| Literature DB >> 15979194 |
Robert A Martienssen1, Mikel Zaratiegui, Derek B Goto.
Abstract
Fission yeast is a useful model for RNA interference because it has single-copy genes for components of the RNAi pathway such as argonaute, dicer and RNA-dependent RNA polymerase (RdRP). Functions for RNAi revealed in S. pombe, such as heterochromatic silencing and chromosome segregation, are likely to be ancient because they are shared with some other eukaryotes. The underlying mechanisms are being rapidly unraveled.Entities:
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Year: 2005 PMID： 15979194 DOI： 10.1016/j.tig.2005.06.005
Source DB: PubMed Journal: Trends Genet ISSN： 0168-9525 Impact factor: 11.639