Literature DB >> 23678458

The role of oral controlled release matrix tablets in drug delivery systems.

Ali Nokhodchi1, Shaista Raja, Pryia Patel, Kofi Asare-Addo.   

Abstract

Formulations that are able to control the release of drug have become an integral part of the pharmaceutical industry. In particular oral drug delivery has been the focus of pharmaceutical research for many years. This type of drug delivery has been at the centre of research due to its many benefits over conventional dosage. The focus of this review is on matrix tablets due to their widely use and simplicity of the formulation. This includes the discussion of various types of matrix tablets and factors affecting the drug release from these formulations. The mechanism of drug release from HPMC matrices is also discussed.

Keywords:  Diffusion; Erosion; Kinetics of Drug Release; Matrix Tablet; Sustained Release

Year:  2012        PMID: 23678458      PMCID: PMC3648939          DOI: 10.5681/bi.2012.027

Source DB:  PubMed          Journal:  Bioimpacts        ISSN: 2228-5652


  52 in total

1.  Spatially resolved solvent interaction with glassy HPMC polymers studied by magnetic resonance microscopy.

Authors:  Jadwiga Tritt-Goc; Joanna Kowalczuk
Journal:  Solid State Nucl Magn Reson       Date:  2005-09       Impact factor: 2.293

2.  Molecular analysis of drug delivery systems controlled by dissolution of the polymer carrier.

Authors:  B Narasimhan; N A Peppas
Journal:  J Pharm Sci       Date:  1997-03       Impact factor: 3.534

3.  In situ cross-linking of sodium alginate with calcium and aluminum ions to sustain the release of theophylline from polymeric matrices.

Authors:  Ali Nokhodchi; Anish Tailor
Journal:  Farmaco       Date:  2004-12

4.  Investigation of factors influencing release of solid drug dispersed in inert matrices.

Authors:  S J Desai; A P Simonelli; W I Higuchi
Journal:  J Pharm Sci       Date:  1965-10       Impact factor: 3.534

5.  Rheological properties and diffusion dissolution behaviour of hydrophilic polymers.

Authors:  C Caramella; F Ferrari; M C Bonferoni; M Ronchi; P Colombo
Journal:  Boll Chim Farm       Date:  1989-10

6.  Hydrophilic matrices for controlled drug delivery: an improved mathematical model to predict the resulting drug release kinetics (the "sequential layer" model).

Authors:  J Siepmann; N A Peppas
Journal:  Pharm Res       Date:  2000-10       Impact factor: 4.200

7.  Modulation of tramadol release from a hydrophobic matrix: implications of formulations and processing variables.

Authors:  B S Sudha; B K Sridhar; A Srinatha
Journal:  AAPS PharmSciTech       Date:  2010-03-19       Impact factor: 3.246

8.  The influence of excipients on drug release from hydroxypropyl methylcellulose matrices.

Authors:  Marina Levina; Ali R Rajabi-Siahboomi
Journal:  J Pharm Sci       Date:  2004-11       Impact factor: 3.534

9.  A new model describing the swelling and drug release kinetics from hydroxypropyl methylcellulose tablets.

Authors:  J Siepmann; K Podual; M Sriwongjanya; N A Peppas; R Bodmeier
Journal:  J Pharm Sci       Date:  1999-01       Impact factor: 3.534

10.  Variables influencing drug release from layered matrix system comprising hydroxypropyl methylcellulose.

Authors:  Thawatchai Phaechamud
Journal:  AAPS PharmSciTech       Date:  2008-05-24       Impact factor: 3.246

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  18 in total

1.  An investigation into the stabilization of diltiazem HCl release from matrices made from aged polyox powders.

Authors:  Saeed Shojaee; Kofi Asare-Addo; Waseem Kaialy; Ali Nokhodchi; Iain Cumming
Journal:  AAPS PharmSciTech       Date:  2013-07-31       Impact factor: 3.246

2.  Oral Drug Delivery Technologies-A Decade of Developments.

Authors:  G Kaur; M Arora; M N V Ravi Kumar
Journal:  J Pharmacol Exp Ther       Date:  2019-04-22       Impact factor: 4.030

3.  Assessing bioequivalence of generic modified-release antiepileptic drugs.

Authors:  Emily L Johnson; Yi-Ting Chang; Barbara Davit; Barry E Gidal; Gregory L Krauss
Journal:  Neurology       Date:  2016-03-25       Impact factor: 9.910

4.  Denatured Whey Protein Powder as a New Matrix Excipient: Design and Evaluation of Mucoadhesive Tablets for Sustained Drug Release Applications.

Authors:  Hassana Hsein; Ghislain Garrait; Fahima Tamani; Eric Beyssac; Valérie Hoffart
Journal:  Pharm Res       Date:  2016-12-21       Impact factor: 4.200

5.  A Physiologically Based Pharmacokinetic Model for Optimally Profiling Lamotrigine Disposition and Drug-Drug Interactions.

Authors:  Todd M Conner; Ronald C Reed; Tao Zhang
Journal:  Eur J Drug Metab Pharmacokinet       Date:  2019-06       Impact factor: 2.441

6.  An Integrative QbD Approach for the Development and Optimization of Controlled Release Compressed Coated Formulation of Water-Soluble Drugs.

Authors:  Viral Shah; Ekta Khambhla; Manish Nivsarkar; Riddhi Trivedi; Rakesh K Patel
Journal:  AAPS PharmSciTech       Date:  2022-04-22       Impact factor: 3.246

7.  Exploratory studies in heat-assisted continuous twin-screw dry granulation: A novel alternative technique to conventional dry granulation.

Authors:  Venkata Raman Kallakunta; Hemlata Patil; Roshan Tiwari; Xingyou Ye; Sampada Upadhye; Ronald S Vladyka; Sandeep Sarabu; Dong Wuk Kim; Suresh Bandari; Michael A Repka
Journal:  Int J Pharm       Date:  2018-11-17       Impact factor: 5.875

8.  Effect of formulation and process variables on lipid based sustained release tablets via continuous twin screw granulation: A comparative study.

Authors:  Venkata Raman Kallakunta; Roshan Tiwari; Sandeep Sarabu; Suresh Bandari; Michael A Repka
Journal:  Eur J Pharm Sci       Date:  2018-05-14       Impact factor: 4.384

Review 9.  A Clinician's Guide to Oral Extended-Release Drug Delivery Systems in Epilepsy.

Authors:  James W Wheless; Stephanie J Phelps
Journal:  J Pediatr Pharmacol Ther       Date:  2018 Jul-Aug

10.  Design, Formulation and In Vitro Evaluation of Sustained-release Tablet Formulations of Levosulpiride.

Authors:  Muhammad Samie; Sajid Bashir; Jabbar Abbas; Samiullah Khan; Nargis Aman; Habibullah Jan; Naveed Muhammad
Journal:  Turk J Pharm Sci       Date:  2018-11-20
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