Literature DB >> 23556560

Breakup of finite thickness viscous shell microbubbles by ultrasound: a simplified zero-thickness shell model.

Chao-Tsung Hsiao1, Georges L Chahine.   

Abstract

A simplified three-dimensional (3-D) zero-thickness shell model was developed to recover the non-spherical response of thick-shelled encapsulated microbubbles subjected to ultrasound excitation. The model was validated by comparison with previously developed models and was then used to study the mechanism of bubble break-up during non-spherical deformations resulting from the presence of a nearby rigid boundary. The effects of the shell thickness and the bubble standoff distance from the solid wall on the bubble break-up were studied parametrically for a fixed insonification frequency and amplitude. A diagram of bubble shapes versus the normalized shell thickness and wall standoff was derived, and the potential bubble shapes at break-up from reentrant jets were categorized resulting in four distinct zones.

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Year:  2013        PMID: 23556560      PMCID: PMC4109778          DOI: 10.1121/1.4792492

Source DB:  PubMed          Journal:  J Acoust Soc Am        ISSN: 0001-4966            Impact factor:   1.840


  16 in total

1.  Gene transfection and drug delivery.

Authors:  M W Miller
Journal:  Ultrasound Med Biol       Date:  2000-05       Impact factor: 2.998

Review 2.  Therapeutic applications of microbubbles.

Authors:  Evan C Unger; Terry Onichi Matsunaga; Thomas McCreery; Patricia Schumann; Robert Sweitzer; Rachel Quigley
Journal:  Eur J Radiol       Date:  2002-05       Impact factor: 3.528

3.  Influence of injection site, microvascular pressure and ultrasound variables on microbubble-mediated delivery of microspheres to muscle.

Authors:  Ji Song; John C Chappell; Ming Qi; Eric J VanGieson; Sanjiv Kaul; Richard J Price
Journal:  J Am Coll Cardiol       Date:  2002-02-20       Impact factor: 24.094

4.  Stability analysis of ultrasound thick-shell contrast agents.

Authors:  Xiaozhen Lu; Georges L Chahine; Chao-Tsung Hsiao
Journal:  J Acoust Soc Am       Date:  2012-01       Impact factor: 1.840

5.  Characterization of ultrasound contrast microbubbles using in vitro experiments and viscous and viscoelastic interface models for encapsulation.

Authors:  Kausik Sarkar; William T Shi; Dhiman Chatterjee; Flemming Forsberg
Journal:  J Acoust Soc Am       Date:  2005-07       Impact factor: 1.840

Review 6.  Ultrasound microbubble contrast agents: fundamentals and application to gene and drug delivery.

Authors:  Katherine Ferrara; Rachel Pollard; Mark Borden
Journal:  Annu Rev Biomed Eng       Date:  2007       Impact factor: 9.590

Review 7.  Ultrasonic gene and drug delivery to the cardiovascular system.

Authors:  Christian R Mayer; Raffi Bekeredjian
Journal:  Adv Drug Deliv Rev       Date:  2008-04-03       Impact factor: 15.470

8.  Evaluation of gas-filled microparticles and sonoporation as gene delivery system: feasibility study in rodent tumor models.

Authors:  Peter Hauff; Stefanie Seemann; Regina Reszka; Marcus Schultze-Mosgau; Michael Reinhardt; Tivadar Buzasi; Thomas Plath; Stefan Rosewicz; Michael Schirner
Journal:  Radiology       Date:  2005-08       Impact factor: 11.105

9.  Efficient gene delivery to pancreatic islets with ultrasonic microbubble destruction technology.

Authors:  Shuyuan Chen; Jia-huan Ding; Raffi Bekeredjian; Bing-zhi Yang; Ralph V Shohet; Stephen A Johnston; Hans E Hohmeier; Christopher B Newgard; Paul A Grayburn
Journal:  Proc Natl Acad Sci U S A       Date:  2006-05-18       Impact factor: 11.205

10.  Three-dimensional modeling of the dynamics of therapeutic ultrasound contrast agents.

Authors:  Chao-Tsung Hsiao; Xiaozhen Lu; Georges Chahine
Journal:  Ultrasound Med Biol       Date:  2010-10-15       Impact factor: 2.998

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  3 in total

Review 1.  Cell mechanics in biomedical cavitation.

Authors:  Qianxi Wang; Kawa Manmi; Kuo-Kang Liu
Journal:  Interface Focus       Date:  2015-10-06       Impact factor: 3.906

2.  High-speed video microscopy and numerical modeling of bubble dynamics near a surface of urinary stone.

Authors:  Yuri A Pishchalnikov; William M Behnke-Parks; Kevin Schmidmayer; Kazuki Maeda; Tim Colonius; Thomas W Kenny; Daniel J Laser
Journal:  J Acoust Soc Am       Date:  2019-07       Impact factor: 1.840

3.  Contrast agent shell properties effects on heat deposition in bubble enhanced high intensity focused ultrasound.

Authors:  Aswin Gnanaskandan; Chao-Tsung Hsiao; Georges Chahine
Journal:  J Acoust Soc Am       Date:  2021-01       Impact factor: 1.840

  3 in total

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