OBJECTIVE: To evaluate the association between serum bisphenol-A (BPA) concentration and sex hormone levels in men. DESIGN: Cross-sectional study. SETTING: Not applicable. PATIENT(S): A total of 290 men with or without BPA exposure in the workplace. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Serum sex hormone levels. RESULT(S): After adjustment for potential confounders using linear regression, increasing serum BPA concentration was statistically significantly associated with [1] decreased androstenedione levels, [2] decreased free testosterone levels, [3] decreased free androgen index, and [4] increased sex hormone-binding globulin levels. Comparison of hormone levels between workers exposed and unexposed to BPA showed similar associations. CONCLUSION(S): Exposure to a high BPA level may impact sex hormone levels in men.
OBJECTIVE: To evaluate the association between serum bisphenol-A (BPA) concentration and sex hormone levels in men. DESIGN: Cross-sectional study. SETTING: Not applicable. PATIENT(S): A total of 290 men with or without BPA exposure in the workplace. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Serum sex hormone levels. RESULT(S): After adjustment for potential confounders using linear regression, increasing serum BPA concentration was statistically significantly associated with [1] decreased androstenedione levels, [2] decreased free testosterone levels, [3] decreased free androgen index, and [4] increased sex hormone-binding globulin levels. Comparison of hormone levels between workers exposed and unexposed to BPA showed similar associations. CONCLUSION(S): Exposure to a high BPA level may impact sex hormone levels in men.
Authors: Lílian Cristina Pereira; Alecsandra Oliveira de Souza; Mariana Furio Franco Bernardes; Murilo Pazin; Maria Júlia Tasso; Paulo Henrique Pereira; Daniel Junqueira Dorta Journal: Environ Sci Pollut Res Int Date: 2015-07-24 Impact factor: 4.223
Authors: Cynthia J Hines; Matthew V Jackson; James A Deddens; John C Clark; Xiaoyun Ye; Annette L Christianson; Juliana W Meadows; Antonia M Calafat Journal: Ann Work Expo Health Date: 2017-03-01 Impact factor: 2.179
Authors: Cynthia J Hines; Annette L Christianson; Matthew V Jackson; Xiaoyun Ye; Jack R Pretty; James E Arnold; Antonia M Calafat Journal: Ann Work Expo Health Date: 2018-08-13 Impact factor: 2.179
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Authors: Martha León-Olea; Christopher J Martyniuk; Edward F Orlando; Mary Ann Ottinger; Cheryl Rosenfeld; Jennifer Wolstenholme; Vance L Trudeau Journal: Gen Comp Endocrinol Date: 2014-02-13 Impact factor: 2.822