| Literature DB >> 23568508 |
Anja Kastl1, Sandra Dieckmann, Kathrin Wähler, Timo Völker, Lena Kastl, Anna Lena Merkel, Adina Vultur, Batool Shannan, Klaus Harms, Matthias Ocker, Wolfgang J Parak, Meenhard Herlyn, Eric Meggers.
Abstract
Shedding light on the matter: Rhenium(I) indolato complexes with highly potent visible-light-triggered antiproliferative activity (complex 1: EC50 light=0.1 μM vs EC50 dark=100 μM) in 2D- and 3D-organized cancer cells are reported and can be traced back to an efficient generation of singlet oxygen, causing rapid morphological changes and an induction of apoptosis.Entities:
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Year: 2013 PMID: 23568508 PMCID: PMC3665699 DOI: 10.1002/cmdc.201300060
Source DB: PubMed Journal: ChemMedChem ISSN: 1860-7179 Impact factor: 3.466