Literature DB >> 23625516

Elongation of textile pelvic floor implants under load is related to complete loss of effective porosity, thereby favoring incorporation in scar plates.

Jens Otto1, E Kaldenhoff, R Kirschner-Hermanns, Thomas Mühl, Uwe Klinge.   

Abstract

Use of textile structures for reinforcement of pelvic floor structures has to consider mechanical forces to the implant, which are quite different to the tension free conditions of the abdominal wall. Thus, biomechanical analysis of textile devices has to include the impact of strain on stretchability and effective porosity. Prolift(®) and Prolift + M(®), developed for tension free conditions, were tested by measuring stretchability and effective porosity applying mechanical strain. For comparison, we used Dynamesh-PR4(®), which was designed for pelvic floor repair to withstand mechanical strain. Prolift(®) at rest showed moderate porosity with little stretchability but complete loss of effective porosity at strain of 4.9 N/cm. Prolift + M(®) revealed an increased porosity at rest, but at strain showed high stretchability, with subsequent loss of effective porosity at strain of 2.5 N/cm. Dynamesh PR4(®) preserved its high porosity even under strain, but as consequence of limited stretchability. Though in tension free conditions Prolift(®) and Prolift + M(®) can be considered as large pore class I meshes, application of mechanical strain rapidly lead to collapse of pores. The loss of porosity at mechanical stress can be prevented by constructions with high structural stability. Assessment of porosity under strain was found helpful to define requirements for pelvic floor devices. Clinical studies have to prove whether devices with high porosity as well as high structural stability can improve the patients' outcome.
Copyright © 2013 Wiley Periodicals, Inc.

Entities:  

Keywords:  PP; PVDF; biomechanics; effective porosity; mesh implant; pelvic floor repair

Mesh:

Year:  2013        PMID: 23625516     DOI: 10.1002/jbm.a.34767

Source DB:  PubMed          Journal:  J Biomed Mater Res A        ISSN: 1549-3296            Impact factor:   4.396


  13 in total

1.  The impact of boundary conditions on surface curvature of polypropylene mesh in response to uniaxial loading.

Authors:  William R Barone; Rouzbeh Amini; Spandan Maiti; Pamela A Moalli; Steven D Abramowitch
Journal:  J Biomech       Date:  2015-03-16       Impact factor: 2.712

2.  Impact of prolapse meshes on the metabolism of vaginal extracellular matrix in rhesus macaque.

Authors:  Rui Liang; Wenjun Zong; Stacy Palcsey; Steven Abramowitch; Pamela A Moalli
Journal:  Am J Obstet Gynecol       Date:  2014-08-12       Impact factor: 8.661

3.  Impact of polypropylene prolapse mesh on vaginal smooth muscle in rhesus macaque.

Authors:  Rebecca M Shaffer; Rui Liang; Katrina Knight; Charelle M Carter-Brooks; Steven Abramowitch; Pamela A Moalli
Journal:  Am J Obstet Gynecol       Date:  2019-05-16       Impact factor: 8.661

4.  Preventing Mesh Pore Collapse by Designing Mesh Pores With Auxetic Geometries: A Comprehensive Evaluation Via Computational Modeling.

Authors:  Katrina M Knight; Pamela A Moalli; Steven D Abramowitch
Journal:  J Biomech Eng       Date:  2018-05-01       Impact factor: 2.097

Review 5.  Host-biomaterial interactions in mesh complications after pelvic floor reconstructive surgery.

Authors:  Roxanna E Abhari; Matthew L Izett-Kay; Hayley L Morris; Rufus Cartwright; Sarah J B Snelling
Journal:  Nat Rev Urol       Date:  2021-09-20       Impact factor: 14.432

6.  Mesh deformation: A mechanism underlying polypropylene prolapse mesh complications in vivo.

Authors:  Katrina M Knight; Gabrielle E King; Stacy L Palcsey; Amanda Suda; Rui Liang; Pamela A Moalli
Journal:  Acta Biomater       Date:  2022-06-06       Impact factor: 10.633

7.  Host response to synthetic mesh in women with mesh complications.

Authors:  Alexis L Nolfi; Bryan N Brown; Rui Liang; Stacy L Palcsey; Michael J Bonidie; Steven D Abramowitch; Pamela A Moalli
Journal:  Am J Obstet Gynecol       Date:  2016-04-16       Impact factor: 8.661

8.  Textile properties of synthetic prolapse mesh in response to uniaxial loading.

Authors:  William R Barone; Pamela A Moalli; Steven D Abramowitch
Journal:  Am J Obstet Gynecol       Date:  2016-03-18       Impact factor: 8.661

Review 9.  Exploring the basic science of prolapse meshes.

Authors:  Rui Liang; Katrina Knight; Steve Abramowitch; Pamela A Moalli
Journal:  Curr Opin Obstet Gynecol       Date:  2016-10       Impact factor: 1.927

10.  A Novel Operative Procedure for Pelvic Organ Prolapse Utilizing a MRI-Visible Mesh Implant: Safety and Outcome of Modified Laparoscopic Bilateral Sacropexy.

Authors:  Ralf Joukhadar; Gabriele Meyberg-Solomayer; Amr Hamza; Julia Radosa; Werner Bader; Dimitri Barski; Fakher Ismaeel; Guenther Schneider; Erich Solomayer; Sascha Baum
Journal:  Biomed Res Int       Date:  2015-04-19       Impact factor: 3.411

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