Literature DB >> 23557711

An analysis of FMA using structural self-bisimilarity.

Lingyun Luo1, José L V Mejino, Guo-Qiang Zhang.   

Abstract

As ontologies are mostly manually created, they tend to contain errors and inconsistencies. In this paper, we present an automated computational method to audit symmetric concepts in ontologies by leveraging self-bisimilarity and linguistic structure in the concept names. Two concepts A and B are symmetric if concept B can be obtained from concept A by replacing a single modifier such as "left" with its symmetric modifier such as "right." All possible local structural types for symmetric concept pairs are enumerated according to their local subsumption hierarchy, and the pairs are further classified into Non-Matches and Matches. To test the feasibility and validate the benefits of this method, we computed all the symmetric modifier pairs in the Foundational Model of Anatomy (FMA) and selected six of them for experimentation. 9893 Non-Matches and 221 abnormal Matches with potential errors were discovered by our algorithm. Manual evaluation by FMA domain experts on 176 selected Non-Matches and all the 221 abnormal Matches found 102 missing concepts and 40 misaligned concepts. Corrections for them have currently been implemented in the latest version of FMA. Our result demonstrates that self-bisimilarity can be a valuable method for ontology quality assurance, particularly in uncovering missing concepts and misaligned concepts. Our approach is computationally scalable and can be applied to other ontologies that are rich in symmetric concepts.
Copyright © 2013 Elsevier Inc. All rights reserved.

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Year:  2013        PMID: 23557711      PMCID: PMC3690136          DOI: 10.1016/j.jbi.2013.03.005

Source DB:  PubMed          Journal:  J Biomed Inform        ISSN: 1532-0464            Impact factor:   6.317


  19 in total

1.  Assessing the consistency of a biomedical terminology through lexical knowledge.

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2.  Evaluation of the UMLS as a terminology and knowledge resource for biomedical informatics.

Authors:  Olivier Bodenreider; Joyce A Mitchell; Alexa T McCray
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3.  Non-lexical approaches to identifying associative relations in the gene ontology.

Authors:  Olivier Bodenreider; Marc Aubry; Anita Burgun
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4.  Structural methodologies for auditing SNOMED.

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Journal:  J Biomed Inform       Date:  2006-12-24       Impact factor: 6.317

5.  Auditing as part of the terminology design life cycle.

Authors:  Hua Min; Yehoshua Perl; Yan Chen; Michael Halper; James Geller; Yue Wang
Journal:  J Am Med Inform Assoc       Date:  2006-08-23       Impact factor: 4.497

Review 6.  A review of auditing methods applied to the content of controlled biomedical terminologies.

Authors:  Xinxin Zhu; Jung-Wei Fan; David M Baorto; Chunhua Weng; James J Cimino
Journal:  J Biomed Inform       Date:  2009-03-12       Impact factor: 6.317

7.  Identifying mismatches in alignments of large anatomical ontologies.

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Journal:  AMIA Annu Symp Proc       Date:  2007-10-11

8.  An analysis of multi-type relational interactions in FMA using graph motifs with disjointness constraints.

Authors:  Guo-Qiang Zhang; Lingyun Luo; Chime Ogbuji; Cliff Joslyn; Jose Mejino; Satya S Sahoo
Journal:  AMIA Annu Symp Proc       Date:  2012-11-03

9.  Analyzing polysemous concepts from a clinical perspective: application to auditing concept categorization in the UMLS.

Authors:  Fleur Mougin; Olivier Bodenreider; Anita Burgun
Journal:  J Biomed Inform       Date:  2009-03-18       Impact factor: 6.317

10.  Dissecting the Ambiguity of FMA Concept Names Using Taxonomy and Partonomy Structural Information.

Authors:  Lingyun Luo; Rong Xu; Guo-Qiang Zhang
Journal:  AMIA Jt Summits Transl Sci Proc       Date:  2013-03-18
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  7 in total

1.  COHeRE: Cross-Ontology Hierarchical Relation Examination for Ontology Quality Assurance.

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Journal:  AMIA Annu Symp Proc       Date:  2015-11-05

2.  Biological Model Development as an Opportunity to Provide Content Auditing for the Foundational Model of Anatomy Ontology.

Authors:  Lucy L Wang; Eli Grunblatt; Hyunggu Jung; Ira J Kalet; Mark E Whipple
Journal:  AMIA Annu Symp Proc       Date:  2015-11-05

Review 3.  Assessing the practice of biomedical ontology evaluation: Gaps and opportunities.

Authors:  Muhammad Amith; Zhe He; Jiang Bian; Juan Antonio Lossio-Ventura; Cui Tao
Journal:  J Biomed Inform       Date:  2018-02-17       Impact factor: 6.317

4.  MaPLE: A MapReduce Pipeline for Lattice-based Evaluation and Its Application to SNOMED CT.

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Journal:  Proc IEEE Int Conf Big Data       Date:  2014-10

5.  Using logical constraints to validate statistical information about disease outbreaks in collaborative knowledge graphs: the case of COVID-19 epidemiology in Wikidata.

Authors:  Houcemeddine Turki; Dariusz Jemielniak; Mohamed A Hadj Taieb; Jose E Labra Gayo; Mohamed Ben Aouicha; Mus'ab Banat; Thomas Shafee; Eric Prud'hommeaux; Tiago Lubiana; Diptanshu Das; Daniel Mietchen
Journal:  PeerJ Comput Sci       Date:  2022-09-29

6.  NEO: Systematic Non-Lattice Embedding of Ontologies for Comparing the Subsumption Relationship in SNOMED CT and in FMA Using MapReduce.

Authors:  Wei Zhu; Guo-Qiang Zhang; Shiqiang Tao; Mengmeng Sun; Licong Cui
Journal:  AMIA Jt Summits Transl Sci Proc       Date:  2015-03-25

7.  Automatic Structuring of Ontology Terms Based on Lexical Granularity and Machine Learning: Algorithm Development and Validation.

Authors:  Lingyun Luo; Jingtao Feng; Huijun Yu; Jiaolong Wang
Journal:  JMIR Med Inform       Date:  2020-11-25
  7 in total

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