| Literature DB >> 23584094 |
Annick Harel-Bellan1, Maya Ameyar Zazoua, Christophe Rachez, Christian Muchardt, Eric Batsché.
Abstract
Whereas in yeast the function and mode of action of nuclear RNAi are well documented, mammalian nuclear RNAi is a matter of debates. Several papers support a role for nuclear Argonaute in alternative splicing. However, the molecular mechanism remains elusive. Here, we discuss the human nuclear RNAi mechanism in light of what is known of the yeast process.Entities:
Keywords: AGO; AS lincRNA; mammals; nuclear RNAi; splicing
Mesh:
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Year: 2013 PMID: 23584094 PMCID: PMC4042589 DOI: 10.4161/trns.24582
Source DB: PubMed Journal: Transcription ISSN: 2154-1272