Literature DB >> 23610370

Mendel: the Swiss army knife of genetic analysis programs.

Kenneth Lange1, Jeanette C Papp, Janet S Sinsheimer, Ram Sripracha, Hua Zhou, Eric M Sobel.   

Abstract

UNLABELLED: Mendel is one of the few statistical genetics packages that provide a full spectrum of gene mapping methods, ranging from parametric linkage in large pedigrees to genome-wide association with rare variants. Our latest additions to Mendel anticipate and respond to the needs of the genetics community. Compared with earlier versions, Mendel is faster and easier to use and has a wider range of applications. Supported platforms include Linux, MacOS and Windows. AVAILABILITY: Free from www.genetics.ucla.edu/software/mendel.

Mesh:

Year:  2013        PMID: 23610370      PMCID: PMC3673222          DOI: 10.1093/bioinformatics/btt187

Source DB:  PubMed          Journal:  Bioinformatics        ISSN: 1367-4803            Impact factor:   6.937


  22 in total

1.  Association screening of common and rare genetic variants by penalized regression.

Authors:  Hua Zhou; Mary E Sehl; Janet S Sinsheimer; Kenneth Lange
Journal:  Bioinformatics       Date:  2010-08-06       Impact factor: 6.937

2.  The pedigree trimming problem.

Authors:  Kenneth Lange; Janet S Sinsheimer
Journal:  Hum Hered       Date:  2004       Impact factor: 0.444

3.  Estimating ethnic admixture from pedigree data.

Authors:  Janet S Sinsheimer; Christopher L Plaisier; Adriana Huertas-Vazquez; Carlos Aguilar-Salinas; Teresa Tusie-Luna; Päivi Pajukanta; Kenneth Lange
Journal:  Am J Hum Genet       Date:  2008-03       Impact factor: 11.025

4.  A heterozygote-homozygote test of Hardy-Weinberg equilibrium.

Authors:  Jin J Zhou; Kenneth Lange; Jeanette C Papp; Janet S Sinsheimer
Journal:  Eur J Hum Genet       Date:  2009-04-15       Impact factor: 4.246

5.  Genome-wide association analysis by lasso penalized logistic regression.

Authors:  Tong Tong Wu; Yi Fang Chen; Trevor Hastie; Eric Sobel; Kenneth Lange
Journal:  Bioinformatics       Date:  2009-01-28       Impact factor: 6.937

Review 6.  Family-based designs for genome-wide association studies.

Authors:  Jurg Ott; Yoichiro Kamatani; Mark Lathrop
Journal:  Nat Rev Genet       Date:  2011-06-01       Impact factor: 53.242

Review 7.  Genome simulation approaches for synthesizing in silico datasets for human genomics.

Authors:  Marylyn D Ritchie; William S Bush
Journal:  Adv Genet       Date:  2010       Impact factor: 1.944

8.  Penalized regression for genome-wide association screening of sequence data.

Authors:  H Zhou; D H Alexander; M E Sehl; J S Sinsheimer; E M Sobel; K Lange
Journal:  Pac Symp Biocomput       Date:  2011

9.  Linkage analysis without defined pedigrees.

Authors:  Aaron G Day-Williams; John Blangero; Thomas D Dyer; Kenneth Lange; Eric M Sobel
Journal:  Genet Epidemiol       Date:  2011-04-04       Impact factor: 2.135

10.  Modeling maternal-offspring gene-gene interactions: the extended-MFG test.

Authors:  Erica J Childs; Christina G S Palmer; Kenneth Lange; Janet S Sinsheimer
Journal:  Genet Epidemiol       Date:  2010-07       Impact factor: 2.135

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  63 in total

1.  Family-specific aggregation of lipid GWAS variants confers the susceptibility to familial hypercholesterolemia in a large Austrian family.

Authors:  Elina Nikkola; Arthur Ko; Marcus Alvarez; Rita M Cantor; Kristina Garske; Elliot Kim; Stephanie Gee; Alejandra Rodriguez; Reinhard Muxel; Niina Matikainen; Sanni Söderlund; Mahdi M Motazacker; Jan Borén; Claudia Lamina; Florian Kronenberg; Wolfgang J Schneider; Aarno Palotie; Markku Laakso; Marja-Riitta Taskinen; Päivi Pajukanta
Journal:  Atherosclerosis       Date:  2017-07-22       Impact factor: 5.162

2.  A FAST ALGORITHM FOR DETECTING GENE-GENE INTERACTIONS IN GENOME-WIDE ASSOCIATION STUDIES.

Authors:  Jiahan Li; Wei Zhong; Runze Li; Rongling Wu
Journal:  Ann Appl Stat       Date:  2014       Impact factor: 2.083

Review 3.  Bias Correction Methods Explain Much of the Variation Seen in Breast Cancer Risks of BRCA1/2 Mutation Carriers.

Authors:  Janet R Vos; Li Hsu; Richard M Brohet; Marian J E Mourits; Jakob de Vries; Kathleen E Malone; Jan C Oosterwijk; Geertruida H de Bock
Journal:  J Clin Oncol       Date:  2015-07-06       Impact factor: 44.544

4.  Ordered multinomial regression for genetic association analysis of ordinal phenotypes at Biobank scale.

Authors:  Christopher A German; Janet S Sinsheimer; Yann C Klimentidis; Hua Zhou; Jin J Zhou
Journal:  Genet Epidemiol       Date:  2019-12-26       Impact factor: 2.135

5.  Non-parametric estimation of survival in age-dependent genetic disease and application to the transthyretin-related hereditary amyloidosis.

Authors:  Flora Alarcon; Violaine Planté-Bordeneuve; Malin Olsson; Grégory Nuel
Journal:  PLoS One       Date:  2018-09-25       Impact factor: 3.240

6.  Iterative hard thresholding in genome-wide association studies: Generalized linear models, prior weights, and double sparsity.

Authors:  Benjamin B Chu; Kevin L Keys; Christopher A German; Hua Zhou; Jin J Zhou; Eric M Sobel; Janet S Sinsheimer; Kenneth Lange
Journal:  Gigascience       Date:  2020-06-01       Impact factor: 6.524

7.  Interactions of early adversity with stress-related gene polymorphisms impact regional brain structure in females.

Authors:  Arpana Gupta; Jennifer Labus; Lisa A Kilpatrick; Mariam Bonyadi; Cody Ashe-McNalley; Nuwanthi Heendeniya; Sylvie Bradesi; Lin Chang; Emeran A Mayer
Journal:  Brain Struct Funct       Date:  2015-01-30       Impact factor: 3.270

8.  Next Generation Statistical Genetics: Modeling, Penalization, and Optimization in High-Dimensional Data.

Authors:  Kenneth Lange; Jeanette C Papp; Janet S Sinsheimer; Eric M Sobel
Journal:  Annu Rev Stat Appl       Date:  2014-01-01       Impact factor: 5.810

Review 9.  Fine-mapping QTLs in advanced intercross lines and other outbred populations.

Authors:  Natalia M Gonzales; Abraham A Palmer
Journal:  Mamm Genome       Date:  2014-06-07       Impact factor: 2.957

10.  Fast Genome-Wide QTL Association Mapping on Pedigree and Population Data.

Authors:  Hua Zhou; John Blangero; Thomas D Dyer; Kei-Hang K Chan; Kenneth Lange; Eric M Sobel
Journal:  Genet Epidemiol       Date:  2016-12-12       Impact factor: 2.135

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