OBJECTIVE: To establish the wound healing activity of aqueous and ethanolic extract of roots of Ficus racemosa (F. racemosa). METHODS: Two models were performed to evaluate the wound healing activity i.e. incision and excision models. In incision model the parameter which was carried out was breaking strength of wounded skin. In excision model percentage wound contraction and period of epithelialization were established for both the extracts. Reference standard drug was povidone iodine ointment for comparison with other groups. RESULTS: From the observation in both two models, aqueous extract of F. racemosa was found to have greater wound healing activity in terms of breaking strength in incision model and percentage wound contraction, period of epithelialization in excision model than that of other groups. CONCLUSIONS: In conclusion, our findings suggest that aqueous extract of F. racemosa possesses better wound healing ability than the ethanolic extract.
OBJECTIVE: To establish the wound healing activity of aqueous and ethanolic extract of roots of Ficus racemosa (F. racemosa). METHODS: Two models were performed to evaluate the wound healing activity i.e. incision and excision models. In incision model the parameter which was carried out was breaking strength of wounded skin. In excision model percentage wound contraction and period of epithelialization were established for both the extracts. Reference standard drug was povidone iodine ointment for comparison with other groups. RESULTS: From the observation in both two models, aqueous extract of F. racemosa was found to have greater wound healing activity in terms of breaking strength in incision model and percentage wound contraction, period of epithelialization in excision model than that of other groups. CONCLUSIONS: In conclusion, our findings suggest that aqueous extract of F. racemosa possesses better wound healing ability than the ethanolic extract.
Authors: Dnyaneshwar D Kokane; Rahul Y More; Mandar B Kale; Minakshi N Nehete; Prachi C Mehendale; Chhaya H Gadgoli Journal: J Ethnopharmacol Date: 2009-05-03 Impact factor: 4.360
Authors: Zili Zhai; Devon M Haney; Lankun Wu; Avery K Solco; Patricia A Murphy; Eve S Wurtele; Marian L Kohut; Joan E Cunnick Journal: Phytomedicine Date: 2009-03-20 Impact factor: 5.340