BACKGROUND: In addition to the core symptoms, attention deficit hyperactivity disorder (ADHD) is associated with poor emotion regulation. There is some evidence that children and young adults with ADHD have lower omega-3 levels and that supplementation with omega-3 can improve both ADHD and affective symptoms. We therefore investigated differences between ADHD and non-ADHD children in omega-3/6 fatty acid plasma levels and the relationship between those indices and emotion-elicited event-related potentials (ERPs). METHODS: Children/adolescents with (n=31) and without ADHD (n=32) were compared in their plasma omega-3/6 indices and corresponding ERPs during an emotion processing task. RESULTS: Children with ADHD had lower mean omega-3/6 and ERP abnormalities in emotion processing, independent of emotional valence relative to control children. ERP abnormalities were significantly associated with lower omega-3 levels in the ADHD group. CONCLUSIONS: The findings reveal for the first time that lower omega-3 fatty acids are associated with impaired emotion processing in ADHD children.
BACKGROUND: In addition to the core symptoms, attention deficit hyperactivity disorder (ADHD) is associated with poor emotion regulation. There is some evidence that children and young adults with ADHD have lower omega-3 levels and that supplementation with omega-3 can improve both ADHD and affective symptoms. We therefore investigated differences between ADHD and non-ADHDchildren in omega-3/6 fatty acid plasma levels and the relationship between those indices and emotion-elicited event-related potentials (ERPs). METHODS:Children/adolescents with (n=31) and without ADHD (n=32) were compared in their plasma omega-3/6 indices and corresponding ERPs during an emotion processing task. RESULTS:Children with ADHD had lower mean omega-3/6 and ERP abnormalities in emotion processing, independent of emotional valence relative to control children. ERP abnormalities were significantly associated with lower omega-3 levels in the ADHD group. CONCLUSIONS: The findings reveal for the first time that lower omega-3 fatty acids are associated with impaired emotion processing in ADHDchildren.
Authors: R W Greene; J Biederman; S V Faraone; M C Monuteaux; E Mick; E P DuPre; C S Fine; J C Goring Journal: J Am Acad Child Adolesc Psychiatry Date: 2001-06 Impact factor: 8.829
Authors: Ke Liao; Bruce D McCandliss; Susan E Carlson; John Colombo; D Jill Shaddy; Elizabeth H Kerling; Rebecca J Lepping; Wichian Sittiprapaporn; Carol L Cheatham; Kathleen M Gustafson Journal: Dev Sci Date: 2016-10-16
Authors: Leslie R Miller; Matthew J Jorgensen; Jay R Kaplan; Michael C Seeds; Elaheh Rahbar; Timothy M Morgan; Andrea Welborn; Sarah M Chilton; Julianne Gillis; Austin Hester; Mae Rukstalis; Susan Sergeant; Floyd H Chilton Journal: Physiol Behav Date: 2015-12-17