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Literature DB >> 23579660

Genetics: a gene of rare effect.

Stephen S Hall.

Abstract

Mesh：

Substances：

Year: 2013 PMID： 23579660 DOI： 10.1038/496152a

Source DB: PubMed Journal: Nature ISSN： 0028-0836 Impact factor: 49.962

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14 in total

1. Sequence variations in PCSK9, low LDL, and protection against coronary heart disease.

Authors: Jonathan C Cohen; Eric Boerwinkle; Thomas H Mosley; Helen H Hobbs
Journal: N Engl J Med Date: 2006-03-23 Impact factor: 91.245

2. Implication of the proprotein convertase NARC-1/PCSK9 in the development of the nervous system.

Authors: Steve Poirier; Annik Prat; Edwige Marcinkiewicz; Joanne Paquin; Babykumari P Chitramuthu; David Baranowski; Benoit Cadieux; Hugh P J Bennett; Nabil G Seidah
Journal: J Neurochem Date: 2006-08 Impact factor: 5.372

3. Efficacy, safety, and tolerability of a monoclonal antibody to proprotein convertase subtilisin/kexin type 9 as monotherapy in patients with hypercholesterolaemia (MENDEL): a randomised, double-blind, placebo-controlled, phase 2 study.

Authors: Michael J Koren; Rob Scott; Jae B Kim; Beat Knusel; Thomas Liu; Lei Lei; Michael Bolognese; Scott M Wasserman
Journal: Lancet Date: 2012-11-06 Impact factor: 79.321

4. Molecular characterization of loss-of-function mutations in PCSK9 and identification of a compound heterozygote.

Authors: Zhenze Zhao; Yetsa Tuakli-Wosornu; Thomas A Lagace; Lisa Kinch; Nicholas V Grishin; Jay D Horton; Jonathan C Cohen; Helen H Hobbs
Journal: Am J Hum Genet Date: 2006-07-18 Impact factor: 11.025

5. Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes.

Authors: Jay D Horton; Nila A Shah; Janet A Warrington; Norma N Anderson; Sahng Wook Park; Michael S Brown; Joseph L Goldstein
Journal: Proc Natl Acad Sci U S A Date: 2003-09-25 Impact factor: 11.205

6. Mutations in PCSK9 cause autosomal dominant hypercholesterolemia.

Authors: Marianne Abifadel; Mathilde Varret; Jean-Pierre Rabès; Delphine Allard; Khadija Ouguerram; Martine Devillers; Corinne Cruaud; Suzanne Benjannet; Louise Wickham; Danièle Erlich; Aurélie Derré; Ludovic Villéger; Michel Farnier; Isabel Beucler; Eric Bruckert; Jean Chambaz; Bernard Chanu; Jean-Michel Lecerf; Gerald Luc; Philippe Moulin; Jean Weissenbach; Annick Prat; Michel Krempf; Claudine Junien; Nabil G Seidah; Catherine Boileau
Journal: Nat Genet Date: 2003-06 Impact factor: 38.330

7. Adenoviral-mediated expression of Pcsk9 in mice results in a low-density lipoprotein receptor knockout phenotype.

Authors: Kara N Maxwell; Jan L Breslow
Journal: Proc Natl Acad Sci U S A Date: 2004-04-26 Impact factor: 11.205

8. Novel putative SREBP and LXR target genes identified by microarray analysis in liver of cholesterol-fed mice.

Authors: Kara N Maxwell; Raymond E Soccio; Elizabeth M Duncan; Ephraim Sehayek; Jan L Breslow
Journal: J Lipid Res Date: 2003-08-01 Impact factor: 5.922

9. Atorvastatin with or without an antibody to PCSK9 in primary hypercholesterolemia.

Authors: Eli M Roth; James M McKenney; Corinne Hanotin; Gaelle Asset; Evan A Stein
Journal: N Engl J Med Date: 2012-10-31 Impact factor: 91.245

10. PCSK9: a convertase that coordinates LDL catabolism.

Authors: Jay D Horton; Jonathan C Cohen; Helen H Hobbs
Journal: J Lipid Res Date: 2008-11-19 Impact factor: 5.922

13 in total

Review 1. The past 10 years-new hormones, new functions, new endocrine organs.

Authors: Roger Bouillon; Daniel J Drucker; Ele Ferrannini; Steven Grinspoon; Clifford J Rosen; Paul Zimmet
Journal: Nat Rev Endocrinol Date: 2015-09-01 Impact factor: 43.330

Review 2. Genetics of extreme human longevity to guide drug discovery for healthy ageing.

Authors: Zhengdong D Zhang; Sofiya Milman; Jhih-Rong Lin; Shayne Wierbowski; Haiyuan Yu; Nir Barzilai; Vera Gorbunova; Warren C Ladiges; Laura J Niedernhofer; Yousin Suh; Paul D Robbins; Jan Vijg
Journal: Nat Metab Date: 2020-07-27

Review 3. Individualized medicine from prewomb to tomb.

Authors: Eric J Topol
Journal: Cell Date: 2014-03-27 Impact factor: 41.582

4. Praluent (Alirocumab): First PCSK9 Inhibitor Approved by the FDA for Hypercholesterolemia.

Authors: Lisa A Raedler
Journal: Am Health Drug Benefits Date: 2016-03

5. Accelerating Precision Drug Development and Drug Repurposing by Leveraging Human Genetics.

Authors: Jill M Pulley; Jana K Shirey-Rice; Robert R Lavieri; Rebecca N Jerome; Nicole M Zaleski; David M Aronoff; Lisa Bastarache; Xinnan Niu; Kenneth J Holroyd; Dan M Roden; Eric P Skaar; Colleen M Niswender; Lawrence J Marnett; Craig W Lindsley; Leeland B Ekstrom; Alan R Bentley; Gordon R Bernard; Charles C Hong; Joshua C Denny
Journal: Assay Drug Dev Technol Date: 2017-04-05 Impact factor: 1.738

Review 6. [Introduction of PCSK9 inhibitors : New perspectives in treatment and practical implementation].

Authors: G Klose
Journal: Herz Date: 2016-06 Impact factor: 1.443

7. Prognostic Implications of Long-Chain Acylcarnitines in Heart Failure and Reversibility With Mechanical Circulatory Support.

Authors: Tariq Ahmad; Jacob P Kelly; Robert W McGarrah; Anne S Hellkamp; Mona Fiuzat; Jeffrey M Testani; Teresa S Wang; Amanda Verma; Marc D Samsky; Mark P Donahue; Olga R Ilkayeva; Dawn E Bowles; Chetan B Patel; Carmelo A Milano; Joseph G Rogers; G Michael Felker; Christopher M O'Connor; Svati H Shah; William E Kraus
Journal: J Am Coll Cardiol Date: 2016-01-26 Impact factor: 24.094

8. The dual behavior of PCSK9 in the regulation of apoptosis is crucial in Alzheimer's disease progression (Review).

Authors: Qi Wu; Zhi-Han Tang; Juan Peng; Ling Liao; Li-Hong Pan; Chun-Yan Wu; Zhi-Sheng Jiang; Gui-Xue Wang; Lu-Shan Liu
Journal: Biomed Rep Date: 2013-12-30

9. Whole-Genome Sequencing of Pharmacogenetic Drug Response in Racially Diverse Children with Asthma.

Authors: Angel C Y Mak; Marquitta J White; Walter L Eckalbar; Zachary A Szpiech; Sam S Oh; Maria Pino-Yanes; Donglei Hu; Pagé Goddard; Scott Huntsman; Joshua Galanter; Ann Chen Wu; Blanca E Himes; Soren Germer; Julia M Vogel; Karen L Bunting; Celeste Eng; Sandra Salazar; Kevin L Keys; Jennifer Liberto; Thomas J Nuckton; Thomas A Nguyen; Dara G Torgerson; Pui-Yan Kwok; Albert M Levin; Juan C Celedón; Erick Forno; Hakon Hakonarson; Patrick M Sleiman; Amber Dahlin; Kelan G Tantisira; Scott T Weiss; Denise Serebrisky; Emerita Brigino-Buenaventura; Harold J Farber; Kelley Meade; Michael A Lenoir; Pedro C Avila; Saunak Sen; Shannon M Thyne; William Rodriguez-Cintron; Cheryl A Winkler; Andrés Moreno-Estrada; Karla Sandoval; Jose R Rodriguez-Santana; Rajesh Kumar; L Keoki Williams; Nadav Ahituv; Elad Ziv; Max A Seibold; Robert B Darnell; Noah Zaitlen; Ryan D Hernandez; Esteban G Burchard
Journal: Am J Respir Crit Care Med Date: 2018-06-15 Impact factor: 30.528

Review 10. Human Knockout Carriers: Dead, Diseased, Healthy, or Improved?

Authors: Vagheesh M Narasimhan; Yali Xue; Chris Tyler-Smith
Journal: Trends Mol Med Date: 2016-03-14 Impact factor: 11.951