| Literature DB >> 23664890 |
Poornima Budime Santhosh1, Nataša Poklar Ulrih.
Abstract
Iron-oxide nanoparticles of small dimensions that have superparamagnetic properties show immense potential to revolutionize the future of cancer theranostics, the combinatorial diagnosis and therapeutic approach towards cancer. Superparamagnetic iron-oxide nanoparticles (SPIONs) have unique magnetic properties, due to which they show excellent tumor-targeting efficiency, and this paves the way for effective personalized cancer treatment. The aim of this review is to focus on the ability of SPIONs to perform multiple roles in the field of cancer biology, such as in diagnosis, monitoring, targeting and therapy. Also, other topics are discussed, including the synthesis of SPIONs, the challenges and recent advances.Entities:
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Year: 2013 PMID: 23664890 DOI: 10.1016/j.canlet.2013.04.032
Source DB: PubMed Journal: Cancer Lett ISSN: 0304-3835 Impact factor: 8.679