| Literature DB >> 23583893 |
Abstract
Poxvirus expression vectors were described in 1982 and quickly became widely used for vaccine development as well as research in numerous fields. Advantages of the vectors include simple construction, ability to accommodate large amounts of foreign DNA and high expression levels. Numerous poxvirus-based veterinary vaccines are currently in use and many others are in human clinical trials. The early reports of poxvirus vectors paved the way for and stimulated the development of other viral vectors and recombinant DNA vaccines. Published by Elsevier Ltd.Entities:
Keywords: DNA cloning; Recombinant DNA; Recombinant vaccines; Vaccine vectors; Vaccinia virus
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Year: 2013 PMID: 23583893 PMCID: PMC3755097 DOI: 10.1016/j.vaccine.2013.03.042
Source DB: PubMed Journal: Vaccine ISSN: 0264-410X Impact factor: 3.641