Literature DB >> 23603676

Repression of antibiotic downregulator WblA by AdpA in Streptomyces coelicolor.

Han-Na Lee1, Jin-Su Kim, Pil Kim, Heung-Shick Lee, Eung-Soo Kim.   

Abstract

The upstream region of antibiotic downregulatory wblA in Streptomyces coelicolor was found to contain AdpA binding motifs. A key morphological regulator, AdpA was shown to specifically bind these motifs by electrophoretic mobility shift assay. An adpA disruption mutant exhibited increased wblA transcription, suggesting that AdpA negatively regulates wblA transcription in S. coelicolor.

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Year:  2013        PMID： 23603676      PMCID： PMC3697564          DOI： 10.1128/AEM.00546-13

Source DB:  PubMed          Journal:  Appl Environ Microbiol        ISSN： 0099-2240            Impact factor:   4.792


  34 in total

Review 1.  Streptomyces morphogenetics: dissecting differentiation in a filamentous bacterium.

Authors:  Klas Flärdh; Mark J Buttner
Journal:  Nat Rev Microbiol       Date:  2009-01       Impact factor: 60.633

2.  Isolation and genetic manipulation of the antibiotic down-regulatory gene, wblA ortholog for doxorubicin-producing Streptomyces strain improvement.

Authors:  Jun-Hee Noh; Seon-Hye Kim; Han-Na Lee; Sang Yup Lee; Eung-Soo Kim
Journal:  Appl Microbiol Biotechnol       Date:  2009-12-18       Impact factor: 4.813

3.  The SigF regulon in Mycobacterium smegmatis reveals roles in adaptation to stationary phase, heat, and oxidative stress.

Authors:  Anja Hümpel; Susanne Gebhard; Gregory M Cook; Michael Berney
Journal:  J Bacteriol       Date:  2010-03-16       Impact factor: 3.490

4.  Putative TetR family transcriptional regulator SCO1712 encodes an antibiotic downregulator in Streptomyces coelicolor.

Authors:  Han-Na Lee; Jianqiang Huang; Jong-Hyuk Im; Seon-Hye Kim; Jun-Hee Noh; Stanley N Cohen; Eung-Soo Kim
Journal:  Appl Environ Microbiol       Date:  2010-02-26       Impact factor: 4.792

Review 5.  Gamma-butyrolactones: Streptomyces signalling molecules regulating antibiotic production and differentiation.

Authors:  Eriko Takano
Journal:  Curr Opin Microbiol       Date:  2006-05-03       Impact factor: 7.934

Review 6.  Signals and regulators that govern Streptomyces development.

Authors:  Joseph R McCormick; Klas Flärdh
Journal:  FEMS Microbiol Rev       Date:  2011-12-02       Impact factor: 16.408

7.  DNA microarray analysis of global gene regulation by A-factor in Streptomyces griseus.

Authors:  Hirofumi Hara; Yasuo Ohnishi; Sueharu Horinouchi
Journal:  Microbiology       Date:  2009-04-23       Impact factor: 2.777

8.  Dynamic changes in the extracellular proteome caused by absence of a pleiotropic regulator AdpA in Streptomyces griseus.

Authors:  Genki Akanuma; Hirofumi Hara; Yasuo Ohnishi; Sueharu Horinouchi
Journal:  Mol Microbiol       Date:  2009-08-04       Impact factor: 3.501

9.  Interspecies DNA microarray analysis identifies WblA as a pleiotropic down-regulator of antibiotic biosynthesis in Streptomyces.

Authors:  Seung-Hoon Kang; Jianqiang Huang; Han-Na Lee; Yoon-Ah Hur; Stanley N Cohen; Eung-Soo Kim
Journal:  J Bacteriol       Date:  2007-04-06       Impact factor: 3.490

10.  Negative role of wblA in response to oxidative stress in Streptomyces coelicolor.

Authors:  Jin-Su Kim; Han-Na Lee; Pil Kim; Heung-Shick Lee; Eung-Soo Kim
Journal:  J Microbiol Biotechnol       Date:  2012-06       Impact factor: 2.351
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  11 in total

1.  Transcriptional regulation of the daptomycin gene cluster in Streptomyces roseosporus by an autoregulator, AtrA.

Authors:  Xu-Ming Mao; Shuai Luo; Ri-Cheng Zhou; Feng Wang; Pin Yu; Ning Sun; Xiao-Xia Chen; Yi Tang; Yong-Quan Li
Journal:  J Biol Chem       Date:  2015-02-03       Impact factor: 5.157

2.  WblAch, a pivotal activator of natamycin biosynthesis and morphological differentiation in Streptomyces chattanoogensis L10, is positively regulated by AdpAch.

Authors:  Pin Yu; Shui-Ping Liu; Qing-Ting Bu; Zhen-Xing Zhou; Zhen-Hong Zhu; Fang-Liang Huang; Yong-Quan Li
Journal:  Appl Environ Microbiol       Date:  2014-08-29       Impact factor: 4.792

3.  Characterization of representative rpoB gene mutations leading to a significant change in toyocamycin production of Streptomyces diastatochromogenes 1628.

Authors:  Zheng Ma; Shuai Luo; Xianhao Xu; Andreas Bechthold; Xiaoping Yu
Journal:  J Ind Microbiol Biotechnol       Date:  2016-01-20       Impact factor: 3.346

4.  Pleiotropic regulatory genes bldA, adpA and absB are implicated in production of phosphoglycolipid antibiotic moenomycin.

Authors:  Roman Makitrynskyy; Bohdan Ostash; Olga Tsypik; Yuriy Rebets; Emma Doud; Timothy Meredith; Andriy Luzhetskyy; Andreas Bechthold; Suzanne Walker; Victor Fedorenko
Journal:  Open Biol       Date:  2013-10-23       Impact factor: 6.411

5.  In conditions of over-expression, WblI, a WhiB-like transcriptional regulator, has a positive impact on the weak antibiotic production of Streptomyces lividans TK24.

Authors:  Lan Yan; Qizhong Zhang; Marie-Joelle Virolle; Delin Xu
Journal:  PLoS One       Date:  2017-03-30       Impact factor: 3.240

6.  SbbR/SbbA, an Important ArpA/AfsA-Like System, Regulates Milbemycin Production in Streptomyces bingchenggensis.

Authors:  Hairong He; Lan Ye; Chuang Li; Haiyan Wang; Xiaowei Guo; Xiangjing Wang; Yanyan Zhang; Wensheng Xiang
Journal:  Front Microbiol       Date:  2018-05-23       Impact factor: 5.640

Review 7.  WblA, a global regulator of antibiotic biosynthesis in Streptomyces.

Authors:  Hee-Ju Nah; Jihee Park; Sisun Choi; Eung-Soo Kim
Journal:  J Ind Microbiol Biotechnol       Date:  2021-06-04       Impact factor: 4.258

8.  Identified members of the Streptomyces lividans AdpA regulon involved in differentiation and secondary metabolism.

Authors:  Aurélie Guyet; Nadia Benaroudj; Caroline Proux; Myriam Gominet; Jean-Yves Coppée; Philippe Mazodier
Journal:  BMC Microbiol       Date:  2014-04-03       Impact factor: 3.605

9.  Genome-Wide Chromatin Immunoprecipitation Sequencing Analysis Shows that WhiB Is a Transcription Factor That Cocontrols Its Regulon with WhiA To Initiate Developmental Cell Division in Streptomyces.

Authors:  Matthew J Bush; Govind Chandra; Maureen J Bibb; Kim C Findlay; Mark J Buttner
Journal:  mBio       Date:  2016-04-19       Impact factor: 7.867

10.  Rational engineering of Streptomyces albus J1074 for the overexpression of secondary metabolite gene clusters.

Authors:  Dimitris Kallifidas; Guangde Jiang; Yousong Ding; Hendrik Luesch
Journal:  Microb Cell Fact       Date:  2018-02-17       Impact factor: 5.328
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