Literature DB >> 23609796

Set them free: F-box protein exchange by Cand1.

Karin Flick1, Peter Kaiser.   

Abstract

Cand1 (Cullin-associated and neddylation-dissociated protein 1) has long been known as a regulator of SCF ubiquitin ligases, but details remained puzzling due to conflicting results from in vitro and in vivo experiments. Three recent reports, one in Cell and two in Nature Communications, propose Cand1 as a protein exchange factor with interesting mechanism that reconciles Cand1 genetics and biochemistry.

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Year:  2013        PMID： 23609796      PMCID： PMC3698631          DOI： 10.1038/cr.2013.55

Source DB:  PubMed          Journal:  Cell Res        ISSN： 1001-0602            Impact factor:   25.617


  11 in total

1.  CAND1 binds to unneddylated CUL1 and regulates the formation of SCF ubiquitin E3 ligase complex.

Authors:  Jianyu Zheng; Xiaoming Yang; Jennifer M Harrell; Sophia Ryzhikov; Eun Hee Shim; Karin Lykke-Andersen; Ning Wei; Hong Sun; Ryuji Kobayashi; Hui Zhang
Journal:  Mol Cell       Date:  2002-12       Impact factor: 17.970

2.  The molecular basis of CRL4DDB2/CSA ubiquitin ligase architecture, targeting, and activation.

Authors:  Eric S Fischer; Andrea Scrima; Kerstin Böhm; Syota Matsumoto; Gondichatnahalli M Lingaraju; Mahamadou Faty; Takeshi Yasuda; Simone Cavadini; Mitsuo Wakasugi; Fumio Hanaoka; Shigenori Iwai; Heinz Gut; Kaoru Sugasawa; Nicolas H Thomä
Journal:  Cell       Date:  2011-11-23       Impact factor: 41.582

Review 3.  The ubiquitin system, an immense realm.

Authors:  Alexander Varshavsky
Journal:  Annu Rev Biochem       Date:  2012       Impact factor: 23.643

Review 4.  Function and regulation of cullin-RING ubiquitin ligases.

Authors:  Matthew D Petroski; Raymond J Deshaies
Journal:  Nat Rev Mol Cell Biol       Date:  2005-01       Impact factor: 94.444

5.  NEDD8 modification of CUL1 dissociates p120(CAND1), an inhibitor of CUL1-SKP1 binding and SCF ligases.

Authors:  Jidong Liu; Manabu Furukawa; Tomohiro Matsumoto; Yue Xiong
Journal:  Mol Cell       Date:  2002-12       Impact factor: 17.970

Review 6.  Structural regulation of cullin-RING ubiquitin ligase complexes.

Authors:  David M Duda; Daniel C Scott; Matthew F Calabrese; Erik S Zimmerman; Ning Zheng; Brenda A Schulman
Journal:  Curr Opin Struct Biol       Date:  2011-02-01       Impact factor: 6.809

7.  CSN- and CAND1-dependent remodelling of the budding yeast SCF complex.

Authors:  Aleksandra Zemla; Yann Thomas; Sylwia Kedziora; Axel Knebel; Nicola T Wood; Gwenaël Rabut; Thimo Kurz
Journal:  Nat Commun       Date:  2013       Impact factor: 14.919

8.  Cullin-RING ubiquitin ligases: global regulation and activation cycles.

Authors:  Dimple R Bosu; Edward T Kipreos
Journal:  Cell Div       Date:  2008-02-18       Impact factor: 5.130

9.  CAND1 controls in vivo dynamics of the cullin 1-RING ubiquitin ligase repertoire.

Authors:  Shuangding Wu; Wenhong Zhu; Tina Nhan; Julia I Toth; Matthew D Petroski; Dieter A Wolf
Journal:  Nat Commun       Date:  2013       Impact factor: 14.919

10.  Structural basis for a reciprocal regulation between SCF and CSN.

Authors:  Radoslav I Enchev; Daniel C Scott; Paula C A da Fonseca; Anne Schreiber; Julie K Monda; Brenda A Schulman; Matthias Peter; Edward P Morris
Journal:  Cell Rep       Date:  2012-09-06       Impact factor: 9.423
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  6 in total

1.  Functional Genomic Landscape of Human Breast Cancer Drivers, Vulnerabilities, and Resistance.

Authors:  Richard Marcotte; Azin Sayad; Kevin R Brown; Felix Sanchez-Garcia; Jüri Reimand; Maliha Haider; Carl Virtanen; James E Bradner; Gary D Bader; Gordon B Mills; Dana Pe'er; Jason Moffat; Benjamin G Neel
Journal:  Cell       Date:  2016-01-14       Impact factor: 41.582

2.  Skp1 Independent Function of Cdc53/Cul1 in F-box Protein Homeostasis.

Authors:  Radhika Mathur; James L Yen; Peter Kaiser
Journal:  PLoS Genet       Date:  2015-12-10       Impact factor: 5.917

Review 3.  An Update on Jacalin-Like Lectins and Their Role in Plant Defense.

Authors:  Lara Esch; Ulrich Schaffrath
Journal:  Int J Mol Sci       Date:  2017-07-22       Impact factor: 5.923

4.  Small molecule perturbation of the CAND1-Cullin1-ubiquitin cycle stabilizes p53 and triggers Epstein-Barr virus reactivation.

Authors:  Nadezhda Tikhmyanova; Steve Tutton; Kayla A Martin; Fang Lu; Andrew V Kossenkov; Nicholas Paparoidamis; Shannon Kenney; Joseph M Salvino; Paul M Lieberman
Journal:  PLoS Pathog       Date:  2017-07-17       Impact factor: 6.823

Review 5.  How Influenza A Virus NS1 Deals with the Ubiquitin System to Evade Innate Immunity.

Authors:  Laurie-Anne Lamotte; Lionel Tafforeau
Journal:  Viruses       Date:  2021-11-19       Impact factor: 5.048

6.  Phospholipidation of nuclear proteins by the human papillomavirus E6 oncoprotein: implication in carcinogenesis.

Authors:  Benjamin Marx; Martin Hufbauer; Paola Zigrino; Slawomir Majewski; Birgid Markiefka; Timo Sachsenheimer; Britta Brügger; Baki Akgül
Journal:  Oncotarget       Date:  2018-09-25
  6 in total

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