, D Grob, A von Eckardstein, H A Bischoff-Ferrari.   

Abstract

UNLABELLED: Our findings show that only about 20% of seniors receive vitamin D supplementation prior to their index hip fracture or after the event. We further confirm the high prevalence of severe vitamin D deficiency in this population and show that those who receive supplementation have significantly higher 25-hydroxyvitamin D (25(OH)D) status.
INTRODUCTION: The aim of this study is to assess current practice in pre- and post-hip fracture care practice with respect to vitamin D supplementation.
METHODS: We surveyed 1,090 acute hip fracture patients age 65 and older admitted to acute care for hip fracture repair; 844 had serum 25-hydroxyvitamin D levels measured upon admission to acute care, and 362 agreed to be followed at 12 month after their hip fracture. Prevalence of vitamin D supplementation was assessed upon admission to acute care (at the time of hip fracture), upon discharge from acute care, and at 6 and 12 months follow-up.
RESULTS: Of 1,090 acute hip fracture patients (mean age 85 years, 78% women, 59 % community-dwelling), 19% had received any dose of vitamin D prior to the index hip fracture, 27% (of 854 assessed) at discharge from acute care, 22 % (of 321 assessed) at 6 month, and 21% (of 285 assessed) at 12 month after their hip fracture. At the time of fracture, 45% had 25(OH)D levels below 10 ng/ml, 81% had levels below 20 ng/ml, and 96% had levels below 30 ng/ml. Notably, 25(OH)D levels did not differ by season or gender but were significantly higher among 164 hip fracture patients, with any vitamin D supplementation compared with 680 without supplementation (19.9 versus 10.8 ng/ml; p < 0.0001).
CONCLUSION: Only about 20% of seniors receive vitamin D at the time of their fracture and after the event. This is despite the documented 81% prevalence of vitamin D deficiency. Interdisciplinary efforts may be warranted to improve vitamin D supplementation in seniors both before a hip fracture occurs and after.

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Year:  2013        PMID: 23716038     DOI: 10.1007/s00198-013-2400-z

Source DB:  PubMed          Journal:  Osteoporos Int        ISSN: 0937-941X            Impact factor:   4.507


  34 in total

1.  Occult vitamin D deficiency in postmenopausal US women with acute hip fracture.

Authors:  M S LeBoff; L Kohlmeier; S Hurwitz; J Franklin; J Wright; J Glowacki
Journal:  JAMA       Date:  1999-04-28       Impact factor: 56.272

Review 2.  Vitamin D deficiency.

Authors:  Michael F Holick
Journal:  N Engl J Med       Date:  2007-07-19       Impact factor: 91.245

3.  Recovery from hip fracture in eight areas of function.

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Journal:  J Gerontol A Biol Sci Med Sci       Date:  2000-09       Impact factor: 6.053

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Journal:  Epidemiol Rev       Date:  1985       Impact factor: 6.222

5.  Half of the patients with an acute hip fracture suffer from hypovitaminosis D: a prospective study in southeastern Finland.

Authors:  Ilona Nurmi; Juha-Pekka Kaukonen; Peter Lüthje; Helena Naboulsi; Salla Tanninen; Matti Kataja; Maija-Leena Kallio; Marjatta Leppilampi
Journal:  Osteoporos Int       Date:  2005-08-24       Impact factor: 4.507

6.  Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline.

Authors:  Michael F Holick; Neil C Binkley; Heike A Bischoff-Ferrari; Catherine M Gordon; David A Hanley; Robert P Heaney; M Hassan Murad; Connie M Weaver
Journal:  J Clin Endocrinol Metab       Date:  2011-06-06       Impact factor: 5.958

7.  Mild to moderate cognitive impairment is a major risk factor for mortality and nursing home admission in the first year after hip fracture.

Authors:  F Schaller; E Sidelnikov; R Theiler; A Egli; H B Staehelin; W Dick; B Dawson-Hughes; D Grob; A Platz; U Can; H A Bischoff-Ferrari
Journal:  Bone       Date:  2012-06-12       Impact factor: 4.398

8.  Seasonal variation, hip fracture and vitamin D levels in Southern Tasmania.

Authors:  C A Inderjeeth; T Barrett; Y Al-Lahham; J Mulford; F Nicklason; C Reberger
Journal:  N Z Med J       Date:  2002-04-26

Review 9.  Benefit-risk assessment of vitamin D supplementation.

Authors:  H A Bischoff-Ferrari; A Shao; B Dawson-Hughes; J Hathcock; E Giovannucci; W C Willett
Journal:  Osteoporos Int       Date:  2009-12-03       Impact factor: 4.507

Review 10.  Fall prevention with supplemental and active forms of vitamin D: a meta-analysis of randomised controlled trials.

Authors:  H A Bischoff-Ferrari; B Dawson-Hughes; H B Staehelin; J E Orav; A E Stuck; R Theiler; J B Wong; A Egli; D P Kiel; J Henschkowski
Journal:  BMJ       Date:  2009-10-01
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  6 in total

1.  Vitamin D insufficiency over 5 years is associated with increased fracture risk-an observational cohort study of elderly women.

Authors:  D Buchebner; F McGuigan; P Gerdhem; J Malm; M Ridderstråle; K Akesson
Journal:  Osteoporos Int       Date:  2014-08-13       Impact factor: 4.507

2.  The use of cholecalciferol in patients with hip fracture.

Authors:  Luisella Cianferotti; Simone Parri; Giorgio Gronchi; Roberto Civinini; Maria Luisa Brandi
Journal:  Clin Cases Miner Bone Metab       Date:  2017-05-30

3.  A Resident-led Initiative Improves Screening and Treatment for Vitamin D Deficiency in Patients with Hip Fractures.

Authors:  Drew A Lansdown; Amanda Whitaker; Rosanna Wustrack; Aenor Sawyer; Erik N Hansen
Journal:  Clin Orthop Relat Res       Date:  2016-08-22       Impact factor: 4.176

4.  Suspected coexistent osteoporosis and osteomalacia with atraumatic bilateral neck of femur fractures in a 53-year-old man without apparent risk factors.

Authors:  Joshua De Marchi; Raazi Bajwa; Sinead Noelle Duggan; Paul Magill
Journal:  BMJ Case Rep       Date:  2014-09-04

5.  Vitamin D deficiency in adult fracture patients: prevalence and risk factors.

Authors:  E A Gorter; P Krijnen; I B Schipper
Journal:  Eur J Trauma Emerg Surg       Date:  2015-07-21       Impact factor: 3.693

Review 6.  The role of vitamin D and vitamin D deficiency in orthopaedics and traumatology-a narrative overview of the literature.

Authors:  Gerrit S Maier; Manuel Weissenberger; Maximilian Rudert; Klaus E Roth; Konstantin Horas
Journal:  Ann Transl Med       Date:  2021-06
  6 in total

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