Literature DB >> 23666786

A highly step-economical synthesis of dictyostatin.

Stephen Ho1, Cyril Bucher, James L Leighton.   

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Year:  2013        PMID: 23666786      PMCID: PMC3812691          DOI: 10.1002/anie.201302565

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN: 1433-7851            Impact factor:   15.336


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  45 in total

1.  Total synthesis of (-)-dictyostatin.

Authors:  Gregory W O'Neil; Andrew J Phillips
Journal:  J Am Chem Soc       Date:  2006-04-26       Impact factor: 15.419

2.  Total synthesis of potential antitumor agent, (-)-dictyostatin.

Authors:  P Veeraraghavan Ramachandran; Amit Srivastava; Debasis Hazra
Journal:  Org Lett       Date:  2007-01-04       Impact factor: 6.005

3.  Synthesis and biological evaluation of 10,11-dihydrodictyostatin, a potent analogue of the marine anticancer agent dictyostatin.

Authors:  Ian Paterson; Nicola M Gardner; Karine G Poullennec; Amy E Wright
Journal:  J Nat Prod       Date:  2007-12-15       Impact factor: 4.050

4.  Streamlined syntheses of (-)-dictyostatin, 16-desmethyl-25,26-dihydrodictyostatin, and 6-epi-16-desmethyl-25,26-dihydrodictyostatin.

Authors:  Wei Zhu; María Jiménez; Won-Hyuk Jung; Daniel P Camarco; Raghavan Balachandran; Andreas Vogt; Billy W Day; Dennis P Curran
Journal:  J Am Chem Soc       Date:  2010-07-07       Impact factor: 15.419

5.  A practical synthesis of (+)-discodermolide and analogues: fragment union by complex aldol reactions.

Authors:  I Paterson; G J Florence; K Gerlach; J P Scott; N Sereinig
Journal:  J Am Chem Soc       Date:  2001-10-03       Impact factor: 15.419

6.  Enantioselective hydroformylation of N-vinyl carboxamides, allyl carbamates, and allyl ethers using chiral diazaphospholane ligands.

Authors:  Richard I McDonald; Gene W Wong; Ram P Neupane; Shannon S Stahl; Clark R Landis
Journal:  J Am Chem Soc       Date:  2010-10-13       Impact factor: 15.419

7.  The bound conformation of microtubule-stabilizing agents: NMR insights into the bioactive 3D structure of discodermolide and dictyostatin.

Authors:  Angeles Canales; Ruth Matesanz; Nicola M Gardner; José Manuel Andreu; Ian Paterson; J Fernando Díaz; Jesús Jiménez-Barbero
Journal:  Chemistry       Date:  2008       Impact factor: 5.236

8.  Toward a more step-economical and scalable synthesis of spongistatin 1 to facilitate cancer drug development efforts.

Authors:  Samuel K Reznik; James L Leighton
Journal:  Chem Sci       Date:  2013-04-01       Impact factor: 9.825

9.  Chemoenzymatic synthesis of the C10-C23 segment of dictyostatin.

Authors:  Evgeny Prusov; Hartmut Röhm; Martin E Maier
Journal:  Org Lett       Date:  2006-03-16       Impact factor: 6.005

10.  Direct and highly regioselective and enantioselective allylation of β-diketones.

Authors:  Wesley A Chalifoux; Samuel K Reznik; James L Leighton
Journal:  Nature       Date:  2012-07-05       Impact factor: 49.962

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  12 in total

1.  Evolution of an Efficient and Scalable Nine-Step (Longest Linear Sequence) Synthesis of Zincophorin Methyl Ester.

Authors:  Liang-An Chen; Melissa A Ashley; James L Leighton
Journal:  J Am Chem Soc       Date:  2017-03-15       Impact factor: 15.419

Review 2.  Conformation-activity relationships of polyketide natural products.

Authors:  Erik M Larsen; Matthew R Wilson; Richard E Taylor
Journal:  Nat Prod Rep       Date:  2015-08       Impact factor: 13.423

3.  Total Synthesis and Structural Reassignment of Lyngbyaloside C Highlighted by Intermolecular Ketene Esterification.

Authors:  Chia-Fu Chang; Eric Stefan; Richard E Taylor
Journal:  Chemistry       Date:  2015-06-23       Impact factor: 5.236

4.  Synthesis of (+)-discodermolide by catalytic stereoselective borylation reactions.

Authors:  Zhiyong Yu; Robert J Ely; James P Morken
Journal:  Angew Chem Int Ed Engl       Date:  2014-07-15       Impact factor: 15.336

Review 5.  Recent progress with microtubule stabilizers: new compounds, binding modes and cellular activities.

Authors:  Cristina C Rohena; Susan L Mooberry
Journal:  Nat Prod Rep       Date:  2014-03       Impact factor: 13.423

6.  Enantioselective Hydroformylation of 1-Alkenes with Commercial Ph-BPE Ligand.

Authors:  Zhiyong Yu; Meredith S Eno; Alexandra H Annis; James P Morken
Journal:  Org Lett       Date:  2015-06-19       Impact factor: 6.005

7.  A "methyl extension" strategy for polyketide natural product linker site validation and its application to dictyostatin.

Authors:  Stephen Ho; Dan L Sackett; James L Leighton
Journal:  J Am Chem Soc       Date:  2015-11-03       Impact factor: 15.419

8.  Beyond the Roche ester: a new approach to polypropionate stereotriad synthesis.

Authors:  Corinne N Foley; James L Leighton
Journal:  Org Lett       Date:  2014-02-06       Impact factor: 6.005

9.  Design and 22-step synthesis of highly potent D-ring modified and linker-equipped analogs of spongistatin 1.

Authors:  Linda M Suen; Makeda A Tekle-Smith; Kevin S Williamson; Joshua R Infantine; Samuel K Reznik; Paul S Tanis; Tyler D Casselman; Dan L Sackett; James L Leighton
Journal:  Nat Commun       Date:  2018-11-09       Impact factor: 14.919

Review 10.  Marine Invertebrate Metabolites with Anticancer Activities: Solutions to the "Supply Problem".

Authors:  Nelson G M Gomes; Ramesh Dasari; Sunena Chandra; Robert Kiss; Alexander Kornienko
Journal:  Mar Drugs       Date:  2016-05-21       Impact factor: 5.118

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