| Literature DB >> 23584895 |
Laura K Moore1, Edward K Chow2, Eiji Osawa3, J Michael Bishop4, Dean Ho5.
Abstract
Self-assembled nanodiamond-lipid hybrid particles (NDLPs) harness the potent interaction between the nanodiamond (ND)-surface and small molecules, while providing a mechanism for cell-targeted imaging and therapy of triple negative breast cancers. Epidermal growth factor receptor-targeted NDLPs are highly biocompatible particles that provide cell-specific imaging, promote tumor retention of ND-complexes, prevent epirubicin toxicities and mediate regression of triple negative breast cancers.Entities:
Keywords: cancer; drug delivery; hybrid nanomaterials; nanodiamond; nanomedicine
Mesh:
Substances:
Year: 2013 PMID: 23584895 PMCID: PMC3872062 DOI: 10.1002/adma.201300343
Source DB: PubMed Journal: Adv Mater ISSN: 0935-9648 Impact factor: 30.849